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Inhibition of melanogenesis by sodium 2-mercaptoethanesulfonate

Kim JH, Oh CT, Kwon TR, Kim JH, Bak DH, Kim H, Park WS, Kim BJ

Sodium 2-mercaptoethanesulfonate (mesna) is a protective agent that is widely used in medicine because of its antioxidant effects. Recently, reactive oxygen species (ROS) were shown to increase pigmentation. Thus, ROS...
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Antioxidant, Anti-Melanogenic and Anti-Wrinkle Effects of Phellinus vaninii

Im KH, Baek SA, Choi J, Lee TS

In this study, the antioxidant, anti-xanthine oxidase, anti-melanogenic and anti-wrinkle effects of methanol (ME) and hot water (HE) extracts from the fruiting bodies of Phellinus vaninii were investigated. The 1,1-diphenyl-2-picryl-hydrazyl...
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Anti-melanogenesis and Anti-inflammatory Effects of Cinnamomi Cortex Extract In Vitro

Park JH, Park SJ, Park KY, Kim BJ

  • KMID: 2465952
  • Korean J Dermatol.
  • 2019 Sep;57(8):448-456.
BACKGROUND: Many researchers have sought to identify safe, natural herbal extracts that exert an anti-melanogenesis effect. Cinnamomi cortex has been widely used as a herbal medicine in Asia and Europe. OBJECTIVE:...
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Anti-melanogenic effects of Hordeum vulgare L. barely sprout extract in murine B16F10 melanoma cells

Choi JH, Jung JG, Kim JE, Bang MA

PURPOSE: Barely sprout is a well-known oriental herbal medicine with a wide range of health benefits. Recent studies have provided scientific evidence of its therapeutic effects with expanded application. This...
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Primary Malignant Melanoma of the Breast: A Report of Two Cases

Koh J, Lee J, Jung SY, Kang HS, Yun T, Kwon Y

Primary malignant melanoma of the breast (PMMB) is a rare tumor with only a few case reports available in the literature. We report two cases of PMMB, one derived from...
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Anti-Melanogenic Effect from Submerged Mycelial Cultures of Ganoderma weberianum

Lai YJ, Hsu KD, Huang TJ, Hsieh CW, Chan YH, Cheng KC

Compounds from Lingzhi has been demonstrated the ability for inhibiting tyrosinase (a key enzyme in melanogenesis) activity. In this study, we investigated the anti-melanogenic activity from the submerged mycelial culture...
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A Case of Segmental Vitiligo Occurring Where Herpes Zoster Occurred Previously as an Isotopic Response

Kim JY, Lee YH, Lim JY, Choi JY, Min JH, Choi YJ, Nam JH, Kim WS, Lee GY

  • KMID: 2436995
  • Korean J Dermatol.
  • 2018 Nov;56(9):543-547.
Wolf's isotopic response is defined as the occurrence of a new skin disorder at the site of another unrelated skin disease that has already healed. In most cases of isotopic...
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Effective Treatment for Post-inflammatory Hyperpigmentation Caused by Cosmetic Procedures

Lim Y, Lee JH

  • KMID: 2436736
  • Korean J Dermatol.
  • 2018 Jul;56(6):363-367.
BACKGROUND: Postinflammatory hyperpigmentation (PIH) is one of the most common adverse effects associated with dermatologic procedures, especially those for cosmetic purposes. Low fluence Q-Switched Nd:YAG laser (LFQS) has been widely...
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Progressive Cribriform and Zosteriform Hyperpigmentation: A Case Series and Review of the Literature

Lee SK, Suh JH, Kim MS, Lee UH

  • KMID: 2436708
  • Korean J Dermatol.
  • 2018 Jun;56(5):338-342.
Progressive cribriform and zosteriform hyperpigmentation (PCZH) is a distinctive pigmentary disorder observed along the lines of Blaschko. Clinically, the lesions appear as uniformly tan, cribriform macular hyperpigmentation with a zosteriform...
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Deeper Wrinkle Formation and Less Melanin Production in Aged Korean Women with B Blood Type

Oh JH, Oh IG, Park CH, Shin MK, Lee SR, Lee DH, Choi M, Jin SP, Yoon HS, Cho S, Chung JH

No abstract available.
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The effects of green tea (Camellia sinensis) flower extracton melanin synthesis in B16-F10 melanoma cells

Dissanayake CY, Moon HH, Yang KM, Lee Y, Han CH

The present study observed the effects of a green tea (Camellia sinensis) flower extract (GTFE) on melanin synthesis in B16-F10 melanoma cells. GTFE exhibited antioxidant activity on 2,2-diphenyl-1-picrylhydrazyl and inhibited...
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Designing Tyrosinase siRNAs by Multiple Prediction Algorithms and Evaluation of Their Anti-Melanogenic Effects

Kwon OS, Kwon SJ, Kim JS, Lee G, Maeng HJ, Lee J, Hwang GS, Cha HJ, Chun KH

Melanin is a pigment produced from tyrosine in melanocytes. Although melanin has a protective role against UVB radiation-induced damage, it is also associated with the development of melanoma and darker...
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Artemisia capillaris Thunb. inhibits melanin synthesis activity via ERK-dependent MITF pathway in B16/F10 melanoma cells

Saba E, Oh MJ, Lee YY, Kwak D, Kim S, Rhee MH

Genus Artemisia occurs as a hardy plant and has a wide range of culinary and medicinal features. In this study, we aimed to describe the melanin inhibitory activity of one...
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Clinicopathological Analysis of Pigmented Contact Dermatitis Caused by Henna Dyeing

Jeon HW, Lee JB, Lee SC, Won YH, Yun SJ

  • KMID: 2436663
  • Korean J Dermatol.
  • 2018 Mar;56(3):161-166.
BACKGROUND: Henna is a natural dye derived from the leaves of the tree Lawsonia inermis known for its very low allergic properties. Recently, however, cases of pigmented contact dermatitis after...
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Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway

Ko GA, Shrestha S, Kim Cho S

BACKGROUND/OBJECTIVES: Sageretia thea is traditionally used as a medicinal herb to treat various diseases, including skin disorders, in China and Korea. This study evaluated the inhibitory effect of Sageretia thea...
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Ethyl linoleate inhibits α-MSH-induced melanogenesis through Akt/GSK3β/β-catenin signal pathway

Ko GA, Kim Cho S

Ethyl linoleate is an unsaturated fatty acid used in many cosmetics for its various attributes, such as antibacterial and anti-inflammatory properties and clinically proven to be an effective anti-acne agent....
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A Case of Punctate Leukoderma after 1,064 nm Q-Switched Nd:YAG Laser

Kwon O, Choi Y, Chung H, Park J

Punctate leukoderma is characterized of the destruction of melanocytes after chemical of physical damage. In addition, the term is broadly used to describe hypopigmented lesions induced in vitiligo patients after...
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Permanent Makeup Removal from Murine Skin Using 1,064-nm Q-switched Nd:YAG Laser and 694-nm Q-switched Ruby Laser: Comparing the Degree of Removal Following Irradiation at Different Time Points after Application

Jung GH, Kim HJ, Kim JE, Lee JS, Park YL, Whang KU, Lee SY

  • KMID: 2401252
  • Korean J Dermatol.
  • 2017 Dec;55(10):657-663.
BACKGROUND: Q-switched lasers have made it possible to remove tattoos without leaving unsightly scars. OBJECTIVE: Tobdetermine the optimal time for permanent makeup removal using Q-switched Nd:YAG and ruby lasers, we compared...
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Hyperpigmentation of the hard palate mucosa in a patient with chronic myeloid leukaemia taking imatinib

Bombeccari GP, Garagiola , Pallotti F, Rossi M, Porrini M, Giannì AB, Spadari F

BACKGROUND: Imatinib mesylate is an inhibitor of the tyrosine kinase Bcr–Abl and a first-line treatment for Philadelphia chromosome-positive chronic myeloid leukaemia (CML). Dermatological side effects include superficial oedema, pustular eruption,...
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Treatment of Melasma and Post-Inflammatory Hyperpigmentation by a Picosecond 755-nm Alexandrite Laser in Asian Patients

Lee YJ, Shin HJ, Noh TK, Choi KH, Chang SE

The picosecond lasers have shown to effectively treat tattoo pigments that are intractable to previous multiple Q-switched (QS) laser treatments. Therefore we hypothesized that a picosecond laser would show better...
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