- Epigenetic Regulation of Filaggrin Gene Expression in Human Epidermal Keratinocytes
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Lee J, Jang A, Seo SJ, Myung SC
- KMID: 2471338
- Ann Dermatol.
- 2020 Apr;32(2):122-129.
- doi: 10.5021/ad.2020.32.2.122
BACKGROUND: Loss-of-function mutations in the filaggrin gene (FLG), which encodes an epidermal protein crucial for the formation of a functional skin barrier, have been identified as a major predisposing factor... -
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- Exploratory Study of Epidermis, Basement Membrane Zone, Upper Dermis Alterations and Wnt Pathway Activation in Melasma Compared to Adjacent and Retroauricular Skin
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Espósito , Brianezi G, de Souza N, Miot LD, Miot HA
- KMID: 2471335
- Ann Dermatol.
- 2020 Apr;32(2):101-108.
- doi: 10.5021/ad.2020.32.2.101
BACKGROUND: Melasma is a chronic acquired focal hypermelanosis which pathogenesis has not been fully elucidated. Classical pathophysiologic studies have analysed the affected and perilesional areas, but little is known about... -
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- Eccrine Syringofibroadenoma Associated with Bowen's Disease: A Case Report and Review of the Literature
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Lee JS, Park H, Yoon HS, Cho S
- KMID: 2467202
- Ann Dermatol.
- 2020 Feb;32(1):57-63.
- doi: 10.5021/ad.2020.32.1.57
Eccrine syringofibroadenoma (ESFA) is a rare, benign adnexal neoplasm which usually manifests as a solitary nodule on the extremities of elderly patients. Few case reports have described an association between... -
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- Nailbed malignant melanoma in three dogs
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- KMID: 2470122
- Korean J Vet Res.
- 2019 Dec;59(4):219-222.
- doi: 10.14405/kjvr.2019.59.4.219
Three 8-12-year-old male cocker spaniels presented with an appendicular mass accompanied by pain, inflammation, lameness, and loss of nail in the digits of the forelimb or hindlimb. A histological examination... -
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- Particulate Matter-Induced Aryl Hydrocarbon Receptor Regulates Autophagy in Keratinocytes
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Jang HS, Lee JE, Myung CH, Park JI, Jo CS, Hwang JS
- KMID: 2462884
- Biomol Ther.
- 2019 Nov;27(6):570-576.
- doi: 10.4062/biomolther.2019.025
Particulate matter (PM), which refers to the mixture of particles present in the air, can have harmful effects. Damage to cells by PM, including disruption of organelles and proteins, can... -
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- Rab25 Deficiency Perturbs Epidermal Differentiation and Skin Barrier Function in Mice
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Jeong H, Lim KM, Goldenring JR, Nam KT
- KMID: 2462882
- Biomol Ther.
- 2019 Nov;27(6):553-561.
- doi: 10.4062/biomolther.2019.125
Rab25, a member of the Rab11 small GTPase family, is central to achieving cellular polarity in epithelial tissues. Rab25 is highly expressed in epithelial cells of various tissues including breast,... -
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- A Case of Immunoglobulin A Pemphigus: Intraepidermal Neutrophilic Dermatosis Type
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Heo JH, Yoon HS, Lee SH, Yeom SD, Kim L, Kim SC, Byun JW, Shin J, Choi GS
- KMID: 2465959
- Korean J Dermatol.
- 2019 Sep;57(8):492-495.
Immunoglobulin A (IgA) pemphigus is a rare variant of an autoimmune bullous disease with IgA antibodies. IgA pemphigus is divided into 2 major subtypes: the subcorneal pustular dermatosis (SPD) type... -
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- Enrichment of Short-Chain Ceramides and Free Fatty Acids in the Skin Epidermis, Liver, and Kidneys of db/db Mice, a Type 2 Diabetes Mellitus Model
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Kim M, Jeong H, Lee B, Cho Y, Yoon WK, Cho A, Kwon G, Nam KT, Ha H, Lim KM
- KMID: 2456220
- Biomol Ther.
- 2019 Sep;27(5):457-465.
- doi: 10.4062/biomolther.2018.214
Patients with diabetes mellitus (DM) often suffer from diverse skin disorders, which might be attributable to skin barrier dysfunction. To explore the role of lipid alterations in the epidermis in... -
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- Mammary Paget's Disease of the Nipple: Relatively Common but Still Unknown to Many
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Ooi PS, Draman N, Yusoff SS, Zain WZ, Ganasagaran D, Chua HH
- KMID: 2454765
- Korean J Fam Med.
- 2019 Jul;40(4):269-272.
- doi: 10.4082/kjfm.17.0143
Mammary Paget's disease is clinically defined as skin inflammation of the nipple area and is an adenocarcinoma of the epidermis of the nipple. The pathogenesis of mammary Paget's disease is... -
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- Acquired Reactive Perforating Collagenosis as a Preceding Manifestation of Hodgkin's Lymphoma
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Lee SY, Bang CH, Park YM, Lee JY, Lee JH
- KMID: 2454375
- Korean J Dermatol.
- 2019 Jul;57(6):332-334.
A 40-year-old man presented with pruritic, multiple, variable-sized, erythematous umbilicated papules on the trunk and both extremities for 4 months. He was diagnosed with Hodgkin's lymphoma (stage IIA) after histopathologic... -
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- Adiponectin Attenuates the Inflammation in Atopic Dermatitis-Like Reconstructed Human Epidermis
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Seo HS, Seong KH, Kim CD, Seo SJ, Park BC, Kim MH, Hong SP
- KMID: 2439064
- Ann Dermatol.
- 2019 Apr;31(2):186-195.
- doi: 10.5021/ad.2019.31.2.186
BACKGROUND: Atopic dermatitis (AD) is a chronic disorder, with a vicious cycle of repetitive inflammation and deterioration of the epidermal barrier function. Adiponectin, an adipokine, has anti-inflammatory effects on various... -
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- Neuropeptides Profile and Increased Innervation in Becker's Nevus
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Kim JS, Park MJ, Kang HY, Hong SP, Park BC, Kim MH
- KMID: 2439061
- Ann Dermatol.
- 2019 Apr;31(2):154-163.
- doi: 10.5021/ad.2019.31.2.154
BACKGROUND: Melanocytes are derived from neural crest, and various pigmentary disorders may accompany abnormalities in nerve system or develop following dermatome, suggesting that melanocyte and pigmentation may be closely related... -
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- Mannosylerythritol lipids ameliorate ultraviolet A-induced aquaporin-3 downregulation by suppressing c-Jun N-terminal kinase phosphorylation in cultured human keratinocytes
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Bae IH, Lee SH, Oh S, Choi H, Marinho PA, Yoo JW, Ko JY, Lee ES, Lee TR, Lee CS, Kim DY
- KMID: 2438085
- Korean J Physiol Pharmacol.
- 2019 Mar;23(2):113-120.
- doi: 10.4196/kjpp.2019.23.2.113
Mannosylerythritol lipids (MELs) are glycolipids and have several pharmacological efficacies. MELs also show skin-moisturizing efficacy through a yet-unknown underlying mechanism. Aquaporin-3 (AQP3) is a membrane protein that contributes to the... -
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- Anti-tuberculosis Drugs-induced Anagen Effluvium with Generalized Drug Eruption
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Lim C, Park KD, Seo YJ, Lee J, Lee Y
- KMID: 2433638
- Korean J Dermatol.
- 2019 Jan;57(1):15-19.
Anagen effluvium is an abrupt loss of hair in its growing phase due to an event that impairs the mitotic or metabolic activity of the hair follicle. Anagen effluvium is... -
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- Reconstruction of cutaneous defects of the nasal tip and alar by two different methods
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Kim YH, Yoon HW, Chung S, Chung YK
- KMID: 2432588
- Arch Craniofac Surg.
- 2018 Dec;19(4):260-263.
- doi: 10.7181/acfs.2018.02271
BACKGROUND: The alar and nasal tip are important subunits of the nose. Determining the optimal procedure for reconstructing a cutaneous defect in a nasal subunit depends on several factors including... -
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- From Bench to Clinic: the Potential of Therapeutic Targeting of the IL-22 Signaling Pathway in Atopic Dermatitis
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Jin M, Yoon J
- KMID: 2429834
- Immune Netw.
- 2018 Dec;18(6):e42.
- doi: 10.4110/in.2018.18.e42
Atopic dermatitis (AD) is the most common pruritic inflammatory skin disease characterized by thickening of epidermis and dermis as well as by the infiltration of multiple pathogenic polarized T lymphocytes,... -
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- The Effects of the 3-OH Group of Kaempferol on Interfollicular Epidermal Stem Cell Fate
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Chae JB, Choi HR, Shin JW, Na JI, Huh CH, Park KC
- KMID: 2428925
- Ann Dermatol.
- 2018 Dec;30(6):694-700.
- doi: 10.5021/ad.2018.30.6.694
BACKGROUND: Kaempferol (3,4′,5,7-tetrahydroxyflavone) is a flavonoid known to have a wide range of pharmacological activities. The 3-OH group in flavonoids has been reported to determine antioxidant activities. OBJECTIVE: We tested whether... -
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- Pathophysiology and new treatment of itch
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Jung MJ, Choi YW, Chung BY, Park CW, Kim HO
- KMID: 2426477
- J Korean Med Assoc.
- 2018 Nov;61(11):670-677.
- doi: 10.5124/jkma.2018.61.11.670
Many of the patients visit the doctors because of itching sensation. Itching is an unpleasant sensation. In the epidermal keratinocytes, various neurotransmitters and receptors are related itching. The itch signal... -
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- Medical adhesive related skin injury after dental surgery
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Kim TH, Lee JS, Ahn JH, Kim CH, Yoon JU, Kim EJ
- KMID: 2424372
- J Dent Anesth Pain Med.
- 2018 Oct;18(5):305-308.
- doi: 10.17245/jdapm.2018.18.5.305
An 87-year-old woman was referred for the extraction of residual teeth and removal of tori prior to prosthetic treatment. After surgery under general anesthesia, the surgical tape was removed to... -
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- Clinical and Histopathologic Study of Confluent and Reticulated Papillomatosis by Anatomic Site and Age
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Cho YM, Jung KE, Koo DW, Lee JS
- KMID: 2419744
- Ann Dermatol.
- 2018 Oct;30(5):550-555.
- doi: 10.5021/ad.2018.30.5.550
BACKGROUND: Confluent and reticulated papillomatosis (CRP) is an uncommon dermatosis characterized by hyperpigmented scaly macules or papillomatous papules coalescing into confluent patches or plaques centrally with a reticular pattern peripherally.... -
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