Korean J Spine.  2016 Sep;13(3):129-133. 10.14245/kjs.2016.13.3.129.

The Use of Gentamicin-Impregnated Collagen Sponge for Reducing Surgical Site Infection after Spine Surgery

Affiliations
  • 1Department of Neurosurgery, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea. sehoonkim.ns@gmail.com

Abstract


OBJECTIVE
Surgical site infection (SSI) is the one of the most frequent complications in hospitalized patients, and it extends hospital stays and causes extra morbidities. To reduce SSI after spine surgery, we applied the gentamicin-impregnated collagen sponge (Collatamp G) during the operation and analyzed the results retrospectively.
METHODS
Between October 2012 and December 2015, we collected data who applied the Collatamp G in spine surgery at a single institution. Demographic data of patients and another possible risk factors of SSI were also included, and we assessed the correlation between the risk factors and the developing of SSI by reviewing electronic medical records retrospectively.
RESULTS
Three percent of all patients (10 of 280) developed the SSI and only 0.8% of patients who applied Collatamp G developed SSI (1 of 119). Otherwise, 5% of patients who did not apply Collatamp G developed SSI (9 of 161) (p=0.034). We also analyzed the correlation between SSI and other potential risk factors but nothings showed statistical correlation with SSI.
CONCLUSION
In this study, there were statistically significant results that SSI rate was decreased in the group of patients using Collatamp G in spine surgery generally. However, further studies are required to resolve some limitations in the future.

Keyword

Gentamicin; Collagen; Surgical wound infection

MeSH Terms

Collagen*
Electronic Health Records
Gentamicins
Humans
Length of Stay
Porifera*
Retrospective Studies
Risk Factors
Spine*
Surgical Wound Infection*
Collagen
Gentamicins
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