J Korean Ophthalmol Soc.  1988 Dec;29(6):1043-1048.

Bleomycin in a Collagen Sponge and Glaucoma Filtering Surgery

Affiliations
  • 1Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

A histologic study was performed if fibroblast proliferation could be inhibited in rab bits by deli very of bleomycin(1.35mg), an antineoplastic antibiotics, in a collagen sponge implant. Results showed that fibroblast proliferation was markedly inhibited and bleb longevity was prolonged when compared to controls. And inflammatory cell infiltration was noted around filtration wound.


MeSH Terms

Antibiotics, Antineoplastic
Bleomycin*
Blister
Collagen*
Fibroblasts
Filtering Surgery*
Filtration
Glaucoma*
Longevity
Porifera*
Wounds and Injuries
Antibiotics, Antineoplastic
Bleomycin
Collagen
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