J Korean Ophthalmol Soc.
1988 Dec;29(6):1043-1048.
Bleomycin in a Collagen Sponge and Glaucoma Filtering Surgery
- Affiliations
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- 1Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.
Abstract
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A histologic study was performed if fibroblast proliferation could be inhibited in rab bits by deli very of bleomycin(1.35mg), an antineoplastic antibiotics, in a collagen sponge implant. Results showed that fibroblast proliferation was markedly inhibited and bleb longevity was prolonged when compared to controls. And inflammatory cell infiltration was noted around filtration wound.