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Clinical Impact of Implantable Cardioverter-Defibrillator Therapy and Mortality Prediction Model for Effective Primary Prevention in Korean Patients

Bae MH, Cho Y, Hwang J, Park HS, Han S, Lee YS, Cho HJ, Jung BC, Lee CH, Hyun DW, Park JS, Ahn J, Kim KH, Shin DG

BACKGROUND: Studies on the efficacy of implantable cardioverter-defibrillator (ICD) therapy for primary prevention in Asian patients are relatively lacking compared to those for secondary prevention. Also, it is important to...
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Metformin Treatment for Patients with Diabetes and Chronic Kidney Disease: A Korean Diabetes Association and Korean Society of Nephrology Consensus Statement

Hur KY, Kim MK, Ko SH, Han M, Lee DW, Kwon HS, Committee of Clinical Practice Guidelines, Korean Diabetes Association, Committee of the Cooperative Studies, Korean Society of Nephrology

The safety of metformin use for patients with type 2 diabetes mellitus (T2DM) and advanced kidney disease is controversial, and more recent guidelines have suggested that metformin be used cautiously...
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Factors Affecting Vascular Clogging, Wound Status and Bacterial Culture in Diabetic Foot Ulcers

Kim JL, Shin JY, Roh SG, Chang SC, Lee NH

BACKGROUND: We assumed that vascular clogging, wound status, and bacterial culture tests are significant characteristics in developing a treatment plan for diabetic patients with foot ulcers. The goal of our...
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Increased Carotid Intima-Media Thickness (IMT) in Hyperuricemic Individuals May Be Explained by Hyperhomocysteinemia Associated with Renal Dysfunction: a Cross-Sectional Study

Park JH, Song JS, Choi ST

BACKGROUND: Both hyperuricemia and hyperhomocysteinemia are known as main risk factors of cardiovascular diseases. There has been, however, no report on the relationship between carotid intima-media thickness (IMT) and homocysteine...
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Perirenal fat thickness is associated with metabolic risk factors in patients with chronic kidney disease

D'Marco L, Salazar J, Cortez M, Salazar M, Wettel M, Lima-Martínez M, Rojas E, Roque W, Bermúdez

BACKGROUND: Adipose tissue accumulation in specific body compartments has been associated with diabetes, hypertension and dyslipidemia. Perirenal fat (PRF) may lead to have direct lipotoxic effects on renal function and...
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Effects of percutaneous angioplasty on kidney function and blood pressure in patients with atherosclerotic renal artery stenosis

Kim S, Kim MJ, Jeon J, Jang HR, Park KB, Huh W, Do YS, Kim YG, Kim DJ, Oh HY, Lee JE

BACKGROUND: Previous randomized controlled trials of revascularization for atherosclerotic renal artery stenosis (ARAS) were not successful. We investigated the effects of percutaneous transluminal angioplasty with stent insertion (PTA/S) on kidney...
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Approximation of bicarbonate concentration using serum total carbon dioxide concentration in patients with non-dialysis chronic kidney disease

Hirai K, Minato S, Kaneko S, Yanai K, Ishii H, Kitano T, Shindo M, Miyazawa H, Ito K, Ueda Y, Kaku Y, Hoshino T, Watano T, Fujino S, Ookawara S, Omoto K, Morishita

BACKGROUND: We investigated the relationship between serum total carbon dioxide (CO₂) and bicarbonate ion (HCO₃⁻) concentrations in pre-dialysis chronic kidney disease (CKD) patients and devised a formula for predicting low...
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The Protective Effects of Increasing Serum Uric Acid Level on Development of Metabolic Syndrome

Yu TY, Jin SM, Jee JH, Bae JC, Lee MK, Kim JH

BACKGROUND: It has not been determined whether changes in serum uric acid (SUA) level are associated with incident metabolic syndrome (MetS). The aim of the current study was to investigate...
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Factors Related to Blood Intact Incretin Levels in Patients with Type 2 Diabetes Mellitus

Yoo S, Yang EJ, Koh G

BACKGROUND: We performed this study to identify factors related to intact incretin levels in patients with type 2 diabetes mellitus (T2DM). METHODS: We cross-sectionally analyzed 336 patients with T2DM. Intact glucagon-like...
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Value of the Filtration Fraction Assessed by Dynamic ⁹⁹mTc-Diethylenetriaminepentaacetic Acid Renal Scintigraphy After Angiotensin-Converting Enzyme Inhibition for the Diagnosis of Renovascular Hypertension

Shin E, Sung C, Son HJ, Lee DY, Chae SY, Moon DH

PURPOSE: This study aimed to determine the diagnostic value of the relative filtration fraction (RFF) assessed by dynamic ⁹⁹mTc-diethylenetriaminepentaacetic acid (⁹⁹mTc-DTPA) renal scintigraphy after angiotensin-converting enzyme (ACE) inhibition for renovascular...
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The Colonoscopic Characteristics and Clinical Manifestations Associated with Lower Gastrointestinal Tract Bleeding in Patients with Chronic Kidney Disease

Lee KJ, Koo HS, Kim YS, Min JH, Jo SY, Yoon WE, Lee DH, Kim JY, Moon JS, Koh HI

BACKGROUND/AIMS: Patients with chronic kidney disease (CKD) have a high risk of gastrointestinal tract bleeding because of platelet dysfunction attributable to uremia, a poor blood supply, and frequent use of...
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Effects of Prenatal Growth Status on Subsequent Childhood Renal Function Related to High Blood Pressure

Park B, Lee JW, Kim HS, Park EA, Cho SJ, Park H

BACKGROUND: Hypertension is one of the major causes of chronic diseases. The effect on high blood pressure (BP) with fetal growth restriction is now well-established. Recent studies suggest that a...
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Response: Predictors of the Therapeutic Efficacy and Consideration of the Best Combination Therapy of Sodium-Glucose Co-transporter 2 Inhibitors (Diabetes Metab J 2019;43:158–73)

Lee JY, Kang ES

No abstract available.
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Letter: Predictors of the Therapeutic Efficacy and Consideration of the Best Combination Therapy of Sodium-Glucose Co-transporter 2 Inhibitors (Diabetes Metab J 2019;43:158–73)

Kim KS

No abstract available.
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In-line Filtration in Parenteral Nutrition

Kim E, Seol EM

Metabolic abnormalities and catheter-related infections are common complications of parenteral nutrition (PN). Particulate contamination is a catheter-related complication can occur when administering PN: mixing the electrolytes, trace elements, vitamins into...
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The Effect of Theophylline on Improvement of Renal Function in Asphyxiated Neonates: A Systematic Review and Meta-analysis

Lee JW, Lee SY, An SH

The purpose of this systematic review and meta-analysis was to assess the preventive effect of theophylline on acute kidney injury and the ameliorative effect of theophylline on renal function in...
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Sub-morbid dehydration-associated glomerular hyperfiltration: An emerging reality?

Min HK, Sung SA, Lee SY, Lee SW

BACKGROUND: Severe dehydration decreases renal perfusion. However, it is unclear whether sub-morbid dehydration affects kidney function similarly. Although there have been numerous animal and human studies that have suggested mild...
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Adipose tissue-derived mesenchymal stromal cells for treating chronic kidney disease: A pilot study assessing safety and clinical feasibility

Villanueva S, González , Lorca E, Tapia A, Valentina López G, Strodthoff R, Fajre F, Carreño J, Valjalo R, Vergara C, Lecanda M, Bartolucci J, Figueroa F, Khoury M

BACKGROUND: Chronic kidney disease (CKD) is a growing public health concern, and available treatments are insufficient in limiting disease progression. New strategies, including regenerative cell-based therapies, have emerged as therapeutic...
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Prevention of Major Adverse Cardiovascular and Renal Outcomes with Sodium-Glucose Cotransporter 2 Inhibitors

Hong JH

Management of hyperglycemia limits progression of microvascular complications in type 2 diabetes mellitus (T2DM). According to large-scale randomized control studies to demonstrate the cardiovascular safety of sodium-glucose cotransporter 2 (SGLT2)...
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Sodium-Glucose Cotransporter 2 Inhibitors: Mechanisms of Action and Various Effects

Kim KS

The basic action mechanism of sodium-glucose cotransporter 2 (SGLT2) inhibitor is to lower the glucose burden by excreting the glucose filtered by the kidney into the urine. Although SGLT2 inhibitors...
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