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Topographic and Histologic Analysis of the Collateral Ligament Complex around the Elbow

Kim JP, Park JK, Yoo JY, Shin WJ, Kim JS, Kim YI

Purpose: The purpose of this study was to evaluate topographic anatomy of the footprints of key ligaments of the elbow and assess their relationships with bony parameters using micro-computed tomography...
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Specific Bioactive Collagen Peptides in Osteopenia and Osteoporosis: Long-Term Observation in Postmenopausal Women

Zdzieblik D, Oesser S, König D

Background: The effects of specific collagen peptides on bone mineral density (BMD) in subjects with osteoporosis or osteopenia have already been investigated in 131 postmenopausal women in a randomized controlled...
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Sclerotic Fibroma Presenting as an Axillary Mass: A Case Report with Imaging Features

Kim TE, Lee JY

Sclerotic fibroma or storiform collagenoma is a rare benign neoplasm that predominantly affects the skin layer of the head, neck, or limbs. Less frequently, it occurs in non-dermal spaces such...
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Irreversible Bladder Remodeling Induced by Fibrosis

Kim SJ, Kim J, Na YG, Kim KH

Underactive bladder and impaired bladder compliance are irreversible problems associated with bladder fibrosis. Remodeling of the extracellular matrix is regarded as an important mechanism associated with bladder fibrosis. However, various...
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Change of Extracellular Matrix of Human Vocal Fold Fibroblasts by Vibratory Stimulation

Kim JM, Shin SC, Kwon HK, Cheon YI, Ro JH, Lee BJ

Background and Objectives During speech, the vocal folds oscillate at frequencies ranging from 100–200 Hz with amplitudes of a few millimeters. Mechanical stimulation is an essential factor which affects metabolism...
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Long-term Outcome of Combined Laser-assisted Subepithelial Keratomileusis and Accelerated Corneal Crosslinking for Myopia

Yoon YS, Kim KY

Purpose: We compared clinical outcomes between combined laser-assisted subepithelial keratomileusis and accelerated collagen cross-linking (Avedro-LASEK), and LASEK alone. Methods: This retrospective study analyzed 38 eyes of 19 patients who had undergone...
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Characterization of the Onychomatricodermis Containing Onychofibroblasts of the Nail Unit : Histology, Immunohistochemistry, and Electron Microscopic Study

Lee D, Abudureyimu G, Park JH, Jang KT, Kwon GY, Shim JS

Background: We recently discovered the presence of specialized nail mesenchyme below the nail matrix and designated it as onychomatricodermis. Objective: We did further research to characterize the histologic, histochemical, immunohistochemical...
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Investigation of the Clinical Potential of Polarization-Sensitive Optical Coherence Tomography in a Laryngeal Tumor Model

Xin Z, Kim SW, Oak C, Kwon DY, Choi JH, Ko TY, Kim JH, Tang S, Ahn YC

BACKGROUND: The vocal cord tissue consists of three anatomical layers from the surface to deep inside: the epithelium that contains almost no collagen, the lamina propria that is composed of...
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The proper concentrations of dextrose and lidocaine in regenerative injection therapy: in vitro study

Woo MS, Park J, Ok SH, Park M, Sohn JT, Cho MS, Shin IW, Kim YA

Background: Prolotherapy is a proliferation therapy as an alternative medicine. A combination of dextrose solution and lidocaine is usually used in prolotherapy. The concentrations of dextrose and lidocaine used in...
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Inhibition of matrix metalloproteinases: a troubleshooting for dentin adhesion

Moraes IQSd, Nascimento TGd, Silva ATd, Silva de Lira LMS, Parolia A, Moraes Porto ICCd

Matrix metalloproteinases (MMPs) are enzymes that can degrade collagen in hybrid layer and reduce the longevity of adhesive restorations. As scientific understanding of the MMPs has advanced, useful strategies focusing...
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Effects of soft tissue grafting prior to orthodontic treatment on preventing gingival recession in dogs

Song YW, Jung H, Han SY, Paeng KW, Kim MJ, Cha JK, Choi YJ, Jung UW

Purpose: This study was conducted to assess the efficacy of prophylactic gingival grafting in the mandibular anterior labial area for preventing orthodontically induced gingival recession. Methods: Eight mongrel dogs received gingival...
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Gingival and bone healing patterns with ridge preservation in beagle dogs

Piao XH, Park HS, Na ER, Kim YJ, Moon JW

The aim of this study was to evaluate the clinical and histologic findings of bone and gingival healing patterns with ridge preservation. The mandibular third premolars were extracted from beagle...
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Evaluation of Collagen Gel-Associated Human Nasal Septum- Derived Chondrocytes As a Clinically Applicable Injectable Therapeutic Agent for Cartilage Repair

Lim MH, Jeun JH, Kim DH, Park SH, Kim SJ, Lee WS, Hwang SH, Lim JY, Kim SW

BACKGROUND: Articular cartilage injury has a poor repair ability and limited regeneration capacity with therapy based on articular chondrocytes (ACs) implantation. Here, we validated the hypothesis that human nasal septum-derived...
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Associations of COL2A1 Gene Polymorphisms and Ankylosing Spondylitis in the Korean Population

Son ES, Um SH, Youn MY

With highly active antiretroviral therapy, human immunodeficiency virus (HIV) infection is considered to be a manageable chronic disease. The improved prognosis increases the desire of individuals with HIV to have...
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PBT-6, a Novel PI3KC2γ Inhibitor in Rheumatoid Arthritis

Kim J, Jung KH, Yoo J, Park JH, Yan HH, Fang Z, Lim JH, Kwon SR, Kim MK, Park HJ, Hong SS

Phosphoinositide 3-kinase (PI3K) is considered as a promising therapeutic target for rheumatoid arthritis (RA) because of its involvement in inflammatory processes. However, limited studies have reported the involvement of PI3KC2γ...
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Molecular epidemiology and characterization of Streptococcus mutans strains in Korea

Kim SY, Bae IK, Lee JH, Shin JH, Kim JB

OBJECTIVES: We investigated the characteristics of Streptococcus mutans in the national culture collection from Korea. Twenty-nine (dental plaque, n=27; endodontic infections, n=1; blood, n=1) isolates were included in this study. METHODS:...
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A Novel COL4A1 Mutation in a Neonate with Intrauterine Intraventricular Hemorrhage and Porencephaly

Noh J, Jung E, Jung AY, Lee BH, Lee BS, Kim EAR, Kim KS

Collagen type IV alpha 1 (COL4A1) plays an important role in construction of the basement membranes of all human tissues, especially vessels. Mutations in COL4A1 lead to various multisystemic...
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Distinctive bone regeneration of calvarial defects using biphasic calcium phosphate supplemented ultraviolet-crosslinked collagen membrane

Hong I, Khalid AW, Pae HC, Cha JK, Lee JS, Paik JW, Jung UW, Choi SH

PURPOSE: To overcome several drawbacks of chemically-crosslinked collagen membranes, modification processes such as ultraviolet (UV) crosslinking and the addition of biphasic calcium phosphate (BCP) to collagen membranes have been introduced....
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Corneal Collagen Cross-linking for Corneal Ulcer from Moraxella Group

Woo SE, Lee SH

PURPOSE: To report a case of corneal collagen cross-linking for corneal ulcer caused by the Moraxella group. CASE SUMMARY: A 77-year-old male had decreased visual acuity for several days in his...
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Multilayer Collagen Sheet Graft for Corneal Perforation with a Corneal Ulcer

Kim SJ, Yang SC, Jo YJ, Lee JS

Purpose: To report a rare case of corneal perforation treated with a multilayer collagen sheet graft transplantation after amniotic membrane graft failure to prevent corneal perforation in a fungal corneal...
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