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Atelocollagen Injections Improve Outcomes in the Nonsurgical Treatment of Grade III Medial Collateral Ligament Injuries

Jang YH, Kim DS

Background: The purpose of this study was to evaluate the clinical outcomes of atelocollagen injections in isolated grade III medial collateral ligament (MCL) injuries of the knee joint. Methods: A total...
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Enhancing generation efficiency of liver organoids in a collagen scaffold using human chemically derived hepatic progenitors

Kim M, Kim Y, Silva ESS, Adisasmita M, Kim KS, Jung YK, Lee KG, Shin JH, Choi D

Backgrounds/Aims: Liver organoids have emerged as a powerful tool for studying liver biology and disease and for developing new therapies and regenerative medicine approaches. For organoid culture, Matrigel, a type...
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The Effect of γ-Aminobutyric Acid Intake on UVB- Induced Skin Damage in Hairless Mice

Zhao H, Park B, Kim MJ, Hwang SH, Kim TJ, Kim SU, Kwon I, Hwang JS

The skin, the largest organ in the body, undergoes age-related changes influenced by both intrinsic and extrinsic factors. The primary external factor is photoaging which causes hyperpigmentation, uneven skin surface,...
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A rare histopathological variant of Schwannoma with rosette-like arrangements and epithelioid cells: a case report from a histopathologist’s perspective

Mehendiratta M, Sant VK, Lakhanpal M, Chauhan K

Schwannomas exhibit histopathological variation that leads to diagnostic dilemmas, although less frequent in the oral cavity. We describe a case with unique histopathology and no relevant clinical history that adds...
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Protective effects of red orange (Citrus sinensis [L.] Osbeck [Rutaceae]) extract against UVA-B radiation-induced photoaging in Skh:HR-2 mice

Kim YH, Lim CY, Jung JI, Kim TY, Kim EJ

BACKGROUND/OBJECTIVES: The skin is the outermost organ of the human body and plays a protective role against external environmental damages, such as sunlight and pollution, which affect anti-oxidant defenses and...
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Examination of the effect of xenogeneic mesenchymal stem cells and conditioned medium on cartilage graft viability: a rabbit model

Unlu A, Bulbul MV, Erkan BK, Ozdemir İ, Keskin I, Sutcu M

Background Since cartilage, unlike skin, does not contain vessels, it obtains nutrition by diffusion. This reduces graft viability, resulting in problems such as reductions in size, changes in shape, and...
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Anti-Fibrotic Effects of DL-Glyceraldehyde in Hepatic Stellate Cells via Activation of ERK-JNK-Caspase-3 Signaling Axis

Samsuzzaman M, Kim SY

During liver injury, hepatic stellate cells can differentiate into myofibroblast-like structures, which are more susceptible to proliferation, migration, and extracellular matrix generation, leading to liver fibrosis. Anaerobic glycolysis is associated...
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Breast Tissue Reconstruction Using Polycaprolactone Ball Scaffolds in a Partial Mastectomy Pig Model

Shim KS, Ryu DH, Jo HS, Kim KB, Kim DH, Park YK, Heo M, Cho HE, Yoon ES, Lee WJ, Roh TS, Song SY, Baek W

BACKGROUND: Breast cancer patients suffer from lowered quality of life (QoL) after surgery. Breast conservancy surgery (BCS) such as partial mastectomy is being practiced and studied as an alternative to...
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Newborn with Dominant Dystrophic Epidermolysis Bullosa That Manifested as Aplasia Cutis Congenita at Birth

Namgoong W, Bae SP, Lee SG, Lee SE, Hahn WH

Dystrophic epidermolysis bullosa caused by a mutation in the COL7A1 gene that encodes for type VII collagen is a rare inherited skin disorder characterized by mucocutaneous fragility, resulting in blisters...
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Effects of CTHRC1 on odontogenic differentiation and angiogenesis in human dental pulp stem cells

Kim Js, Lee BN, Chang HS, Hwang IN, Oh WM, Hwang YC

Objectives: This study aimed to determine whether collagen triple helix repeat containing-1 (CTHRC1), which is involved in vascular remodeling and bone formation, can stimulate odontogenic differentiation and angiogenesis when administered...
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Refractive Outcomes of Combined LASEK and Accelerated Corneal Crosslinking for Moderate Myopia

Cho SI, Moon JY, Choi JS, Kim EK, Pak KH, Chung SK

Purpose: We compared 1 year refractive outcomes between combined laser-assisted subepithelial keratomileusis (LASEK) and accelerated collagen cross linking (CXL LASEK), and LASEK alone. Methods: The study was conducted as a retrospective...
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Novel Biomarkers of Health and Degeneration in Human Intervertebral Discs: In-depth Proteomic Analysis of Collagen Framework of Fetal, Healthy, Scoliotic, Degenerate, and Herniated Discs

Rajasekaran S, Soundararajan DCR, Nayagam SM, Tangavel C, Raveendran M, K S SVA, Shetty AP, Kanna RM

Study Design: Profiling proteins expressed in the nucleus pulposus (NP) of intervertebral discs (IVDs) in five different biological states. Purpose: To evaluate the molecular complexity of the collagen (COL) framework and...
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Effects of PB203 on the skin photoaging of ultraviolet B (UVB)-irradiated hairless mice and human keratinocytes

Ho SH, Kim D, Shin Y, Lee JO, Kim YJ, Lee JM, Jang Y, Park SJ

Repetitive or excessive exposure to ultraviolet (UV) radiation causes oxidative stress-mediated skin photoaging through the overproduction of reactive oxygen species. Actinidia polygama is known as a medical plant used in...
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A study on coating of collagen-containing hydroxyapatite on titanium using electrochemical deposition method

Choi B, Park YJ, Song HJ

In this study, a biomimetic coating in which hydroxyapatite (HAp) and collagen (Col), the major components of bone, were coated together on titanium was performed using the ECD method. The...
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Current Opinion in Molecular Pathology of Ameloblastoma: A Literature Review

Lee D, Li S, Jung H

Ameloblastoma is the most representative epithelial odontogenic tumor in the craniofacial region. Through several studies on Ameloblastoma that have been conducted so far, we have been able to get closer...
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Collagenous Gastoduodenitis in the Form of a Gastric Ulcer

Choi IH, Cho YK, Park JY, Kang D, Park JM, Choi MG

Collagenous gastroduodenitis is a rare gastrointestinal disease diagnosed histologically by subepithelial collagen deposition in the lamina propria. Its clinical presentation is diverse. The authors encountered a 17-year-old female patient who...
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Transcriptomic Comparison Analysis between Ameloblastoma and AM-1 Cell Line

Li S, Lee DJ, Kim HY, Harada H, Jung YS, Jung HS

Cancer initiation and progression are profoundly along with the crosstalk between cancer cells and the surrounding stroma. Accumulating evidence has shown that the therapy targeting the extracellular matrix (ECM) would...
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Changes in the Serum Levels of Parathyroid Hormone and Bone Metabolites in Two Serial Samples with Different Vitamin D Status

Park PW, Park IK

Background: Vitamin D increases serum calcium levels by promoting calcium absorption in intestines. Vitamin D deficiency raises the serum levels of parathyroid hormone (PTH) and bone metabolites. Generally, vitamin D...
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Quantification and comparison of tenocyte distribution and collagen content in the commonly used autografts for anterior cruciate ligament reconstruction

Latiff S, Olateju OI

Anterior cruciate ligament is a commonly damaged ligament of the knee. Reconstruction of this ligament usually entails the use of graft harvested from the same subject (i.e., autografts). Several tendons,...
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Inhibitory Effect of Mitoxantrone on Collagen Synthesis in Dermal Fibroblasts

Kim KI, Kwon CI, Lee JH, Kim CD, Yoon TJ

Background: Fibroblasts produce collagen molecules that support the structure of the skin. The decrease and hypersynthesis of collagen causes skin problems such as skin atrophy, wrinkles and scars. Objective: The purpose of...
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