Korean J Biol Psychiatry.
2016 Aug;23(3):108-115. 10.0000/kjbp.2016.23.3.108.
Aggression and Neurotransmitters
- Affiliations
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- 1Department of Brain and Cognitive Sciences, Scranton College, Ewha Womans University, Seoul, Korea. kjieun@ewha.ac.kr
- 2Ewha Brain Institute, Ewha Womans University, Seoul, Korea.
- 3Kim Sangjoon Law Firm, Seoul, Korea.
- 4Department of Radiology, Incheon St. Mary's Hospital, The Catholic University of Korea, Incheon, Korea.
- 5Interdisciplinary Program in Neuroscience, College of Natural Sciences, Seoul National University, Seoul, Korea.
- 6Department of Bio and Brain Engineering, KAIST, Daejeon, Korea.
- 7Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, Korea.
- 8Department of Psychology, College of Social Sciences, Seoul National University, Seoul, Korea.
- 9School of Business, Ewha Womans University, Seoul, Korea. ksshin@ewha.ac.kr
- KMID: 2351426
- DOI: http://doi.org/10.0000/kjbp.2016.23.3.108
Abstract
- Aggression and aggressive behaviors, often explained as harmful social interaction with the intention of hurting or inflicting damage upon another, have been considered as an adaptive mechanism from the evolutionary psychological point of view. However, various studies on aggression and aggressive behaviors have been done with psychopathological approach as the extreme aggressive behaviors may harm themselves and others at the same time. Recently, researchers have attempted to explain aggression in terms of neurobiological substrates rather than based on traditional psychopathological and/or behavioral concept. In this regard, there have been findings of differences in neurotransmitters and their receptors, and genetic polymorphisms. In this review article, we provide a brief overview of the literature about seven most frequently reported neurotransmitters including neurohormones (serotonin, norepinephrine, dopamine, gamma-aminobutyric acid, nitric oxide, oxytocin and vasopressin) and an associated enzyme (monoamine oxidase A), which are known to be related with aggression and aggressive behaviors.
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