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Inhibition of DNMT3B and PI3K/AKT/mTOR and ERK Pathways as a Novel Mechanism of Volasertib on Hypomethylating Agent-Resistant Cells

Choi EJ, Koo BK, Hur EH, Moon JH, Kim JY, Park HS, Choi Y, Lee KH, Lee JH, Choi EK, Lee JH

Resistance to hypomethylating agents (HMAs) in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) is a concerning problem. Polo-like kinase 1 (PLK1) is a key cell cycle modulator and is...
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Association between seafood intake and frailty according to gender in Korean elderly: data procured from the Seventh (2016–2018) Korea National Health and Nutrition Examination Survey

Jang W, Choi Y, Cho JH, Lee D, Kim Y

Purpose: This study investigates the association between seafood consumption and frailty according to gender in the Korean elderly. Methods: Cross-sectional data from the Seventh (2016–2018) Korea National Health and Nutrition Examination...
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Anti-Alpha-Toxin Antibody Responses and Clinical Outcomes of Staphylococcus aureus Bacteremia

Kim NH, Choi Y, Kwon K, Park JS, Park KU, Moon SM, Song KH, Kim ES, Park WB, Kim HB

Background: Alpha-toxin (AT), a major virulence factor of Staphylococcus aureus, is an important immunotherapeutic target to prevent or treat invasive S. aureus infections. Previous studies have suggested that anti-AT antibodies...
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COVID-19 outbreak in a religious village community in Republic of Korea and risk factors for transmission

Shim J, Lee E, Kim E, Choi Y, Kang G, Kim BI

Objectives This study aimed to assess the scale and transmission patterns of coronavirus disease 2019 (COVID-19) in a religious village community in South Korea, to determine the risk factors of...
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Long-term outcomes of liver transplantation using grafts from donors with active hepatitis B virus replication: a multicenter cohort study

Gang S, Choi Y, Lee 2 B, Yoon KC, Hong Sy, Suh S, Han ES, Hong SK, Lee HW, Cho JY, Yi Nj, Lee KW, Suh KS

Purpose: Liver grafts from donors with HBV infection contributed to expanding the donor pool under the hepatitis B immunoglobulin and antiviral agents (nucleos(t)ide analogues) in the HBV-endemic area. We report...
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Posttransplant sequential adrenal and spine metastasis of hepatocellular carcinoma responsive to combined regorafenib and radiotherapy: a case report

Kim JY, Yi NJ, Kim YJ, Chie EK, Kim J, Choi HH, Lee J, Lee S, Hong SY, Lee JM, Hong SK, Choi Y, Lee KW, Suh KS

Adrenal and spinal metastases of hepatocellular carcinoma (HCC) are rare entities with significant morbidity and mortality, particularly after liver transplantation (LT). We report a case of a 49-year-old man who...
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Morphologic Analysis and Classification in Insertion of the Fibularis Tertius Tendon: A Cadaveric Study

Kwon H, Cho J, Choi Y, Park K, Lee M, Kim D, Park SB, Park J

The fibularis tertius muscle originates on the medial surface of the fibula and attaches to the proximal portion of the fifth metatarsal bone. The aim of this study is to...
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A Nationwide Survey on Gastrointestinal Endoscopy Practice Patterns among Pediatric Endoscopists in South Korea

Lee YM, Lee Y, Choi SY, Kim HJ, Hong SJ, Kang Y, Lee EH, Lee KJ, Choi Y, Yi DY, Kim S, Kang B

Purpose: Gastrointestinal (GI) endoscopy is an important tool for diagnosing and treating GI diseases in children. This study aimed to analyze the current GI endoscopy practice patterns among South Korean...
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Rate of and Risk Factors for Loss to Follow Up in HIV-Infected Patients in Korea: The Korea HIV/AIDS Cohort Study

Seong H, Choi Y, Kim M, Kim JH, Song JY, Kim SW, Kim SI, Kim YJ, Park DW, Park B, Choi BY, Choi JY

Background: Owing to antiretroviral therapy (ART), acquired immune deficiency syndrome (AIDS)-related mortality has significantly decreased. Retaining in care is an essential step for human immunodeficiency virus (HIV) care cascade. This...
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Improvement of the intestinal epithelial barrier during laxative effects of phlorotannin in loperamide‑induced constipation of SD rats

 Kim J,  Song H, Choi Y, Jin Y,  Roh Y,  Seol A, Park S, Park J, Kang H,  Hwang D

Background: Disruptions of the intestinal epithelial barrier (IEB) are frequently observed in various digestive diseases, including irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). This study assessed the improvement...
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Impact of Body Mass Index on Survival Depending on Sex in 14,688 Patients with Gastric Cancer in a Tertiary Hospital in South Korea

Jo HH, Kim N, Jang J, Choi Y, Park J, Park YM, Ahn S, Yoon H, Shin CM, Park YS, Lee DH, Oh HJ, Lee HS, Park YS, Ahn SH, Suh YS, Park DJ, Kim HH, Kim JW, Kim JW, Lee KW, Chang W, Park JH, Lee YJ, Lee KH, Kim YH

Background/Aims: The incidence and prognosis of gastric cancer (GC) shows sex difference. This study aimed to evaluate the effect of body mass index (BMI) on GC survival depending on sex. Methods: The...
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The Clinical Course and Prognosis of Patients With Nontuberculous Mycobacterial Pulmonary Disease After Solid Organ Transplantation

Kim JY, Han A, Lee H, Ha J, Lee KW, Suh KS, Yi NJ, Min S, Hong SK, Kim YC, Choi Y, Yim JJ, Kwak N

Background: Due to impaired cell-mediated immunity, solid organ transplantation (SOT) recipients are at increased risk of developing nontuberculous mycobacterial pulmonary disease (NTM-PD). However, the clinical course of NTM-PD in SOT...
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A Standardized Pathology Report for Gastric Cancer: 2nd Edition

Park YS, Kook MC, Kim Bh, Lee HS, Kang DW, Gu MJ, Shin OR, Choi Y, Lee W, Kim H, Song IH, Kim KM, Kim HS, Kang G, Park DY, Jin SY, Kim JM, Choi YJ, Chang HK, Ahn S, Chang MS, Han SH, Kwak Y, Seo AN, Lee SH, Cho MY, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

The first edition of ‘A Standardized Pathology Report for Gastric Cancer’ was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago....
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Erratum to "Synthetic Homoisoflavane Derivatives of Cremastranone Suppress Growth of Colorectal Cancer Cells through Cell Cycle Arrest and Induction of Apoptosis" [Biomol. Ther. 30 (2022) 576-584]

Shin HE, Lee S, Choi Y, Park S, Kwon S, Choi JK, Seo SY, Lee Y

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Long-term Effects of the Eradication of Helicobacter pylori on Metabolic Parameters, Depending on Sex, in South Korea

Park J, Kim N, Kim WS, Lim SH, Choi Y, Jo HH, Ji E, Yoon H, Shin CM, Park YS, Lee DH

Background/Aims: Helicobacter pylori (HP) infection is positively associated with metabolic syndrome (MS). However, the long-term effects of eradication therapy on MS and sex differences have not been thoroughly studied. We...
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Evaluation of component release and oxygen-inhibited layer removal on cytotoxicity of syringe-type bis-acryl composites for provisional restorations

Jiang ES, Choi Y, Lim BS, Park YS, Chung SH

This study aimed to analyze the eluted components of syringe-type bis-acryl composites and to evaluate the effect of removing the oxygen-inhibited layer on cytotoxicity. Four different bis-acryl provisional composite materials-Protemp...
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Effects of Aging and Gender on the Anorectal Function of Healthy Subjects Assessed with Conventional Anorectal Manometry

Kim HJ, Kim N, Choi Y, Lee J, Yoon H, Shin CM, Park YS, Lee DH, Kim HR, Kang SB

Background/Aims: Anorectal functions are influenced by gender and age. This study sought to define the normal anorectal pressure values measured with conventional anorectal manometry (ARM) and to evaluate the effects...
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Immunologic Basis of Type 2 Biologics for Severe Asthma

Sim S, Choi Y, Park HS

Asthma is a chronic airway inflammatory disease characterized by reversible airway obstruction and airway hyperreactivity to various environmental stimuli, leading to recurrent cough, dyspnea, and wheezing episodes. Regarding inflammatory mechanisms,...
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Development and Internal/External Validation of a Prediction Model for Weight Loss Following Gastric Cancer Surgery: A Multicenter Retrospective Study

Park JH, Kong SH, Park DJ, Yang HK, Kim JW, Park KB, Cho I, Hwang SH, Kim DW, Kim SM, Ryu SW, Gong SC, Jung PY, Ryu H, Kim SG, Choi CI, Kim DH, Choi SI, Park JH, Park DJ, Kim GY, Choi Y, Lee HJ

Purpose: To develop an individualized model for predicting the extent of unintentional weight loss following gastrectomy in patients with gastric cancer based on related risk factors and to externally validate...
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Progression of a persisting mesenchymal hamartoma to intrahepatic cholangiocarcinoma 24 years after the initial diagnosis: A case report

Gang S, Choi Y, Lee S, Hong Sy, Suh S, Han ES, Hong SK, Yi NJ, Lee KW, Suh KS

Mesenchymal hamartoma of the liver (MHL) is a rare benign tumor that often presents in early childhood, and it rarely occurs in adulthood. Aberrant development of the portal tract is...
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