J Korean Neurol Assoc.
2009 Feb;27(1):64-67.
Severe Amnestic Dementia With Motor Neuron Disease
- Affiliations
-
- 1Department of Neurology, Pusan National University School of Medicine and Medical Research Institute, Busan, Korea.
- 2Department of Nuclear Medicine, Pusan National University School of Medicine and Medical Research Institute, Busan, Korea.
- 3Department of Neurology, Sungkyunkwan University School of Medicine, Seoul, Korea.
- 4Department of Nuclear Medicine, University of Ulsan College of Medicine, Seoul, Korea. jhlee@amc.seoul.kr
- 5Department of Neurology, University of Ulsan College of Medicine, Seoul, Korea.
Abstract
- Motor neuron disease (MND) and frontotemporal dementia often appear together. We report on a 74-year-old woman who presented with a 18-month history of memory deterioration and MND. Her initial clinical diagnosis was probable Alzheimer's disease (AD) coexisting with MND. We conducted 11C-labeled Pittsburgh Compound-B positron-emission tomography (11C-PIB PET) to discriminate AD from other degenerative dementia, the results from which were negative for amyloid deposition.