J Korean Geriatr Soc.
2010 Mar;14(1):42-47.
A Case of Pseudomembranous Aspergillus Tracheobronchitis in a Patient with Diabetes Mellitus
- Affiliations
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- 1Department of Internal Medicine, University of Ulsan, College of Medicine, Ulsan, Korea. yjjegal@uuh.ulsan.kr
- 2Department of Pathology, University of Ulsan, College of Medicine, Ulsan, Korea.
Abstract
- Aspergillus tracheobronchitis is one form of invasive pulmonary aspergillosis which is characterized by ulcers and pseudomembrane formation in tracheobronchial tree. In Aspergillus tracheobronchitis, the infection is often limited to the mucosa and it accounts for less than 10 percents of invasive disease. Invasive aspergillosis mainly occurs in immunocompromized patients with prolonged neutropenia, advanced AIDS, organ transplantation, high-dose glucocorticoid therapy or cytotoxic therapy although it can occur in less immunocompromised patients, such as after influenza, COPD, old age, and diabetes. We report a case of Aspergillus tracheobronchitis in a 61 year-old patient with diabetes and Child Pugh class A liver cirrhosis. He presented with cough and purulent sputum for 10 days. He was diagnosed by bronchoscopy and successfully treated with antifungal therapy.
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