Tuberc Respir Dis.  2011 Jul;71(1):55-58.

A Case of Pulmonary Alveolar Microlithiasis

Affiliations
  • 1Department of Internal Medicine, Myongji Hospital, Kwandong University College of Medicine, Goyang, Korea. pulmochung@kwandong.ac.kr
  • 2Department of Radiology, Myongji Hospital, Kwandong University College of Medicine, Goyang, Korea.

Abstract

Pulmonary alveolar microlithiasis is a rare disease of unknown etiology that is characterized by the presence of calcific concentrations in the alveolar spaces. The radiographic appearance is pathognomonic. Plain chest radiographs show a white lung or sandstorm lung consisting of fine sand like microcalcifications diffusely scattered throughout both lungs with a higher density at the lung bases. We now report the case of a 67-year-old male whose diagnosis was based on characteristic findings on a chest X-ray and a high-resolution computed tomography scan.

Keyword

Calculi; Pulmonary Alveoli

MeSH Terms

Aged
Calcinosis
Calculi
Genetic Diseases, Inborn
Humans
Lung
Lung Diseases
Male
Pulmonary Alveoli
Rare Diseases
Silicon Dioxide
Thorax
Calcinosis
Genetic Diseases, Inborn
Lung Diseases
Silicon Dioxide

Figure

  • Figure 1 Chest radiographs showed widespread small nodules, diffusely involving both the lungs, and commonly described as "sand storm-like". At admission (C), nodules were much increased compare to previous X-rays (A, B).

  • Figure 2 High-resolution computed tomography revealed bilateral pleural effusions and diffusely distributed calcified micronodules.


Reference

1. Harbitz F. Extensive calcifications of the lungs as distinct disease. Arch Intern Med. 1918. 21:139–146.
2. Thapa R, Ganguly D, Ghosh A. Pulmonary alveolar microlithiasis in siblings. Indian Pediatr. 2008. 45:154–156.
3. Castellana G, Lamorgese V. Pulmonary alveolar microlithiasis. World cases and review of the literature. Respiration. 2003. 70:549–555.
4. Olauson H, Brandenburg V, Larsson TE. Mutation analysis and serum FGF23 level in a patient with pulmonary alveolar microlithiasis. Endocrine. 2010. 37:244–248.
5. Mariotta S, Guidi L, Papale M, Ricci A, Bisetti A. Pulmonary alveolar microlithiasis: review of Italian reports. Eur J Epidemiol. 1997. 13:587–590.
6. Sumikawa H, Johkoh T, Tomiyama N, Hamada S, Koyama M, Tsubamoto M, et al. Pulmonary alveolar microlithiasis: CT and pathologic findings in 10 patients. Monaldi Arch Chest Dis. 2005. 63:59–64.
7. Horvatić Herceg G, Bracić I, Korsić M, Herceg D, Petrović R, Kusacić Kuna S, et al. "Sandstorm" image: bone scintigraphy in pulmonary alveolar microlithiasis. Eur J Nucl Med Mol Imaging. 2009. 36:1353.
8. Pant K, Shah A, Mathur RK, Chhabra SK, Jain SK. Pulmonary alveolar microlithiasis with pleural calcification and nephrolithiasis. Chest. 1990. 98:245–246.
9. Palombini BC, da Silva Porto N, Wallau CU, Camargo JJ. Bronchopulmonary lavage in alveolar microlithiasis. Chest. 1981. 80:242–243.
10. Stamatis G, Zerkowski HR, Doetsch N, Greschuchna D, Konietzko N, Reidemeister JC. Sequential bilateral lung transplantation for pulmonary alveolar microlithiasis. Ann Thorac Surg. 1993. 56:972–975.
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