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Core Elements for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals

Cheong HS, Park KH, Kim HB, Kim SW, Kim B, Moon C, Lee MS, Yoon YK, Jeong SJ, Kim YC, Eun BW, Lee H, Shin JY, Kim Hs, Hwang IS, Park CS, Kwon KT, KSfATTKSoIDKSfHaICaPKSoPIDTKSo

Currently, antimicrobial resistance (AMR) is a major threat to global public health. The antimicrobial stewardship program (ASP) has been proposed as an important approach to overcome this crisis. ASP supports...
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Cell-cell contacts via N-cadherin induce a regulatory renin secretory phenotype in As4.1 cells

Chang JW, Kim S, Lee EY, Leem CH, Kim SH, Park CS

The lack of a clonal renin-secreting cell line has greatly hindered the investigation of the regulatory mechanisms of renin secretion at the cellular, biochemical, and molecular levels. In the present...
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Efficient Anti-Tumor Immunotherapy Using Tumor Epitope-Coated Biodegradable Nanoparticles Combined With Polyinosinic-Polycytidylic Acid and an Anti-PD1 Monoclonal Antibody

Kim SH, Park JH, Lee SJ, Lee HS, Jung JK, Lee YR, Cho HI, Kim JK, Kim K, Park CS, Lee CK

Vaccination with tumor peptide epitopes associated with MHC class I molecules is an attractive approach directed at inducing tumor-specific CTLs. However, challenges remain in improving the therapeutic efficacy of peptide...
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The Significance of p-AKT1 as a Prognostic Marker and Therapeutic Target in Patients With Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor-2-Positive Early Breast Cancer

Kim JY, Park CS, Jang SK, Seol H, Seong MK, Noh WC, Park IC, Kim HA

Purpose: Phosphorylated AKT1 (p-AKT1) at Ser473 is a functional isoform of AKT and a key component of the PI3K/mTOR/AKT pathway. This study aimed to evaluate the prognostic significance of p-AKT1...
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Anaphylaxis to Chlorhexidine-Impregnated Central Venous Catheters in Spine Surgery

Choi BW, Park CS, Kim HJ

Attempts to lower rates of catheter-related bloodstream infection have led to the adoption of chlorhexidine-coated central venous catheters (CVCs) in several orthopedic surgeries. On the other hand, there is still...
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Changing Trends What Patients with Thyroid Cancer Surgery Are Concerned About: Comparison between 2012 and 2020

Lee M, Yun HJ, Park KA, Heo J, Kim H, Lee YS, Chang HS, Park CS

Background and Objectives: Given the major changes in spread of COVID-19 and the contribution of technological innovation, the objective of the current study was to compare the educational needs of...
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Surgical Outcomes of Cor Triatriatum Sinister: A Single-Center Experience

Kim D, Kwon BS, Kim DH, Choi ES, Yun TJ, Park CS

Background: We investigated surgical outcomes after the surgical repair of cor triatriatum sinister (CTS). Methods: Thirty-two consecutive patients who underwent surgical repair of CTS from 1993 through 2020 were included in...
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Association Between Clinical Burden and Blood Eosinophil Counts in Asthma: Findings From a Korean Adult Asthma Cohort

Kim MY, Jo EJ, Kim S, Kim MH, Jung JW, Kim JH, Moon JY, Kwon JW, Lee JH, Park CS, Jin HJ, Shin YS, Kim SH, Cho YJ, Park JW, Cho SH, Kim TB, Park HK

Background: Some reports have suggested that the clinical and economic burdens of asthma are associated with blood eosinophil levels. The association between clinical burden and blood eosinophil counts were evaluated...
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Computer-Aided Diagnosis Parameters of Invasive Carcinoma of No Special Type on 3T MRI: Correlation with Pathologic Immunohistochemical Markers

Jeong J, Park CS, Lee JW, Kim K, Kim HS, Jun SY, Oh SJ

Purpose To investigate the correlation between computer-aided diagnosis (CAD) parameters in 3-tesla (T) MRI and pathologic immunohistochemical (IHC) markers in invasive carcinoma of no special type (NST). Materials and Methods A...
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Induction of Peptide-specific CTL Activity and Inhibition of Tumor Growth Following Immunization with Nanoparticles Coated with Tumor Peptide-MHC-I Complexes

Kim SH, Park HE, Jeong SU, Moon JH, Lee YR, Kim JK, Kong H, Park CS, Lee CK

Tumor peptides associated with MHC class I molecules or their synthetic variants have attracted great attention for their potential use as vaccines to induce tumor-specific CTLs. However, the outcome of...
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Erratum to “Effects of Ammonium Chloride on Ozone-induced Airway Inflammation: the Role of Slc26a4 in the Lungs of Mice”

Lee JU, Lee HJ, Kim JN, Kim MK, Kim SR, Chang HS, Park CS, Park JS

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Outcomes after Extracorporeal Membrane Oxygenation in Neonates with Congenital Diaphragmatic Hernia: A SingleCenter Experience

Choi W, Cho WC, Choi ES, Yun TJ, Park CS

Background: Congenital diaphragmatic hernia (CDH) is a rare disease often requiring mechanical ventilation after birth. In severe cases, extracorporeal membrane oxygenation (ECMO) may be needed. This study analyzed the outcomes...
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Sophora flavescens Extracts Have Therapeutic Effects on Overactive Bladder Syndrome by Potentiation of Large-Conductance Calcium-Activated Potassium Channel

Jo H, Lee HJ, Jang SJ, Moh SH, Cheong JH, Park CS

Sophora flavescens Ait. (Fabaceae) is a medicinal plant widely founded in Northeast Asia, and its dried root (Kushen) has been used as a traditional Chinese herbal medicine. The therapeutic effects...
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Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution

Kim M, Hwang HS, Cho H, Yoon DH, Suh C, Park CS, Go H, Huh J

Background: Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in...
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Effect of omalizumab as add-on therapy to Quality of Life Questionnaire for Korean Asthmatics (KAQLQ) in Korean patients with severe persistent allergic asthma

Jung JW, Park HS, Park CS, Cho SH, Choi IS, Moon HB, Kwon SS, Yoon HJ, Park JW, Lee JM, Choi DC, Choi BW

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Preliminary Results of Teleconsultations Temporarily Allowed during the COVID-19 Pandemic

Kim H, Lee H, Park CS, Kim S, Cho SA, Yoo SM, Kim JA, Lee JY

Purpose: During the COVID-19 pandemic, Korea has temporarily expanded coverage of teleconsultation to ensure access to essential health services. As a preliminary study, we investigated service utilization patterns and the...
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Aquagenic Urticaria Treated with Omalizumab

Ha YJ, Jung SY, Lee SG, Park CS

Aquagenic urticaria is a rare form of physical urticaria in which a 1-2 mm wheal is produced by contact with water. Treatment options include antihistamines, ultraviolet monotherapy, topical barrier creams,...
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The Relationship of Pre-Clerkship Immature Defense Style in Medical Students with Physician-Patient Interactions

Lee SJ, Park CS, Kim BJ, Lee CS, Cha B, Lee D, Seo J, Choi JW, Lee YJ, Lee YJ, Lim EJ

Objectives: The ability of medical students to form positive relationships with patients is influenced by the students’ personality.The psychological characteristics necessary for effective physician-patient interactions (PPIs) have not been identified....
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Effect of omalizumab as add-on therapy to Quality of Life Questionnaire for Korean Asthmatics (KAQLQ) in Korean patients with severe persistent allergic asthma

Jung JW, Park HS, Park CS, Cho SH, Choi IS, Moon HB, Kwon SS, Yoon HJ, Park JW, Lee JM, Choi DC, Choi BW

Background/Aims: Omalizumab is the first biologic known to be effective in patients with severe allergic asthma. Methods: This study was conducted as a multicenter, single-group, open trial to evaluate the improvement...
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Prognostic Stratification of Patients with Burkitt Lymphoma Using Serum β2-microglobulin Levels

Kim HD, Cho H, Kim S, Lee K, Kang EH, Park JS, Park CS, Huh J, Ryu JS, Lee SW, Yoon DH, Kim SJ, Ko YH, Kim WS, Suh C

Purpose We aimed to investigate the prognostic value of serum β2-microglobulin for patients with Burkitt lymphoma (BL) and to propose a risk-stratifying classification system. Materials and Methods A prospective registry-based cohort...
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