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A Novel De Novo Pathogenic Variant in FOXF1 in a Newborn with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins

Ma Y, Jang MA, Yoo HS, Ahn SY, Sung SI, Chang YS, Ki CS, Park WS

Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is an autosomal dominant, fatal developmental disorder of the lungs, with a mortality rate of about 100%. ACD/MPV is caused by...
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Malignant Hypertension with Pulmonary Alveolar Hemorrhage Needing Dialysis

Kim Y, Bang KT, Shin JH, Kim JR, Kim JH, Jeong JU

A 35-year-old man presented with progressive dyspnea and hemoptysis. His blood pressure was 230/140 mmHg and serum creatinine level was 20.13 mg/dL. Chest radiography and computed tomography revealed pulmonary hemorrhage....
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Deferoxamine Improves Alveolar and Pulmonary Vascular Development by Upregulating Hypoxia-inducible Factor-1alpha in a Rat Model of Bronchopulmonary Dysplasia

Choi CW, Lee J, Lee HJ, Park HS, Chun YS, Kim BI

Fetal lung development normally occurs in a hypoxic environment. Hypoxia-inducible factor (HIF)-1alpha is robustly induced under hypoxia and transactivates many genes that are essential for fetal development. Most preterm infants...
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Effects of Alveolar Recruitment and Positive End-Expiratory Pressure on Oxygenation during One-Lung Ventilation in the Supine Position

Choi YS, Bae MK, Kim SH, Park JE, Kim SY, Oh YJ

PURPOSE: Hypoxemia during one-lung ventilation (OLV) remains a serious problem, particularly in the supine position. We investigated the effects of alveolar recruitment (AR) and positive end-expiratory pressure (PEEP) on oxygenation...
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Sandstorm Appearance of Pulmonary Alveolar Microlithiasis Incidentally Detected in a Young, Asymptomatic Male

Ch'ng LS, Bux SI, Liam CK, Rahman NA, Ho CY

Pulmonary alveolar microlithiasis (PAM) is a rare chronic disease with paucity of symptoms in contrast to the imaging findings. We present a case of a 24-year-old Malay man having an...
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Diffuse Alveolar Hemorrhage

Park MS

Diffuse alveolar hemorrhage (DAH) is a life-threatening and medical emergency that can be caused by numerous disorders and presents with hemoptysis, anemia, and diffuse alveolar infiltrates. Early bronchoscopy with bronchoalveolar...
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Characteristics of Duffy Blood Group Antigens and Their Global Distribution

Lim CS, Kim KH

  • KMID: 1424261
  • Korean J Blood Transfus.
  • 2013 Apr;24(1):13-20.
The Duffy antigen was discovered in 1950, in a multiply transfused hemophiliac. Important progress has since been made in understanding the Duffy blood group system and its complexity. The Duffy...
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A case of diffuse alveolar hemorrhage after tonsillectomy: A case report

Kim JP, Park JJ, Kim NJ, Woo SH

Diffuse alveolar hemorrhage (DAH) is an acute, life-threatening event. The blood-gas barrier must be very thin to allow gas exchange and is therefore subjected to high mechanical stresses when the...
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Effects of Postnatal Dexamethasone or Hydrocortisone in a Rat Model of Antenatal Lipopolysaccharide and Neonatal Hyperoxia Exposure

Lee HJ, Kim BI, Choi ES, Choi CW, Kim EK, Kim HS, Choi JH

The aim of our study was to investigate the differential effects of dexamethasone (DXM) and hydrocortisone (HCS) on somatic growth and postnatal lung development in a rat model of bronchopulmonary...
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A Case of Pulmonary Alveolar Microlithiasis

Kang HW, Kim TO, Oh IJ, Kim YI, Lim SC, Choi YD, Song SY, Seon HJ, Kwon YS

Pulmonary alveolar microlithiasis (PAM) is a rare disease with unknown etiology and pathogenesis. It is characterized by diffuse, innumerable, and minute calculi, called microlithiasis in the alveoli. More than half...
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Inhibitory effect of receptor for advanced glycation end products (RAGE) on the TGF-beta-induced alveolar epithelial to mesenchymal transition

Song JS, Kang CM, Park CK, Yoon HK, Lee SY, Ahn JH, Moon HS

Idiopathic pulmonary fibrosis (IPF) is a lethal parenchymal lung disease characterized by myofibroblast proliferation. Alveolar epithelial cells (AECs) are thought to produce myofibroblasts through the epithelial to mesenchymal transition (EMT)....
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A Case of Pulmonary Alveolar Microlithiasis

Lee BH, Kang BS, Min JW, Park SJ, Kim TH, Chung JH, Park CS

  • KMID: 2319547
  • Tuberc Respir Dis.
  • 2011 Jul;71(1):55-58.
Pulmonary alveolar microlithiasis is a rare disease of unknown etiology that is characterized by the presence of calcific concentrations in the alveolar spaces. The radiographic appearance is pathognomonic. Plain chest...
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Cathepsin B is activated as an executive protease in fetal rat alveolar type II cells exposed to hyperoxia

Lee HS, Kim CK

Alveolar type II cells are main target of hyperoxia-induced lung injury. The authors investigated whether lysosomal protease, cathepsin B (CB), is activated in fetal alveolar type II cells in the...
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Clinical Features and Outcomes of Microscopic Polyangiitis in Korea

Oh JS, Lee CK, Kim YG, Nah SS, Moon HB, Yoo B

Microscopic polyangiitis (MPA) is a systemic vasculitis affecting small vessels. To determine the clinical features and outcomes of MPA in Korean patients, we retrospectively reviewed the medical records of patients...
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A Case of Adult-Onset Still's Disease Complicated with Diffuse Alveolar Hemorrhage

Sari I, Birlik M, Binicier O, Akar S, Yilmaz E, Onen F, Akkoc N

Adult-onset Still's disease (AOSD) is an inflammatory disease that presents with a variety of clinical symptoms. Pulmonary involvement is well-known in AOSD and is seen in up to 53% of...
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Comment on: A Case of Post-streptococcal Glomerulonephritis with Diffuse Alveolar Hemorrhage

Shin JI, Lee JS

No abstract available.
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A Case of Post-Streptococcal Glomerulonephritis with Diffuse Alveolar Hemorrhage

Sung HY, Lim CH, Shin MJ, Kim BS, Kim YO, Song HC, Kim SY, Choi EJ, Chang YS, Bang BK

Acute post-streptococcal glomerulonephritis (PSGN) is characterized by an abrupt onset of edema, hypertension, and hematuria. Life-threatening diffuse alveolar hemorrhage (DAH) is rarely associated with acute PSGN. There have been only...
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TACI:Fc scavenging B cell activating factor (BAFF) alleviates ovalbumin-induced bronchial asthma in mice

Moon EY, Ryu SK

  • KMID: 1047085
  • Exp Mol Med.
  • 2007 Jun;39(3):343-352.
Asthma was induced by the sensitization and challenge with ovalbumin (OVA) in mice. B-cell activating factor (BAFF) plays a role in mature B cell generation and maintenance. Here, we investigated...
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Primary Alveolar Soft Part Sarcoma of the Lung

Kim YD, Lee CH, Lee MK, Jeong YJ, Kim JY, Park DY, Sol MY

Alveolar soft part sarcoma (ASPS) is a rare epithelial-like soft tissue sarcoma. The two main sites of its occurrence are the lower extremities in adults and the head and neck...
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Diffuse Alveolar Hemorrhage Associated with Antineutrophil Cytoplasmic Antibody levels in a Pregnant Woman Taking Propylthiouracil

Kang AY, Baek YH, Sohn YJ, Lee SK, Son CH, Kim K, Yang DK

Propylthiouracil (PTU) is known to be a potential cause of antineutrophil cytoplasmic antibody (ANCA) positive small vessel vasculitis, resulting in glomerulonephritis and diffuse alveolar hemorrhage (DAH). Herein, we describe a...
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