Restor Dent Endod.  2014 Aug;39(3):230-234.

The use of platelet rich plasma in the treatment of immature tooth with periapical lesion: a case report

• Guven Polat G
• Yildirim C
• Akgun OM
• Altun C
• Dincer D
• Ozkan CK

Abstract

This study describes the treatment of an immature permanent tooth with periapical lesion which was treated with regenerative approach using platelet rich plasma (PRP). The root canal of immature human permanent tooth with periapical lesion was gently debrided of necrotic tissue and disinfected with 2.5% NaOCl, and then medicated with triple antibiotic paste comprised of ciprofloxacin, metronidazole, and tetracycline. When the tooth was asymptomatic, PRP and mineral trioxide aggregate (MTA) were placed into the root canal. Six months after PRP treatment, radiographical examination revealed resolution of the radiolucency and progressive thickening of the root wall and apical closure. Our findings suggest that PRP can be used for the treatment of immature permanent teeth with periapical lesion, as part of a regenerative endodontic treatment procedure.

Keyword

Immature permanent tooth; Periapical lesions; Platelet rich plasma

MeSH Terms

Ciprofloxacin
Dental Pulp Cavity
Humans
Metronidazole
Platelet-Rich Plasma*
Tetracycline
Tooth*
Ciprofloxacin
Metronidazole
Tetracycline

Figure

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  Figure 1 Periapical radiograph of the left permanent mandibular second premolar before treatment.

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  Figure 2 Immediate post-operative periapical radiograph of the left permanent mandibular second premolar.

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  Figure 3 Periapical radiograph of the left permanent mandibular second premolar six months after treatment.

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  Figure 4 Periapical radiograph of the left permanent mandibular second premolar two years after treatment.

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