Pediatr Gastroenterol Hepatol Nutr.  2012 Mar;15(1):23-28.

Clinical and Endoscopic Findings in Children with Peptic Ulcer in Terms of Helicobacter pylori in Incheon

• Cho SH
• Chun KY
• Ryoo E
• Kim YS
• Tchah H

Abstract

PURPOSE
Interest in peptic ulcer in children has been relatively low because the disease is rarer in children than in adults and there were restrictions in the application of endoscopy to children, but the recent development of pediatric endoscopy is activating research on pediatric peptic ulcer. Thus, this study compared the H. pylori infection rate and clinical and endoscopic findings among pediatric patients diagnosed with peptic ulcer.
METHODS
We analyzed retrospectively 58 pediatric patients for whom whether to be infected with H. pylori was confirmed selected out of pediatric patients diagnosed with gastric ulcer or duodenal ulcer through upper gastrointestinal endoscopy at the Department of Pediatrics of Gachon University Gil Hospital during the period from January 2002 to December 2007. A case was considered H. pylori positive if H. pylori was detected in the Giemsa stain of tissue or the results of UBT (urea breath test) and CLO (rapid urease test) were both positive.
RESULTS
Of the pediatric patients, 37 were infected with H. pylori and 21 were not. The H. pylori infection rate increased with aging and the result was statistically significant (p<0.05). However, H. pylori infection was not in a statistically significant correlation with sex, chief complaint, and gastroduodenal ulcer (p>0.05).
CONCLUSION
H. pylori infection increased with aging, but was not significantly correlated with gastroduodenal ulcer. Further research may need to examine prospectively the relation between H. pylori and gastroduodenal ulcer in the Incheon area.

Keyword

H. pylori; Gastric ulcer; Duodenal ulcer; Peptic ulcer; Children

MeSH Terms

Adult
Aging
Azure Stains
Child
Duodenal Ulcer
Endoscopy
Endoscopy, Gastrointestinal
Helicobacter
Helicobacter pylori
Humans
Pediatrics
Peptic Ulcer
Retrospective Studies
Stomach Ulcer
Urease
Azure Stains
Urease

Figure

• 

  Fig. 1 Age distribution in terms of H. pylori infection.

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