Nutr Res Pract.  2012 Jun;6(3):208-212.

Effects of adlay, buckwheat, and barley on transit time and the antioxidative system in obesity induced rats

• Kim JY
• Son BK
• Lee SS

Abstract

In the present study, we examined whether four grains including adlay (AD), buckwheat (BW), glutinous barley (GB), and white rice (WR) affect the duration of food residence in the gastrointestinal tract and hepatic enzyme activities in rats fed different combinations of the grains. The rats were raised for 4 weeks on a high fat diet based on the American Institute of Nutrition-93 (AIN-93G) diets containing 1% cholesterol and 20% dietary lipids. Forty male rats were divided into four groups and raised for 4 weeks with a diet containing one of the grains. Corresponding to the dietary fiber contents of the experimental grains, gut transit time was shortest in the rats fed GB and increased in the order of BW, AD, and WR. In addition, the accumulated shortest transit time occurred in the GB group. Gut transit time affected weight gain and major organ weight, as it was closely related to the absorption of nutrients. The level of thiobarbituric acid reactive substance (TBARS) in liver was higher in rats fed WR, AD, BW, and GB, indicating that the other grains decreased oxidative stress in vivo more than WR. Glutathione, glutathione peroxidase, and glutathione S-transferase levels in the AD, BW, and GB groups were significantly higher than those in the WR group. In conclusion, reduced colonic transit time has been implicated in reducing the incidence of colon cancer, as evidenced by populations consuming diets rich in fiber. Whole grains such as AD, BW, and GB may contribute to a significant supply of antioxidants to prevent oxidative stress if they are consumed in large amounts.

Keyword

Adlay; buckwheat; glutinous barley; transit time; antioxidant enzfymes

MeSH Terms

Absorption
Animals
Antioxidants
Edible Grain
Cholesterol
Colon
Colonic Neoplasms
Diet
Diet, High-Fat
Dietary Fiber
Fagopyrum
Gastrointestinal Tract
Glutathione
Glutathione Peroxidase
Glutathione Transferase
Hordeum
Humans
Incidence
Liver
Male
Obesity
Organ Size
Oxidative Stress
Rats
Thiobarbiturates
Weight Gain
Antioxidants
Cholesterol
Glutathione
Glutathione Peroxidase
Glutathione Transferase
Thiobarbiturates

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