Korean J Helicobacter Up Gastrointest Res.  2014 Mar;14(1):61-66. 10.7704/kjhugr.2014.14.1.61.

A Case of Multiple Primary Cancer with Follicular Lymphoma

• Park CS
• Lee SH
• Kim SB
• Park JS
• Kim SJ
• Park JM
• Kang SH

• KMID: 2305157
• DOI: http://doi.org/10.7704/kjhugr.2014.14.1.61

Abstract

The incidence of multiple primary cancer (MPC) is low but has been reported occasionally. Although follicular lymphoma is rare in Korea, the incidence is reported to be gradually increasing. We report a case of synchronous and metachronous MPC consisting of esophagus (squamous cell carcinoma), stomach (adenocarcinoma), and ampulla of Vater (extranodal follicular lymphoma grade 1) in a patient diagnosed as follicular lymphoma (grade 3a) six years ago. In a complicated case like ours, concurrent therapeutic control of synchronous MPC and metachronous hematological malignancy is challenging; meticulous examination and prioritized target therapy are essential for patients' survival.

Keyword

Multiple primary cancer; Squamous cell carcinoma; Adenocarcinoma; Follicular lymphoma

MeSH Terms

Adenocarcinoma
Ampulla of Vater
Carcinoma, Squamous Cell
Esophagus
Hematologic Neoplasms
Humans
Incidence
Korea
Lymphoma, Follicular*
Stomach