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Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis Resembling Recurrent Follicular Lymphoma: A Case Report

Park CH, Choi YB

Epstein-Barr virus (EBV)-associated lymphoproliferative diseases represent various clinical manifestations. EBV-associated hemophagocytic lymphohistiocytosis (HLH) and lymphoma are difficult to distinguish due to overlapping characteristics between these two diseases. Here, we present...
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Primary non-Hodgkin lymphoma of the parotid gland: a case report

Ryoo HJ, Lim JS, Kim MC

Most malignant lymphomas of the head and neck region are non-Hodgkin lymphomas (NHL), and diffuse large B-cell lymphoma is the most common subtype. The prevalence of malignant lymphoma among parotid...
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A Rare Case of Primary Duodenal Follicular Lymphoma

Kim HJ, Choi J

Primary duodenal follicular lymphoma is rare and presents as multiple, small polyp-like lesions on endoscopy. If this lesion is suspected, an endoscopic biopsy is crucial for diagnosis. A watchful wait...
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Treatment of indolent lymphoma

Jeong SH

Treatment of indolent lymphoma has improved significantly in recent decades since the advent of rituximab (anti-CD20 monoclonal antibody). Although, some patients with limited disease can be cured with radiation therapy...
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Primary Gastrointestinal Follicular Lymphomas: A Prospective Study of 31 Patients with Long-term Follow-up Registered in the French Gastrointestinal Lymphoma Study Group (GELD) of the French Federation of Digestive Oncology (FFCD)

Matysiak-Budnik T, Jamet P, Chapelle N, Fabiani B, Coppo P, Ruskoné-Fourmestraux A

Background/Aims: Primary gastrointestinal follicular lymphomas (PGFL) are very rare. Our aim was to analyze the clinical features, management, and long-term outcomes in a prospective series of patients diagnosed with PGFL. Methods:...
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Follicular lymphoma: updates for pathologists

Khanlari M, Chapman JR

Follicular lymphoma (FL) is the most common indolent B-cell lymphoma and originates from germinal center B-cells (centrocytes and centroblasts) of the lymphoid follicle. Tumorigenesis is believed to initiate early in...
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Composite follicular lymphoma and classic Hodgkin lymphoma

Kim HN, Jeon MJ, Yu ES, Kim DS, Choi CW, Ko YH

Composite lymphoma is very rare and a combination of Hodgkin lymphoma and non-Hodgkin lymphoma and even histiocytic tumors can occur. Because of the unfamiliarity, not only can this cause diagnostic...
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Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution

Kim M, Hwang HS, Cho H, Yoon DH, Suh C, Park CS, Go H, Huh J

Background: Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in...
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A Case of Paraneoplastic Pemphigus as a Preceding Manifestation of Underlying Follicular Lymphoma Treated with R-CHOP

Kim M, Lee JY, Kim SC, Na JI

Paraneoplastic pemphigus is a rare, life-threatening disorder associated with an underlying neoplasm, which presents with painful stomatitis and polymorphous skin lesions. Successful diagnosis of paraneoplastic pemphigus can lead to the...
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A Case of Pediatric Follicular Lymphoma in the Parotid Gland

Kim HR, Jeong JY, Kim YS, Tae K

Pediatric follicular lymphoma (PFL) is rare, and it has distinctive characteristics compared to adult-type follicular lymphoma. PFL mainly occurs in males and is likely to be localized to cervical lymph...
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First report of the unique expression of RECAF (receptor for alfa feto-protein) in adult B-NHL/CLL patients

Adel Sedky H, Youssef SR, Gamal DA, Houssein HF, Elsalakawy WA

Background Lymphoproliferative disorders (LPDs) are a heterogeneous group of diseases characterized by an uncontrolled production of monoclonal lymphocytes. RECAF is the receptor for alpha-fetoprotein, which is re-expressed on malignant cells, thus...
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Morphologic variant of follicular lymphoma reminiscent of hyaline-vascular Castleman disease

Koh J, Jeon YK

Follicular lymphoma (FL) with hyaline-vascular Castleman disease (FL-HVCD)-like features is a rare morphologic variant, with fewer than 20 cases in the literature. Herein, we report a case of FL-HVCD in...
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Prognostic Value of Baseline and Interim Total Metabolic Tumor Volume and Total Lesion Glycolysis Measured on ¹⁸F-FDG PET-CT in Patients with Follicular Lymphoma

Liang JH, Zhang YP, Xia J, Ding CY, Wu W, Wang L, Cao L, Zhu HY, Fan L, Li TN, Li JY, Xu W

PURPOSE: The purpose of this study was to investigate the prognostic significance of total metabolic tumor volume (TMTV) and total lesion glycolysis (TLG) in patients with follicular lymphoma (FL) at...
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Predictive Value of Interim and End-of-Therapy 18F-FDG PET/CT in Patients with Follicular Lymphoma

Boo SH, O JH, Kwon SJ, Yoo IR, Kim SH, Park GS, Choi BO, Jung SE, Cho SG

PURPOSE: ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is the standard imaging modality for response evaluation in FDG-avid lymphoma, but the prognostic value is not established in follicular lymphoma (FL)....
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Radiation Therapy Outcome and Clinical Features of Duodenal-Type Follicular Lymphoma

Lee H, Oh D, Yang K, Ko YH, Ahn YC, Kim WS, Kim SJ

PURPOSE: Duodenal-type follicular lymphoma (FL) is a rare variant of FL. There is still no consensus on the initial treatment, and clinical features including endoscopic findings are not familiar to...
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Pediatric follicular lymphoma of the parotid gland

Choi J, Choi HJ, Yim K, Kwon H, Byeon JH, Jung SN

Primary malignant lymphoma rarely presents as a mass in the salivary gland. It accounts for about 1% of salivary gland tumors. The lymphomas of the parotid gland are mainly non-Hodgkin's...
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Gastric Follicular Lymphomas Presenting as Subepithelial Tumors: Two Cases

Kim HJ, Choi CW, Park SB, Kim SJ

Follicular lymphoma is the most common form of low-grade B cell lymphoma. Follicular lymphoma occurs predominantly at lymph node sites and rarely in the gastrointestinal tract. Rare gastrointestinal follicular lymphoma...
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Primary Follicular Lymphoma in the Rectum Incidentally Found on Screening Colonoscopy

Pyeon SI, Song GA, Baek DH, Kim GH, Lee BE, Lee SJ, Yoon JB, Han SY, Park DY

The gastrointestinal tract is the most common site of extra-nodal non-Hodgkin lymphoma. However, the incidence of primary rectal lymphoma is extremely rare. Among the primary gastrointestinal lymphomas, follicular lymphoma has...
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Treatment outcomes and clinical relevance of the Follicular Lymphoma International Prognostic Index in Korean follicular lymphoma patients treated with chemotherapy

Maeng CH, Ahn SW, Ryu SY, Han S, Ko YH, Ji JH, Kim WS, Kim SJ

BACKGROUND/AIMS: The Follicular Lymphoma International Prognostic Index (FLIPI) and FLIPI2 are well-known prognostic models for patients with follicular lymphoma (FL). However, their prognostic relevance has not been examined before in...
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Radiotherapy as an effective treatment modality for follicular lymphoma: a single institution experience

Choi SH, Cho J, Kim JS, Cheong JW, Suh CO

PURPOSE: Follicular lymphoma (FL) is an indolent non-Hodgkin's lymphoma that is highly sensitive to radiotherapy (RT). However, the effectiveness of RT has not been well established. We reviewed our experiences...
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