Ann Dermatol.  1999 Apr;11(2):124-128. 10.5021/ad.1999.11.2.124.

A Case of Primary Cutaneous Marginal Zone B-cell Lymphoma

Abstract

We herein present a rare case of a 42-year-old man with primary cutaneous marginal zone lymphoma(MZL) of the B-cell type on his shin. MZL is known to be the cutaneous counterpart of MALT(mucosa-associated lymphatic tissue) lymphoma. Histopathologically, MZL is characterized by multi-nodular infiltrates of centrocyte-like and centroblast-like marginal cells with bottom-heavy patterns, lymphoplasmacytoid differentiation, typical distribution of tumor cells in the marginal zone and follicular colonization by tumor cells. This B-cell lymphoma of a benign grade should be differentiated from mantle cell lymphoma and follicular center cell lymphoma.

Keyword

Primary cutaneous marginal zone lymphoma

MeSH Terms

Adult
B-Lymphocytes
Colon
Humans
Lymphoma
Lymphoma, B-Cell
Lymphoma, B-Cell, Marginal Zone*
Lymphoma, Mantle-Cell
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