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Imbalance in the spinal serotonergic pathway induces aggravation of mechanical allodynia and microglial activation in carrageenan inflammation

Jin J, Kang DH, Jeon J, Lee HG, Kim WM, Yoon MH, Choi JI

Background: This study investigated the effect of an excess and a deficit of spinal 5-hydroxytryptamine (5-HT) on the mechanical allodynia and neuroglia activation in a rodent pain model of carrageenan...
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Vertebral Artery Dissecting Aneurysm Causing Central Tapia’s Syndrome: A Case Report

Shim YW, Park JH, Kim ST, Baek JW, Lee HG, Ko JH, Paeng SH, Pyo SY, Jin SC, Jeong HW, Jeong YG

The central type of Tapia’s syndrome is an extremely rare presentation, characterized by unilateral paralysis of the vagal and hypoglossal nerves, contralateral hemiparesis, or hemihypesthesia. This report describes a case...
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Protective Effects of Silibinin on Helicobacter pyloriinduced Gastritis: NF-κB and STAT3 as Potential Targets

Cho K, Lee HG, Piao JY, Kim SJ, Na HK, Surh YJ

More than half of the world’s populations are considered to be infected by Helicobacter pylori. It causes a chronic inflammation of the stomach, which is implicated in the pathogenesis of...
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A Rare Case of Pulmonary Arteriovenous Malformation Caused by Hereditary Hemorrhagic Telangiectasia in a Hemodialysis Patient

Bahk S, Bu SH, Kim HD, Won Y, Lee HG, Kim YO

Hereditary hemorrhagic telangiectasia (HHT) is an uncommon autosomal dominant disorder resulting in vascular malformation, such as pulmonary arteriovenous malformation (PAVM). Here, we report a rare case of pulmonary arteriovenous malformation...
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Systemically administered neurotensin receptor agonist produces antinociception through activation of spinally projecting serotonergic neurons in the rostral ventromedial medulla

Li Y, Kang DH, Kim WM, Lee HG, Kim SH, You HE, Choi JI, Yoon MH

Background: Supraspinal delivery of neurotensin (NTS), which may contribute to the effect of a systemically administered agonist, has been reported to be either pronociceptive or antinociceptive. Here, we evaluated the...
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Prostaglandin D2 contributes to cisplatin-induced neuropathic pain in rats via DP2 receptor in the spinal cord

Li Y, Kim WM, Kim SH, You HE, Kang DH, Lee HG, Choi JI, Yoon MH

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a major reason for stopping or changing anticancer therapy. Among the proposed pathomechanisms underlying CIPN, proinflammatory processes have attracted increasing attention. Here we assessed...
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Treatment outcome and prognostic factors of Korean patients with chronic lymphocytic leukemia: a multicenter retrospective study

Choi Y, Lee JH, Jung CW, Jo JC, Kim ,JS, Kim I, Park S, Cheong Jw, Park SH, Kim SY, Lee HG

Background/Aims Compared with Western countries, chronic lymphocytic leukemia (CLL) rarely occurs in Asia and has different clinical characteristics. Thus, we aimed to evaluate the clinical characteristics, treatment outcomes, and prognostic significance...
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Technical and Clinical Considerations for Successful Management of Postoperative Bowel Perforation by Percutaneous Foley Catheter Placement

Cho Sy, Oh JS, Lee HG, Choi BG

Purpose: The aim of this study was to analyze several technical and clinical factors associated with the successful management of postoperative leakage by percutaneous Foley catheter placement. Materials and Methods: Thirty-two...
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Structural Analysis of the Health Related Quality of Life in Working Women with Preschool Children

Lee HG, Kim SH

Purpose: The purpose of this study was to construct a model that describes the health related quality of life in working women with preschool children and to verify the goodness...
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Herpes zoster in the ophthalmic branch of the trigeminal ganglia obscuring cavernous sinus thrombosis due to Streptococcus constellatus ssp. constellatus

Lee JH, Heo HJ, Kim KM, Lee HG, Baek SM, Jung DW

Background: Herpes zoster ophthalmicus (HZO) is an infectious disease that results from the reactivation of latent varicella zoster virus in the ophthalmic branch of the trigeminal ganglia. HZO manifests with...
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Effect-site concentration of remifentanil for preventing propofol injection pain during induction of balanced anesthesia

Kim J, Kim D, Lee HG

Background: Despite various strategies designed for preventing pain from propofol injection, it is still common and distressing to the patients. The purpose of the present study was to investigate the...
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Comparison of chemical pregnancy rates according to the anesthetic method during ultrasound-guided transvaginal oocyte retrieval for in vitro fertilization: a retrospective study

Heo HJ, Kim YY, Lee JH, Lee HG, Baek SM, Kim KM

Background: Oocyte retrieval is the most important procedure in in vitro fertilization (IVF). Various anesthetic methods are used to control a patient’s anxiety and pain during IVF; however, there are...
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Modulation of Immunosuppression by Oligonucleotide-Based Molecules and Small Molecules Targeting Myeloid-Derived Suppressor Cells

Lim J, Lee A, Lee HG, Lim JS

Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells that exert suppressive function on the immune response. MDSCs expand in tumor-bearing hosts or in the tumor microenvironment and suppress T cell...
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Influence of Secondary Trauma Stress, and Vocation on Turnover Intention of Nurses in Regional Trauma Centers

Lee HG, Kim JS

PURPOSE: This study was done to examine the influence of secondary trauma stress, and vocation on turnover intention of nurses in regional trauma centers. METHODS: For this study a descriptive cross-sectional...
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Curcumin Elevates T(FH) Cells and Germinal Center B Cell Response for Antibody Production in Mice

Kim DH, Lee HG, Choi JM

Curcumin is a natural product extracted from Curcuma longa. It has been reported as a potent antioxidant and anti-inflammatory compound. Previous studies have demonstrated that curcumin suppresses pro-inflammatory cytokine production...
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Antifungal Mechanism of Action of Lauryl Betaine Against Skin-Associated Fungus Malassezia restricta

Do E, Lee HG, Park M, Cho YJ, Kim DH, Park SH, Eun D, Park T, An S, Jung WH

Betaine derivatives are considered major ingredients of shampoos and are commonly used as antistatic and viscosity-increasing agents. Several studies have also suggested that betaine derivatives can be used as antimicrobial...
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Use of Cardiac Computed Tomography and Magnetic Resonance Imaging in Case Management of Atrial Fibrillation with Catheter Ablation

Lee HG, Shim J, Choi JI, Kim YH, Oh YW, Hwang SH

Atrial fibrillation (AF) is the most common arrhythmia associated with the risk of morbidity and mortality in clinical patients. AF is considered as an arrhythmia type that develops and progresses...
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Misdiagnosis of ameloblastoma in a patient with clear cell odontogenic carcinoma: a case report

Park JC, Kim SW, Baek YJ, Lee HG, Ryu MH, Hwang DS, Kim UK

Clear cell odontogenic carcinoma (CCOC), a rare tumor in the head and neck region, displays comparable properties with other tumors clinically and pathologically. In consequence, an incorrect diagnosis may be...
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Refractory intercostal neuralgia due to intercostal schwannoma: A case report

Heo HJ, Kim YY, Lee JH, Im SM, Kim OH, Lee HG

Intercostal neuralgia is neuropathic pain that develops in the thorax and abdomen. It usually occurs as a result of injury or inflammation associated with the intercostal nerve triggered by trauma,...
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Effect of a combination of 2% lidocaine jelly and thermally softened endotracheal tube on postoperative sore throat

Song JA, Lee S, Choi JI, Lee HG, Park SY, Hwang JY, Park S, Jeong S

BACKGROUND: Postoperative sore throat (POST) is a common adverse event after general anesthesia. The aim of this study was to evaluate the effectiveness of 2% lidocaine jelly applied on the...
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