Korean J Health Promot.  2012 Dec;12(4):203-210.

Effects of Acute Aerobic Exercise on Circulating Adiponectin and Inflammatory Makers in Obese Middle-Aged Women

• Lim KI
• Suk MH
• Shin YA

Abstract

BACKGROUND
Exercise intensity may induce changes in inflammatory markers and adipocytokines. However, it is not clear whether acute exercise-induced change to adiponenctin is associated with inflammatory markers and other adipocytokines in obese middle-aged individuals. The aim of this study was to investigate the effects of acute aerobic exercise on circulating adipocytokines and inflammatory markers in obese middle-aged women.
METHODS
Using a crossover design, 10 obese middle-aged women (aged 48.4+/-5.1 years; body mass index 29.6+/-2.9 kg/m2) exercised on the treadmill at different durations and velocities at 60% and 80% maximum oxygen consumption (VO2max) in order to equalize energy expenditure (400 kcal). Blood samples were drawn to measure glucose, insulin, fibrinogen, high-sensitive C-reactive protein, leptin, tumor necrosis factor-alpha (TNF-alpha), and adiponectin concentrations.
RESULTS
Glucose, fibrinogen, and hsCRP increased significantly (P<0.05) after exercise whereas homeostasis model assessment-insulin resistance decreased significantly (P<0.05). Adiponectin, leptin, and TNF-alpha levels did not change significantly at immediate postexercise, and there were also no significant time x intensity interactions for all variables. The percentage change in adiponectin concentration from baseline to the end of exercise correlated with the percentage change in leptin concentration (r=-0.642, P<0.05) with 60% VO2max exercise.
CONCLUSIONS
Our results indicated that, in obese middle-aged women, neither 60% nor 80% VO2max exercise alters adiponectin concentration, in spite of the changes to insulin resistance and inflammatory markers. However, after acute moderate exercise, adiponectin concentration may be associated with the change in leptin levels.

Keyword

Adiponectin; Adipokines; Inflammation; Obesity; Exercise

MeSH Terms

Adipokines
Adiponectin
Body Mass Index
C-Reactive Protein
Cross-Over Studies
Energy Metabolism
Exercise
Female
Fibrinogen
Glucose
Homeostasis
Humans
Inflammation
Insulin
Insulin Resistance
Leptin
Obesity
Oxygen Consumption
Tumor Necrosis Factor-alpha
Adipokines
Adiponectin
C-Reactive Protein
Fibrinogen
Glucose
Insulin
Leptin
Tumor Necrosis Factor-alpha