- Pathophysiology of neuropathic pain
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Kwon O
- KMID: 2518510
- J Korean Med Assoc.
- 2021 Jul;64(7):468-476.
- doi: 10.5124/jkma.2021.64.7.468
Background: Neuropathic pain is notoriously difficult to manage properly, not only because of its varied nature and the absence of objective diagnostic tools but also because of extensive reciprocal neuronal... -
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- The role of inflammation in diabetic kidney disease
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Jung SW, Moon JY
- KMID: 2517794
- Korean J Intern Med.
- 2021 Jul;36(4):753-766.
- doi: 10.3904/kjim.2021.174
Diabetic kidney disease (DKD) has been the leading cause of chronic kidney disease for over 20 years. Yet, over these two decades, the clinical approach to this condition has not... -
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- Intravenous Administration of Toll-Like Receptor Inhibitory Peptide 1 is Effective for the Treatment of Systemic Lupus Erythematosus in a Mus musculus Model
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Baek WY, Lee SM, Lee SW, Son IO, Choi S, Suh CH
- KMID: 2516949
- J Rheum Dis.
- 2021 Jul;28(3):133-142.
- doi: 10.4078/jrd.2021.28.3.133
Objective Systemic lupus erythematosus (SLE) is a common chronic autoimmune inflammatory disease. According to recent studies, signaling through Toll-like receptor (TLR) protein, which promotes the production of inflammatory cytokines, leads... -
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- Wnt-C59 inhibits proinflammatory cytokine expression by reducing the interaction between β-catenin and NF-κB in LPS-stimulated epithelial and macrophage cells
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Jang J, Song J, Sim I, Yoon Y
- KMID: 2516870
- Korean J Physiol Pharmacol.
- 2021 Jul;25(4):307-319.
- doi: 10.4196/kjpp.2021.25.4.307
Dysregulation of the Wnt pathway causes various diseases including cancer, Parkinson’s disease, Alzheimer’s disease, schizophrenia, osteoporosis, obesity and chronic kidney diseases. The modulation of dysregulated Wnt pathway is absolutely necessary.... -
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- Downregulation of MicroRNA-495 Alleviates IL-1β Responses among Chondrocytes by Preventing SOX9 Reduction
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Joung S, Yoon DS, Cho S, Ko EA, Lee KM, Park KH, Lee JW, Kim SH
- KMID: 2516858
- Yonsei Med J.
- 2021 Jul;62(7):650-659.
- doi: 10.3349/ymj.2021.62.7.650
Purpose: Our previous work demonstrated that miRNA-495 targets SOX9 to inhibit chondrogenesis of mesenchymal stem cells. In this study, we aimed to investigate whether miRNA-495-mediated SOX9 regulation could be a novel... -
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- Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches
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Thein W, Po WW, Choi WS, Sohn UD
- KMID: 2517153
- Biomol Ther.
- 2021 Jul;29(4):353-364.
- doi: 10.4062/biomolther.2021.086
The gastrointestinal (GI) tract is a series of hollow organs that is responsible for the digestion and absorption of ingested foods and the excretion of waste. Any changes in the... -
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- Interruption of Helicobacter pylori-Induced NLRP3 Inflammasome Activation by Chalcone Derivatives
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Choi HR, Lim H, Lee JH, Park H, Kim HP
- KMID: 2517159
- Biomol Ther.
- 2021 Jul;29(4):410-418.
- doi: 10.4062/biomolther.2020.192
Helicobacter pylori causes chronic gastritis through cag pathogenicity island (cagPAI), vacuolating cytotoxin A (VacA), lipopolysaccharides (LPS), and flagellin as pathogen-related molecular patterns (PAMPs), which, in combination with the pattern recognition... -
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- Fermented Product Extract with Lentinus edodes Attenuate the Inflammatory Mediators Releases and Free Radical Production
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Shim SY, Lee M
- KMID: 2517553
- Nat Prod Sci.
- 2021 Jun;27(2):115-121.
- doi: 10.20307/nps.2021.27.2.115
Lentinus edodes contains functional metabolites such as polysaccharopeptides, lectins, and secondary metabolites. Fermented soybean paste is representative fermented materials in Korea, and is gradually increasing due to various biological activities.... -
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- Evaluation of cytotoxicity and inflammatory tissue response of mineral trioxide aggregates containing dicalcium phosphate dihydrate
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Park HJ, Park HC, Son G, Kim Y, Wu L, Choi SH, Yang HC
- KMID: 2517508
- Korean J Dent Mater.
- 2021 Jun;48(2):125-134.
- doi: 10.14815/kjdm.2021.48.2.125
The purpose of this study was to evaluate the effect of dicalcium phosphate dihydrate (DCPD) on the biocompatibility of mineral trioxide aggregate (MTA). DCPD was added to MTA (OrthoMTA) to... -
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- Does Obesity Affect the Severity of Exercise-Induced Muscle Injury?
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Kim J, Yoon JH
- KMID: 2517317
- J Obes Metab Syndr.
- 2021 Jun;30(2):132-140.
- doi: 10.7570/jomes20100
This literature review investigates the effects of obesity on exercise-induced muscle injury and reexamines the potential mechanisms of exercise-induced muscle injury related to obesity. Several studies reported that high body... -
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- Blood-brain barrier dysfunction in ischemic stroke and diabetes: the underlying link, mechanisms and future possible therapeutic targets
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Wicha P, Das S, Mahakkanukrauh P
- KMID: 2516900
- Anat Cell Biol.
- 2021 Jun;54(2):165-177.
- doi: 10.5115/acb.20.290
Ischemic stroke caused by occlusion of cerebral artery is responsible for the majority of stroke that increases the morbidity and mortality worldwide. Diabetes mellitus (DM) is a crucial risk factor... -
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- The Role of Upper Airway Microbiome in the Development of Adult Asthma
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Losol P, Choi JP, Kim SH, Chang YS
- KMID: 2518344
- Immune Netw.
- 2021 Jun;21(3):e19.
- doi: 10.4110/in.2021.21.e19
Clinical and molecular phenotypes of asthma are complex. The main phenotypes of adult asthma are characterized by eosinophil and/or neutrophil cell dominant airway inflammation that represent distinct clinical features. Upper... -
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- Association between Depression and hs-CRP Blood Levels in Korean Adults: Using the National Health and Nutrition Survey 2018
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Ahn MH, Eom YJ, Park YK
- KMID: 2516843
- Korean J Fam Pract.
- 2021 Jun;11(3):191-196.
- doi: 10.21215/kjfp.2021.11.3.191
Background: In previous studies, C-reactive protein (CRP), interleukin (IL)-6, and IL-1 increased in depressed patients. Experimental and clinical evidence has reported that inflammatory mediators can induce symptoms of depression. Therefore,... -
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- Association between Electronic Cigarettes, Conventional Cigarettes, and Dual Use and Inflammation and Oxidative Stress: The Seventh Korean National Health and Nutrition Examination Survey 2016–2018
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Seo Hj, Kim Jh, Kim Sa, Shin Wy, Lee Jw, Cho SH
- KMID: 2516842
- Korean J Fam Pract.
- 2021 Jun;11(3):184-190.
- doi: 10.21215/kjfp.2021.11.3.184
Background: The rate of e-cigarette use is increasing due to the perception that there is a smoking cessation effect and that there is relatively low harm; most users use e-cigarettes in... -
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- Do Anxiety and Depression Levels Affect the Inflammation Response in Patients Hospitalized for COVID-19
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Kahve AC, Kaya H, Okuyucu M, Goka E, Barun S, Hacimusalar Y
- KMID: 2517769
- Psychiatry Investig.
- 2021 Jun;18(6):505-512.
- doi: 10.30773/pi.2021.0029
Objective The whole world is still struggling with the COVID-19 pandemic. Inflammation response, thought to be associated with severe illness and death, is an important research topic in COVID-19. Inflammation... -
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- Effects of a mixture of Citri Pericarpium and Scutellariae Radix on acute reflux esophagitis in rats
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Lee JA, Shin MR, Roh SS, Park HJ
- KMID: 2517373
- J Nutr Health.
- 2021 Jun;54(3):321-333.
- doi: 10.4163/jnh.2021.54.3.321
Purpose: Reflux esophagitis is a disease caused by the reflux of stomach contents and stomach acid etc. into the esophagus due to defect in the lower esophageal sphincter and is... -
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- Comparison between 0.1% Nepafenac and 1% Prednisolone Eye Drop in Postoperative Management Following Micro-incisional Cataract Surgery
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Sarkar S, Bardoloi N, Deb AK
- KMID: 2516664
- Korean J Ophthalmol.
- 2021 Jun;35(3):188-197.
- doi: 10.3341/kjo.2020.0135
Purpose: To compare the efficacy of 0.1% nepafenac and 1% prednisolone acetate eye drop in postoperative inflammation control in micro-incisional cataract surgery. Methods: We conducted a prospective, randomized, comparative, single-blind study.... -
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- Effect and Mechanism Study of Sodium Houttuyfonate on Ventilator-Induced Lung Injury by Inhibiting ROS and Inflammation
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Liu Y, Tang G, Li J
- KMID: 2516087
- Yonsei Med J.
- 2021 Jun;62(6):545-554.
- doi: 10.3349/ymj.2021.62.6.545
Purpose: Ventilator-induced lung injury (VILI) is a serious complication of mechanical ventilation (MV) that increases morbidity and mortality of patients receiving ventilator treatment. This study aimed to reveal the molecular... -
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- Predictors of Diagnostic Contributions and Spontaneous Remission of Symptoms Associated with Positron Emission Tomography with Fluorine-18-Fluorodeoxy Glucose Combined with Computed Tomography in Classic Fever or Inflammation of Unknown Origin: a Retrospective Study
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Tsuzuki S, Tsuzuki S, Watanabe A, Watanabe A, Iwata M, Iwata M, Toyama H, Toyama H, Terasawa T, Terasawa T
- KMID: 2516580
- J Korean Med Sci.
- 2021 Jun;36(22):e150.
- doi: 10.3346/jkms.2021.36.e150
Background: In patients with fever or inflammation of unknown origin (fever of unknown origin [FUO] or inflammation of unknown origin [IUO], respectively), expert consensus recommends the use of positron emission... -
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- Treadmill Running Improves Spatial Learning Memory Through Inactivation of Nuclear Factor Kappa B/Mitogen-Activated Protein Kinase Signaling Pathway in Amyloid-β-Induced Alzheimer Disease Rats
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Kim SH, Ko YJ, Kim JY, Sim YJ
- KMID: 2516591
- Int Neurourol J.
- 2021 May;25(Suppl 1):S35-43.
- doi: 10.5213/inj.2142164.082
Purpose: Exercise is known to reduce proinflammatory cytokines production and apoptosis. We investigated the effect of treadmill running on spatial learning memory in terms of activation of nuclear factor kappa... -
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