Korean J Anesthesiol.  1998 Jul;35(1):151-155. 10.4097/kjae.1998.35.1.151.

Influence of Propofol and Enflurane on the Postoperative Nausea & Vomiting after Pediatric Strabismus Surgery

• Yoon MH
• Hong SH
• Kwak SH
• Jeong CY
• Chung SS

• KMID: 2298923
• DOI: http://doi.org/10.4097/kjae.1998.35.1.151

Abstract

INTRODUCTION
Nausea & vomiting are one of the most distressful events after strabismus surgery in pediatric patients. Propofol is known to reduce the incidence of postoperative emesis. The aim of this study was to compare the influence of propofol to that of enflurane on the postoperative nausea & vomiting after pediatric strabismus surgery.
METHODS
Forty children scheduled for strabismus surgery were randomly assigned into two groups according to the induction agent and main anesthetics. Propofol group (n=20) received propofol, Enflurane gruop (n=20) thiopental as an induction agent and anesthesia were maintained either propofol- O2-air or enflurane-O2-air. The incidence of postoperative nausea & vomiting was assessed at awakening period, in the recovery room and at the 1st, 2nd day after operation. Operation time, awakening time and the incidence of oculocardiac reflex were evaluated.
RESULTS
The operation time was not different between two groups, and the awakening time was shorter in Propofol group than in Enflurane group. Although oculocardiac reflexes were more frequently seen in Propofol group, no cases of postoperative nausea & vomiting were seen in Propofol group. The incidence of postoperative nausea & vomiting was not significantly different between two groups except at the 1st day after operation. At that time, the incidence of nausea was greater in Enflurane group than in Propofol group.
CONCLUSION
These findings indicated that propofol resulted in a more rapid recovery and less postoperative nausea & vomiting than enflurane, but more oculocardiac reflexes were seen in propofol.

Keyword

Anesthetics, volatile: enflurane; Anesthetics, intravenous: propofol; Complication: nausea; vomiting; oculocardiac reflex; Surgery, pediatic: strabismus

MeSH Terms

Anesthesia
Anesthetics
Child
Enflurane*
Humans
Incidence
Nausea
Postoperative Nausea and Vomiting*
Propofol*
Recovery Room
Reflex, Oculocardiac
Strabismus*
Thiopental
Vomiting*
Anesthetics
Enflurane
Propofol
Thiopental