Korean J Anesthesiol.  1992 Dec;25(6):1195-1199. 10.4097/kjae.1992.25.6.1195.

The Preventive Effect of Propofol on Postoperative Nausea and Vomiting after Strabismus Surgery in Pediatric Patients

• Lee HK
• Kim WO
• Kil HK
• Kim JR

• KMID: 1934113
• DOI: http://doi.org/10.4097/kjae.1992.25.6.1195

Abstract

Nausea and vomiting are common problems after strabismus surgery in pediatric patients. We compared the effect of propofol with N2O with the effect of a conventional regimen consisting of halothane - N2O on the occurrence of oculocardiac reflex(OCR), recovery characteristics and the incidence of postoperative emesis after strabismus surgery in 46 ASA physical status I children. After intravenous injection of atropine(0.02 mg/kg), patients were randomly assigned to one of two groups. Group l(conrol) received thiopental, vecuronium, halothane and N2O; Group 2(study), propofol 2 mg/kg and vecuronium bolus followed by infusion of propofol 160 mg/kg/min. Patients in group 2 had more episodes of OCR response than group 1, but had shorter time to recovery from anesthesia(p<0;05). But there was no significant difference in the incidence of postoperative nausea and vomiting between two groups. We conclude that the sufficient doses of propofol only regimen and atropine preadministration(0.02 mg/kg) will be necessary in the strabismus surgery of children for the purposes of the prevention of intraoperative OCR, rapid recovery from anesthesia and reduction of postoperative emesis.

Keyword

Nausea; Vomiting; Oculocardiac reflex; Propofol

MeSH Terms

Anesthesia
Atropine
Child
Halothane
Humans
Incidence
Injections, Intravenous
Nausea
Postoperative Nausea and Vomiting*
Propofol*
Reflex, Oculocardiac
Strabismus*
Thiopental
Vecuronium Bromide
Vomiting
Atropine
Halothane
Propofol
Thiopental
Vecuronium Bromide