- External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old
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Ji SH, Lee JH, Cho JY, Kim HS, Jang YE, Kim EH, Kim JT, Kim HS
- KMID: 2471791
- J Korean Med Sci.
- 2020 Mar;35(11):e70.
- doi: 10.3346/jkms.2020.35.e70
BACKGROUND: Previously, a linked pharmacokinetic-pharmacodynamic model (the Kim model) of propofol with concurrent infusion of remifentanil was developed for children aged 2–12 years. There are few options for pharmacokinetic-pharmacodynamic model... -
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- Medium- and long-chain triglyceride propofol reduces the activity of acetyl-coenzyme A carboxylase in hepatic lipid metabolism in HepG2 and Huh7 cells
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Wang LY, Wu J, Gao YF, Lin DM, Ma J
- KMID: 2466566
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):19-26.
- doi: 10.4196/kjpp.2020.24.1.19
Medium- and long-chain triglyceride (MCT/LCT) propofol is widely used as an intravenous anesthetic, especially in the intensive care unit. The present study aimed to assess whether MCT/LCT propofol is safe... -
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- Increased Effect-Site Concentration of Propofol Reduces ECâ‚…â‚€ of Remifentanil for Successful Intubation Using the Shikani Optical Stylet without Neuromuscular Blockade
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Cho SY, Lee CW, Park HJ, Park SH, Jeon WJ
- KMID: 2470409
- Soonchunhyang Med Sci.
- 2019 Dec;25(2):104-109.
- doi: 10.0000/sms.2019.25.2.104
OBJECTIVE: For short-duration surgery, propofol and remifentanil are the drugs of choice for intubation without neuromuscular blockade. The Shikani Optical Stylet (SOS) is a novel semi-rigid type fiberoptic laryngoscope. In... -
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- Effects of propofol, desflurane, and sevoflurane on respiratory functions following endoscopic endonasal transsphenoidal pituitary surgery: a prospective randomized study
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Oguz A, Akcil EF, Tunali Y, Vehid H, Dilmen OK
- KMID: 2465728
- Korean J Anesthesiol.
- 2019 Dec;72(6):583-591.
- doi: 10.4097/kja.19336
BACKGROUND: General anesthesia with intravenous or inhalation anesthetics reduces respiratory functions. We investigated the effects of propofol, desflurane, and sevoflurane on postoperative respiratory function tests. METHODS: This single-center randomized controlled study... -
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- Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation
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Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L
- KMID: 2463799
- Yonsei Med J.
- 2019 Dec;60(12):1195-1202.
- doi: 10.3349/ymj.2019.60.12.1195
PURPOSE: The aim of this study was to investigate whether propofol could attenuate hypoxia/reoxygenation-induced apoptosis and autophagy in human renal proximal tubular cells (HK-2) by inhibiting JNK activation. MATERIALS AND METHODS:... -
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- Can Propofol Lead to an Increase in Seizure Threshold Over the Course of Electroconvulsive Therapy?
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Aytuluk HG, Simsek T, Yilmaz M, Turan AZ, Saracoglu
- KMID: 2464719
- Clin Psychopharmacol Neurosci.
- 2019 Nov;17(4):523-530.
- doi: 10.9758/cpn.2019.17.4.523
OBJECTIVE: To evaluate the effects of 2 different dose regimens of propofol (low dose: < 1 mg/kg, high dose: ≥ 1 mg/kg) on the duration of the seizures, the required... -
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- Effects site concentrations of propofol using target-controlled infusion in dental treatment under deep sedation among different intellectual disability types
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Salinas Salmeron KS, Kim HJ, Seo KS
- KMID: 2456013
- J Dent Anesth Pain Med.
- 2019 Aug;19(4):217-226.
- doi: 10.17245/jdapm.2019.19.4.217
BACKGROUND: We aimed to assess the dose needed to achieve the propofol effect-site concentration using target-controlled infusion in intellectually disabled patients and to detail the most effective method for achieving... -
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- The Author's Response: Evaluation of Propofol in Comparison with Other General Anesthetics for Surgery in Children Younger than 3 Years: a Systematic Review and Meta-Analysis
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Hong H, Hahn S, Choi Y, Jang MJ, Kim S, Lee JH, Kim HS
- KMID: 2452633
- J Korean Med Sci.
- 2019 Jul;34(28):e192.
- doi: 10.3346/jkms.2019.34.e192
No abstract available. -
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- Letter to the Editor: Is Propofol Good Choice for Procedural Sedation? Evaluation of Propofol in Comparison with Other General Anesthetics for Surgery in Children Younger than 3 Years
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Kim SC
- KMID: 2452632
- J Korean Med Sci.
- 2019 Jul;34(28):e191.
- doi: 10.3346/jkms.2019.34.e191
No abstract available. -
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- Three minutes propofol after sevoflurane anesthesia to prevent emergence agitation following inguinal hernia repair in children: a randomized controlled trial
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Abbas MS, El-Hakeem , Kamel HE
- KMID: 2454884
- Korean J Anesthesiol.
- 2019 Jun;72(3):253-259.
- doi: 10.4097/kja.d.18.00345
BACKGROUND: Emergence agitation (EA) is a common problem after sevoflurane anesthesia among children. There have been mixed results with control of EA using propofol 1 mg/kg bolus following sevoflurane anesthesia.... -
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- Propofol Suppresses LPS-Induced Inflammation in Amnion Cells via Inhibition of NF-κB Activation
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Yoon JY, Kim DW, Ahn JH, Choi EJ, Kim YH, Jeun M, Kim EJ
- KMID: 2449240
- Tissue Eng Regen Med.
- 2019 Jun;16(3):301-309.
- doi: 10.1007/s13770-019-00194-y
BACKGROUND: Preterm labor is a leading risk factor for neonatal death and long-term impairment and linked closely with inflammation. Non-obstetric surgery is occasionally needed during pregnancy and the anesthetic drugs... -
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- Propofol with and without Midazolam for Diagnostic Upper Gastrointestinal Endoscopies in Children
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Akbulut UE, Kartal S, Dogan U, Akcali GE, Kalayci S, Kirci H
- KMID: 2444847
- Pediatr Gastroenterol Hepatol Nutr.
- 2019 May;22(3):217-224.
- doi: 10.5223/pghn.2019.22.3.217
PURPOSE: Various publications on the use of sedation and anesthesia for diagnostic procedures in children have demonstrated that no ideal agent is available. Although propofol has been widely used for... -
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- Dexmedetomidine and propofol sedation requirements in an autistic rat model
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Elmorsy SA, Soliman GF, Rashed LA, Elgendy H
- KMID: 2447512
- Korean J Anesthesiol.
- 2019 Apr;72(2):169-177.
- doi: 10.4097/kja.d.18.00005
BACKGROUND: Autism is a challenging neurodevelopmental disorder. Previous clinical observations have suggested altered sedation requirements for children with autism. Our study aimed to test this observation experimentally in an animal... -
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- Pharmacodynamic Analysis of the Influence of Propofol on Left Ventricular Long-Axis Systolic Performance in Cardiac Surgical Patients
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Bang JY, Kim S, Choi BM, Kim TY
- KMID: 2443596
- J Korean Med Sci.
- 2019 Apr;34(16):e132.
- doi: 10.3346/jkms.2019.34.e132
BACKGROUND: Propofol induced a decline in the left ventricular (LV) systolic performance in non-cardiac surgery. We tested the hypothesis that propofol decreased the LV contractile function by dose dependent manner... -
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- Evaluation of Propofol in Comparison with Other General Anesthetics for Surgery in Children Younger than 3 Years: a Systematic Review and Meta-Analysis
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Hong H, Hahn S, Choi Y, Jang MJ, Kim S, Lee JH, Kim HS
- KMID: 2443209
- J Korean Med Sci.
- 2019 Apr;34(15):e124.
- doi: 10.3346/jkms.2019.34.e124
BACKGROUND: Despite well-known advantages, propofol remains off-label in many countries for general anesthesia in children under 3 years of age due to insufficient evidence regarding its use in this population.... -
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- Effects of preanesthetic single administration of dexmedetomidine on the remifentanil and propofol requirement during laparoscopic cholecystectomy
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Park H, Kim HS, Kim JW, Lee GG, Park DH, Jeong CY, Park SG, Ryu KH
- KMID: 2434195
- Anesth Pain Med.
- 2019 Jan;14(1):29-34.
- doi: 10.17085/apm.2019.14.1.29
BACKGROUND: Dexmedetomidine, an α2-adrenergic agonist, can be used for sedation and as an adjuvant to anesthetics. This study aimed to evaluate the effects of preanesthetic administration of dexmedetomidine on the... -
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- Propofol promotes osteoclastic bone resorption by increasing DC-STAMP expression
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Kim EJ, Kim HJ, Baik SW, Kim KH, Ryu SJ, Kim CH, Shin SW
- KMID: 2430212
- J Dent Anesth Pain Med.
- 2018 Dec;18(6):349-359.
- doi: 10.17245/jdapm.2018.18.6.349
BACKGROUND: Propofol is an intravenous anesthetic which has antioxidant effects due to its similarity in molecular structure to α-tocopherol. It has been reported that α-tocopherol increases osteoclast fusion and bone... -
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- Evaluation of efficacy of Valsalva maneuver for attenuating propofol injection pain: a prospective, randomized, single blind, placebo controlled study
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Kumar S, Khuba S, Agarwal A, Gautam S, Yadav M, Dixit A
- KMID: 2428077
- Korean J Anesthesiol.
- 2018 Dec;71(6):453-458.
- doi: 10.4097/kja.d.18.00017
BACKGROUND: Pain on injection is a limitation with propofol use. The effect of the Valsalva maneuver on pain during propofol injection has not been studied. This maneuver reduces pain through... -
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- Ketamine with Propofol for Endoscopic Procedures
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Bhalotra A
- KMID: 2418537
- Korean J Anesthesiol.
- 2018 Aug;71(4):334-335.
- doi: 10.4097/kja.d.18.00037
No abstract available. -
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- Comparison of sevoflurane and propofol anesthesia on the incidence of hyperglycemia in patients with type 2 diabetes undergoing lung surgery
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Kim H, Han J, Jung SM, Park SJ, Kwon NK
- KMID: 2415734
- Yeungnam Univ J Med.
- 2018 Jun;35(1):54-62.
- doi: 10.12701/yujm.2018.35.1.54
BACKGROUND: The type and regimen of anesthesia may affect perioperative hyperglycemia following major surgical stress. This study compared the effects of sevoflurane and propofol on the incidence of hyperglycemia and... -
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