Korean J Anesthesiol.  2007 Sep;53(3):S58-S60. 10.4097/kjae.2007.53.3.S58.

Experience of Suspected Propofol Infusion Syndrome in a Status Epilepticus Patient: A case report

• Jung YH
• Kang DU
• Lee SS
• Lim YH
• Yoo BH
• Yon JH

• KMID: 2039651
• DOI: http://doi.org/10.4097/kjae.2007.53.3.S58

Abstract

Propofol is used for the treatment of refractory status epilepticus. When given as a long-term infusion, in combination with catecholamines and/or steroids, propofol rarely causes the fatal complication, known a propofol infusion syndrome. Herein, the case of a previously healthy 8-years-old boy with status epilepticus is reported. He was treated with propofol, in doses ranging from 8.6 to 10.9 mg/kg/h, for 43 hours. The propofol resulted in multiple organ failure, with rhabdomyolysis, which caused the death of the patient. This case fulfills all the criteria of propofol infusion syndrome.

Keyword

multiple organ failure; propofol; propofol infusion syndrome; status epilepticus

MeSH Terms

Catecholamines
Humans
Male
Multiple Organ Failure
Propofol*
Rhabdomyolysis
Status Epilepticus*
Steroids
Catecholamines
Propofol
Steroids