Korean J Thorac Cardiovasc Surg.  2006 Apr;39(4):304-309.

Interstitial Pneumonia and Lung Cancer Surgery

• Park JK
• Sa YJ
• Wang YP

Abstract

BACKGROUND: Interstitial pneumonia is associated with an increased risk of lung cancer but the outcome of surgical resection in this setting is unknown. The purpose of this study was to determine the relationship between pre-operative interstitial pneumonia (IP) and post-operative respiratory failure. MATERIAL AND METHOD: A retrospective review of 672 patients with lung cancer who underwent curative pulmonary resection at the Hospital of Catholic University Medical College between 1997 and 2005 was undertaken. The patients were divided into two groups according to preexisting interstitial pneumonia and not by the pre-operative chest HRCT or findings of pathologic papers. The pre-operative data and cancer-related findings were analyzed between the IP group and non-IP group, and between the respiratory failure group and non-failure group in IP patients. RESULT: Twenty-eight patients (4.2%) of the developed post-operative respiratory failure and this proved to be fatal in 21 of these patients. We could find preoperative interstitial pathology in 53 patients (7.9%) among the 672 patients. The incidences of respiratory failure were 11.3% (6/53 cases) and 3.6% (22/619 cases) in IP group and non-IP group respectively.
CONCLUSION
Interstitial pneumonia was considered one of the risk factors for developing postoperative acute respiratory failure in patients with lung cancer.

Keyword

Lung neoplasms; Pneumonia; Surgery; Acute respiratory distress syndrome

MeSH Terms

Humans
Incidence
Lung Diseases, Interstitial*
Lung Neoplasms*
Lung*
Pathology
Pneumonia
Respiratory Distress Syndrome, Adult
Respiratory Insufficiency
Retrospective Studies
Risk Factors
Thorax