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Recent Advances in Molecular Basis of Lung Aging and Its Associated Diseases

Kang MJ

Aging is often viewed as a progressive decline in fitness due to cumulative deleterious alterations of biological functions in the living system. Recently, our understanding of the molecular mechanisms underlying...
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Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway

Masraksa W, Tanasawet , Hutamekalin P, Wongtawatchai T, Sukketsiri W

BACKGROUND/OBJECTIVES: Non-small cell lung cancer is mostly recognized among other types of lung cancer with a poor prognosis by cause of chemotherapeutic resistance and increased metastasis. Luteolin has been found...
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Psoriasiform Dermatitis Related with T-Cell Immunoreceptor with Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Motif Domains Inhibitor in a Patient with Non-Small-Cell Lung Cancer

Choi Y, Jang D, Byun HJ, Oh SJ, Kim CR, Park JH, Lee JH, Lee DY

No abstract available.
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The MicroRNA hsa-let-7g Promotes Proliferation and Inhibits Apoptosis in Lung Cancer by Targeting HOXB1

Cui F, Zhou Q, Xiao K, Ma S

PURPOSE: The goal of this study was to explore the effects of hsa-let-7g on cell proliferation and apoptosis, and elucidate its role in lung cancer development. MATERIALS AND METHODS: The expression...
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Lung Pathology in Septic Shock with Leukopenia

Huh GY

Sepsis-related deaths are occasionally encountered in forensic practice. However, forensic pathologists are reluctant to use the terminology “sepsis” or “septic shock” as a cause of death because of the lack...
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Radiomics in Lung Cancer from Basic to Advanced: Current Status and Future Directions

Lee G, Park H, Bak SH, Lee HY

Ideally, radiomics features and radiomics signatures can be used as imaging biomarkers for diagnosis, staging, prognosis, and prediction of tumor response. Thus, the number of published radiomics studies is increasing...
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Applying Extended Theory of Planned Behavior for Lung Cancer Patients Undergone Pulmonary Resection: Effects on Self-Efficacy for Exercise, Physical Activities, Physical Function, and Quality of Life

Lim Y, Lee H, Kim DH, Kim YD

PURPOSE: This study aims to examine the effects of nursing interventions based on the Extended Theory of Planned Behavior (ETPB) regarding self-efficacy for exercise (SEE), physical activity (PA), physical function...
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Immunotherapy for Non-small Cell Lung Cancer: Current Landscape and Future Perspectives

Lim SM, Hong MH, Kim HR

Immune checkpoint inhibitors (ICIs) have shown remarkable benefit in the treatment of patients with non-small-cell lung cancer (NSCLC) and have emerged as an effective treatment option even in the first-line...
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NOTCH1 Pathway is Involved in Polyhexamethylene Guanidine-Induced Humidifier Disinfectant Lung Injuries

Lee E, Kang MJ, Kim JH, Lee SH, Lee SY, Cho HJ, Yoon J, Jung S, Park Y, Oh DK, Hong SB, Hong SJ

An outbreak of fatal humidifier disinfectant lung injuries (HDLI) occurred in Korea. Human studies on mechanisms underlying HDLI have yet to be conducted. This study aimed to investigate methylation changes...
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Cystic fibrosis lung disease: Current perspectives

Jung JA

Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). These mutations alter the synthesis, processing, function, or...
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Performances of CYFRA 21-1, Carcinoembryonic Antigen and Their Combination for Lung Cancer Diagnosis

Kim JJ, Ahn HJ, Park Y

BACKGROUND: The aim of this study was to compare the efficiency of cytokeratin 19 fragment (CYFRA 21-1) and carcinoembryonic antigen (CEA) for the diagnosis of lung cancer and to establish...
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Circulating Tumor Cell Number Is Associated with Primary Tumor Volume in Patients with Lung Adenocarcinoma

Kang BJ, Ra SW, Lee K, Lim S, Son SH, Ahn JJ, Kim BC

BACKGROUND: Circulating tumor cells (CTCs) are frequently detected in patients with advanced-stage malignant tumors and could act as a predictor of poor prognosis. However, there is a paucity of data...
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Correlation of PD-L1 Expression Tested by 22C3 and SP263 in Non-Small Cell Lung Cancer and Its Prognostic Effect on EGFR Mutation–Positive Lung Adenocarcinoma

Kim T, Cha YJ, Chang YS

BACKGROUND: Programmed death-ligand 1 (PD-L1) expression is tested by immunohistochemistry (IHC)—22C3, SP263, and SP142. The aim of this study is to evaluate the correlation among the three methods of PD-L1...
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Current Status of Immunotherapy for Lung Cancer and Future Perspectives

Kim HC, Choi CM

Lung cancer remains the most common cause of cancer-related deaths worldwide. Although there are many possible treatments, including targeted therapies such as epidermal growth factor receptor tyrosine kinase inhibitors and...
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Problems with diagnostic criteria for humidifier disinfectant lung injury (HDLI): two cases of radiologically improved HDLI

Nam MW, Park SY, Suh BS, Ham SY, Son KH, Kim H, Kim HC

BACKGROUND: In Korea, to investigate the casual relationship between humidifier disinfectant and lung disease, four rounds of investigation and judgment were conducted. During this investigation, two adults who performed lung...
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Effects of Instability Tools on Muscles Activities in Lunge Exercise in Healthy Adult Males

Kim K, Lee J, Lee J, Lee J

PURPOSE: This study was to investigate the effect of instability on the activation of lower limb muscles during lunge exercise. METHODS: The study subjects were healthy twenties and were selected to...
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Persistent Horner Syndrome after Stellate Ganglion Block in Lung Cancer Patient

Jung HS

A 46-year-old male patient was admitted due to sudden hyperhidrosis of face. His past history was chemotherapy with lung cancer, bone metastasis, and brain metastasis. Horner syndrome, such as ptosis,...
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A Case of Lung Abscess Caused by Pulmonary Actinomycosis

Hwang SW

Actinomycosis is a slowly progressive and indolent infectious disease characterized by acute suppurative inflammation, necrosis, and fibrosis. It usually occurs in cervicofacial, abdominopelvic, and pulmonary areas. Pulmonary actinomycosis accounts for...
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A Man Presenting with Sudden Weakness and Pain of the Right Hand, by Non-Small Cell Lung Cancer with Brain Metastases

Sung WJ, Hong BY, Kim JS, Yoo JW, Lim SH

Unexplained pain and weakness, i.e., without obvious predisposing factors, are often encountered by physiatrists and efforts should be made to determine the cause. A 63-year-old male presented with radiating pain...
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Chronic Traumatic Glass Foreign Body Removal from the Lung through a Direct Parenchymal Incision

Yoon SY, Kim SW, Lee JS, Lee JY, Ye JB, Kim SH, Sul YH

Traumatic intrapulmonary glass foreign bodies that are missed on an initial examination can migrate and lead to severe complications. Here, we present a rare case of a traumatic intrapulmonary glass...
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