J Asthma Allergy Clin Immunol.
2000 Jun;20(3):467-480.
Multi-center study for the utilization of quality of life questionnaire for adult Korean asthmatics (QLQAKA)
- Affiliations
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- 1Committee for development of Quality of Life Questionnaire for Adult Korean Asthmatics, Korean
Society of Allergology, Department of Preventive Medicine, Ajou University School of Medicine*,
Department of Biostatistics, Yonsei University College of Medic
Abstract
- BACKGROUND AND OBJECTIVE
Assessment of quality of life (QOL) of patients with chronic illness requires reasonable tools which reflect the patients' cultural and behavioral properties. We developed the quality of life questionnaire for adult Korean asthmatics (QLQAKA) on the basis of the Korean life style and evaluated its reliability and validity.
METHODS
The QLQAKA consisted of four domains; symptoms (six items), daily activity (five items), emotion (three items) and reaction to environmental stimuli (three items). Patients answered each item according to a five-response scale. The reproducibility and validity of the questionnaire was estimated from the responses of 244 patients who visited the clinics in 15 institutes within a 2-week interval.
RESULTS
Items with the most frequent complaints were dyspnea (87%), difficulty in sputum discharge or throat clearing (87%), limitation in strenuous activity (84%) and coughing (82.4%). The QLQAKA reflected the changes of patients' status very well. The value of minimal important differences, such as the clinically significant minimal change in the QOL score, was 0.5. The questionnaire was also highly reproducible with the value of intraclass correlation coefficiency and intraclass standard deviation as 0.940 (p<0.001) and 0.180, respectively. The changes of mean total QLQAKA score correlated weakly with the changes of FEV1 and PEFR values.
CONCLUSION
The adult version of QLQAKA was valid and may be a reproducible tool for evaluating and monitoring Korean adult asthma patients.