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Clinical efficacy and compliance of dupilumab therapy in adolescent and adult patients with atopic dermatitis in real clinical practice: An analysis of data from a single allergy clinic in Korea

Lee Y, Kim ME, Nahm DH

Purpose: Dupilumab (a monoclonal antibody to interleukin-4 receptor alpha) is the first biological agent approved for the treatment of moderate-to-severe atopic dermatitis (AD). We evaluated the clinical efficacy and compliance...
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Causes of food allergy according to age and severity: A recent 10-year retrospective study from a single tertiary hospital

Lee E, Jeong K, Shin YS, Nahm DH, Park HS, Choi HN, Yoon J, Ye YM, Lee S

Purpose: Recent studies of food allergy (FA) at all ages are scanty in Korea. We performed this study to better understand severity-related and age-stratified causes of FA from infants to...
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Safety of Ultra-rush Schedule of Subcutaneous Allergen Immunotherapy With House Dust Mite Extract Conducted in an Outpatient Clinic in Patients With Atopic Dermatitis and Allergic Rhinitis

Lee SH, Kim ME, Shin YS, Ye YM, Park HS, Nahm DH

PURPOSE: Ultra-rush schedule of subcutaneous allergen immunotherapy (UR-SCIT) administering maximum maintenance dose of allergen extract within one day can save time and effort for allergen immunotherapy in patients with allergic...
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Factors Associated with Adherence to Allergen Specific Subcutaneous Immunotherapy

Lee JH, Lee SH, Ban GY, Ye YM, Nahm DH, Park HS, Shin YS

PURPOSE: Allergen-specific immunotherapy (AIT) is known to be the only therapeutic modality to alter the natural course of allergic diseases. However, at least 3 years of treatment is recommended for...
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Therapeutic Effect of Omalizumab in Severe Asthma: A Real-World Study in Korea

Lee JH, Lee HY, Jung CG, Ban GY, Shin YS, Ye YM, Nahm DH, Park HS

PURPOSE: Omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, has proved to be effective for the treatment of severe asthma. However, there is no direct evidence of effectiveness of omalizumab in...
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A Retrospective Study of Clinical Response Predictors in Subcutaneous Allergen Immunotherapy With House Dust Mites for Allergic Rhinitis

Lee JH, Kim SC, Choi H, Jung CG, Ban GY, Shin YS, Nahm DH, Park HS, Ye YM

PURPOSE: House dust mites (HDM) are major allergens that cause allergic rhinitis (AR). Allergen-specific subcutaneous immunotherapy (SCIT) has been shown to be clinically beneficial in many clinical trials. Such trials,...
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Linguistic adaptation of the rhinitis control assessment test in Korean

Kim MA, Ye YM, Ban GY, Shin YS, Nahm DH, Park HS

PURPOSE: Allergic rhinitis is one of the most common chronic diseases that affect in sleep, fatigue, headache, impaired cognition, and performances at work or school. Monitoring rhinitis control is important,...
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Subcutaneous Immunotherapy for Allergic Asthma in a Single Center of Korea: Efficacy, Safety, and Clinical Response Predictors

Lee JH, Kim SC, Choi H, Jung CG, Ban GY, Shin YS, Nahm DH, Park HS, Ye YM

Allergen-specific immunotherapy is the only causal treatment for allergic diseases. However, the efficacy of immunotherapy may vary around the world due to differences in climate, the nature of aero-allergens and...
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Clinical Efficacy of Subcutaneous Allergen Immunotherapy in Patients with Atopic Dermatitis

Nahm DH, Kim ME, Kwon B, Cho SM, Ahn A

PURPOSE: The clinical usefulness of subcutaneous allergen immunotherapy (SCIT) in the treatment of atopic dermatitis (AD) is still controversial. We analyzed the clinical efficacy of SCIT in patients with AD...
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Multicenter questionnaires on the current management of atopic dermatitis in Korea

Lee DH, Doh EJ, Lee JY, Park Y, Oh JW, Lee MH, Hong SJ, Lee SY, Park JS, Nahm DH, Yum HY, KAACI Work Group on Severe/Recalcitrant Atopic Dermatitis

PURPOSE: The effective management of atopic dermatitis (AD) adjusted to individual clinical courses and demands can be challenging to both patients and physicians. Understanding of actual situations, experienced and perceived...
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Autologous Immunoglobulin Therapy in Patients With Severe Recalcitrant Atopic Dermatitis: Long-Term Changes of Clinical Severity and Laboratory Parameters

Nahm DH, Ahn A, Kim ME, Cho SM, Park MJ

This report evaluated long-term changes in clinical severity and laboratory parameters in 3 adult patients with severe recalcitrant atopic dermatitis (AD) who were treated with intramuscular injections of 50 mg...
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Associations of Atopic Dermatitis With Obesity and Unmarried Status in Young Adults: Evidence for Atopic Dermatitis as a Life-Style Disorder With High Social Impact

Nahm DH

No abstract available.
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Favorable outcome of omalizumab treatment in a patient with idiopathic anaphylaxis

Ban GY, Yang EM, Kim JH, Shin YS, Ye YM, Nahm DH, Park HS

Anaphylaxis is a severe and life-threatening systemic reaction. Despite the extensive evaluation to determine the cause, 30%-60% of cases of anaphylaxis in adults remain idiopathic. Recently, omalizumab treatment has been...
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Personalized Immunomodulatory Therapy for Atopic Dermatitis: An Allergist's View

Nahm DH

The current standard medical therapy for atopic dermatitis (AD) mainly focuses on symptomatic relief by controlling skin inflammation with topical corticosteroids and/or topical calcineurin inhibitors. However, the clinical efficacy of...
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Immunologic Evaluation of Patients with Cefotetan-Induced Anaphylaxis

Nam YH, Hwang EK, Ban GY, Jin HJ, Yoo HS, Shin YS, Ye YM, Nahm DH, Park HS, Lee SK

Cefotetan is a commonly prescribed second-generation cephalosporin that acts against a wide range of bacteria. However, cefotetan-induced hypersensitivity has rarely been reported. We report 2 cases of cefotetan-induced anaphylaxis with...
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Present and future of allergen immunotherapy for allergic diseases

Nahm DH

Current pharmacological therapies for allergic diseases can improve clinical symptoms but cannot change their long-term clinical course. There is an unmet need for a curative treatment for allergic diseases. Allergen...
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Clinical features of elderly chronic urticaria

Ban GY, Kim MY, Yoo HS, Nahm DH, Ye YM, Shin YS, Park HS

BACKGROUND/AIMS: Chronic urticaria (CU) is defined as itchy wheals lasting 6 weeks or more. As the aged population increases worldwide, it is essential to identify the specific features of this...
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Clinical Characteristics of Angioedema With Eosinophilia

Cho HJ, Yoo HS, Kim MA, Shin YS, Ye YM, Nahm DH, Kim JH, Choi JH, Park SY, Park HS

Angioedema with eosinophilia (AE) is a very rare allergy disease, case reports of which have been published sporadically since 1984. Here, we retrospectively analyzed the clinical features of 10 AE...
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The Prevalence of Serum Specific IgE to Superantigens in Asthma and Allergic Rhinitis Patients

Liu JN, Shin YS, Yoo HS, Nam YH, Jin HJ, Ye YM, Nahm DH, Park HS

Staphylococcus aureus is the most common bacterium present in upper respiratory tract, and the toxins it produced are involved in allergic inflammation pathogenesis. In this study, we investigated the clinical...
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A Case of Codeine Induced Anaphylaxis via Oral Route

Yoo HS, Yang EM, Kim MA, Hwang SH, Shin YS, Ye YM, Nahm DH, Park HS

Codeine is widely prescribed in clinical settings for the relief of pain and non-productive coughs. Common adverse drug reactions to codeine include constipation, euphoria, nausea, and drowsiness. However, there have...
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