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Long-term Surgical Outcomes in Oligometastatic Non-small Cell Lung Cancer: A Single-Center Study

Yoo S, Cho WC, Lee GD, Choi S, Kim HR, Kim YH, Kim DK, Park SI, Yun JK

Background: We reviewed the clinical outcomes of patients with oligometastatic (OM) non-small cell lung cancer (NSCLC) who received multimodal therapy including lung surgery. Methods: We retrospectively analyzed 117 patients with OM...
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Early Outcomes of COVID-19 Lung Transplantation Recipients in Korea: A Single-Center Study

Kim SA, Yun JK, Lee GD, Kim DK, Choi S

Background: Coronavirus disease 2019 (COVID-19) has been found to cause life-threatening respiratory failure, which can progress to irreversible lung damage. Lung transplantation can be a life-saving treatment in patients with...
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Effect of male age on reproductive function: A comparison of young and middle-aged men

Lee TH, Kim DS, Kim DK, Shin DH, Oh M, Lee WH, Song SH

Purpose: There have been concerns regarding potential effects of older paternal age on male reproductive function. However, currently available data on this topic are insufficient and controversy exists. We analyzed...
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Rapid FEV 1 /FVC Decline Is Related With Incidence of Obstructive Lung Disease and Mortality in General Population

Choi KY, Lee HJ, Lee JK, Park TY, Heo EY, Kim DK, Lee HW

Background: Forced expiratory volume in 1 second (FEV1 )/forced vital capacity (FVC) naturally decreases with age; however, an excessive decline may be related with increased morbidity and mortality. This study...
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Thrombin Induced Apoptosis through Calcium-Mediated Activation of Cytosolic Phospholipase A2 in Intestinal Myofibroblasts

Park MJ, Won JH, Kim DK

Thrombin is a serine protease that participates in a variety of biological signaling through protease-activated receptors. Intestinal myofibroblasts play central roles in maintaining intestinal homeostasis. In this study, we found...
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Impact of Evolutionary Changes in Nonalcoholic Fatty Liver Disease on Lung Function Decline

Lee HW, Chung GE, Koo BK, Sim H, Choi M, Lee DH, Choi SH, Kwak SH, Kim DK, Kim W, obotITEoN(c

Background/Aims: A relationship between fatty liver and lung function impairment has been identified, and both are independently associated with metabolic dysfunction. However, the temporal relationship between changes in fatty liver...
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Azoospermic Men with a History of Cryptorchidism Treated by Orchiopexy Have Favorable Outcomes after Testicular Sperm Extraction: A Systematic Review and Meta-Analysis

Kim SW, Lee J, Lee TH, Kim DS, Song SH, Kim DK

Purpose: This systematic review and meta-analysis investigated the sperm retrieval rate (SRR) and pregnancy rate after testicular sperm extraction in men with azoospermia and those with a history of cryptorchidism...
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Effects of cimifugin on cell growth inhibition and cell apoptosis induction in fadu human pharyngeal squamous cell carcinoma

Park JH, Kim DK

Cimifugin is an important component of chromones in the dry roots of Saposhnikovia divaricata and is used in treating inflammatory diseases. However, the effect of cimifugin on cancer is unclear....
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Effect of Cannabidiol Oil on Weight Loss in Diet-Induced Obese Mice: Validation Study

Han SS, Lim SW, Woo Sy, Lee SJ, Kim DK

Objectives This study aimed at investigating the pharmacological and physiological effects of cannabidiol (CBD) oil on weight loss in diet-induced obese (DIO) mice. Methods A DIO mice model was constructed with...
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Phascolarctobacterium-producing propionate and acute rejection of kidney transplant recipients

Cho H, Park JI, Kim JE, Lee 4 JW, Kim YC, Lee JP, Kim DK, Kim YS, Lee H

Background: Acute rejection (AR) is associated with worse long-term allograft survival. Therefore, identifying and regulating the potential risk factors of AR is very important. Growing evidence has shown that gut...
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Bridging to lung transplantation in idiopathic pulmonary fibrosis

Kim G, Oh DK, Shim TS, Kim DK, Choi S, Lee GD, Kim W, Park SI, Hong SB

Background: Among interstitial lung diseases (ILD), idiopathic pulmonary fibrosis (IPF) and connective tissue diseases (CTD) have different characteristics and prognosis; IPF is associated with older age and poor prognosis. Donor...
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Arctigenin induces caspase-dependent apoptosis in FaDu human pharyngeal carcinoma cells

Kang KR, Kim JS, Lim H, Seo JY, Park JH, Chun HS, Yu SK, Kim HJ, Kim CS, Kim DK

The present study was carried out to investigate the effect of Arctigenin on cell growth and the mechanism of cell death elicited by Arctigenin were examined in FaDu human pharyngeal...
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A Novel Therapeutic Effect of a New Variant of CTLA4-Ig with Four Antennas That Are Terminally Capped with Sialic Acid in the CTLA4 Region

Piao Y, Yun SY, Kim HS, Park BK, Ha HC, Fu Z, Jang JM, Back MJ, Shin IC, Won JH, Kim DK

Rheumatoid arthritis (RA) is a multifactorial immune-mediated disease, the pathogenesis of which involves different cell types. T-cell activation plays an important role in RA. Therefore, inhibiting T-cell activation is one...
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Relationship between Androgen Deprivation Therapy and Normal-Tension Glaucoma in Patients with Prostate Cancer: A Nationwide Cohort Study

Ha JS, Lee HS, Park JY, Jeon J, Kim DK, Kim M, Hwang HS, Kim TH, Ahn HK, Cho KS

Purpose: This study assessed the relationship between newly developed normal-tension glaucoma (NTG) and androgen deprivation therapy (ADT) in patients with prostate cancer. Materials and Methods: A retrospective population-based cohort study was...
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Natural Course of Swallowing Recovery and Associated Factors in Post-Ischemic Stroke Dysphagia

Suh JW, Lim HS, Kim DK, Lee HS, Lee YT, Park YS, Park CH, Yoon KJ

Objective: To identify factors associated with swallowing recovery in patients with dysphagia after ischemic stroke. Methods: Patients admitted to Kangbuk Samsung Hospital from 2011 to 2019 for first acute ischemic stroke...
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Ultrasound-guided erector spinae plane block for pain management after gastrectomy: a randomized, single-blinded, controlled trial

Jeong H, Choi JW, Sim WS, Kim DK, Bang YJ, Park S, Yeo H, Kim H

Background: Open gastrectomy causes severe postoperative pain. Therefore, we investigated the opioid-sparing effect of the ultrasound-guided bilateral erector spinae plane block (ESPB) after open gastrectomy. Methods: Adult patients undergoing open gastrectomy...
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Androgen Deprivation Therapy in Patients with Prostate Cancer is Associated with the Risk of Subsequent Alzheimer’s Disease but Not with Vascular Dementia

Kim JW, Kim DK, Lee HS, Park JY, Ahn HK, Ha JS, Lee D, Cho KS

Purpose: We aimed to investigate the association between androgen deprivation therapy (ADT) and the risk of dementia according to subtypes of dementia in men with prostate cancer. Materials and Methods: We...
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Melioidosis from Thailand and Risk Classification and Precautionary Measures for Laboratory Staff who were Exposed

Kim MH, Kim DK, Kim JH, Ahn JY, Jeong SJ, Ku NS, Yeom JS, Choi JY

Melioidosis is an infectious disease caused by Burkholderia pseudomallei, a Gram-negative bacillus, with a fatality rate of 14-49%. They are mainly exposed to contaminated soil or water through wounds, mucosa,...
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Are Outcomes Comparable for Repair of AO/OTA Type 13C1 and Type 13C2 Distal Humeral Fractures Using the Paratricipital Approach?

Lee S, Baek E, Kim M, Kim J, Lee H, Kim DK, Jang Y, Han SH

Background: Studies have reported favorable outcomes using the paratricipital approach for fixation of distal humeral intra-articular fractures. However, literature evaluating the clinical results of the approach remains limited. The objective...
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Improvement of chewing and swallowing risks in community-dwelling older adults using texture-modified food

Park S, Kim Dk, Park H, Yoon D, Byambaa S

BACKGROUND/OBJECTIVES: Understanding the mechanism of chewing and swallowing food is important when creating a proper diet for older adults. This study investigated whether texture-modified model foods can reduce the difference...
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