Korean J Pediatr Infect Dis.
2010 Jun;17(1):49-55.
Identification of Viral Pathogens for Lower Respiratory Tract Infection in Children at Seoul During Autumn and Winter Seasons of the Year of 2008-2009
- Affiliations
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- 1Department of Pediatrics, Yonsei University College of Medicine, Severance Children's Hospital, Korea. dskim6634@yuhs.ac
- 2Department of Pediatrics, Kangnam Severance Hospital, Korea.
- 3Department of Pediatrics, Ewha Womans University College of Medicine, Korea.
- 4Division of Influenza, Korea Centers for Disease Control and Prevention, Korea.
- 5Division of Respiratory Viruses, Korea Centers for Disease Control and Prevention, Korea.
Abstract
- PURPOSE
The Purposes of this study are to identify the circulating etiologic viruses of acute lower respiratory tract infection in children and to understand the relation with clinical diagnosis.
METHODS
We obtained a total of 418 nasopharyngeal aspirates from children admitted for their acute lower respiratory tract infections at three tertiary hospitals in Seoul from September 2008 to March 2009. We performed multiplex RT-PCR to identify 14 etiologic viruses and analyzed their emerging patterns and clinical features.
RESULTS
Average age of patients was 16.4 months old and the ratio of male to female was 1.36. Viruses were detected in 56.2% of a total of 418 samples. Respiratory syncytial virus (35%) was the most frequently detected and followed by human rhinovirus (22%), human bocavirus, adenovirus, human metapneumovirus, parainfluenza virus, influenza virus and human coronavirus. Co-infection reached 21.9% of positive patients.
CONCLUSION
When we manage the patients with acute lower respiratory infectious diseases, we should remind the role of various viral pathogens, which might be circulating by seasons and by local areas.
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