- Adenovirus Expressing Human Interferon Inhibits Replication of Foot and Mouth Disease Virus and Reduces Fatal Rate in Mice
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Chu JQ, Kim SM, Lee KN, Oem JK, Ko YJ, Lee HS, Kim YJ, Park JY, Kim KJ, Parida S, Oh Y, Paton DJ, Joo YS, Kim B, Park JH
- KMID: 1434751
- J Bacteriol Virol.
- 2012 Sep;42(3):224-231.
- doi: 10.4167/jbv.2012.42.3.224
Interferon is an important cytokine that plays a critical role in the initial host defense against viral infection. Recombinant human adenoviruses expressing human interferon-alpha (Ad-HIFNalpha) or pig interferon-beta fused with... -
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- Molecular Epidemiology of Viral Conjunctivitis in the Southern Region of South Korea, 2012–2016
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Park DW, Kim MJ, Kim KG, Cho SJ, Park HJ, Shin JH, Ha YD, Seo MH, Kim JH, Lee Y, Park MD, Yoon HM, Kim ES, Hong YJ, Kee H, Chung JK
- KMID: 2414856
- J Bacteriol Virol.
- 2018 Jun;48(2):59-66.
- doi: 10.4167/jbv.2018.48.2.59
Epidemic keratoconjunctivitis (EKC) and acute hemorrhagic conjunctivitis (AHC) are common diseases caused by human adenoviruses (HAdV) and enteroviruses, respectively, in South Korea. However, there are limited studies on the molecular... -
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- Infectobesity: a New Area for Microbiological and Virological Research
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Na HN, Nam JH
- KMID: 2168623
- J Bacteriol Virol.
- 2011 Jun;41(2):65-76.
- doi: 10.4167/jbv.2011.41.2.65
Obesity is connected with numerous diseases, such as type 2 diabetes, atherosclerosis, cancer, and nervous system dysfunctions. Obesity is affected by genetic, environmental, and cultural factors. However, numerous studies indicate... -
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- Effect of combinatorial bone morphogenetic protein 2 and bone morphogenetic protein 7 gene delivery on osteoblastic differentiation
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Bae Y, Kim KH, Kim SH, Lee CW, Koo KT, Kim TI, Seol YJ, Ku Y, Rhyu IC, Chung CP, Lee YM
- KMID: 2321654
- J Korean Acad Periodontol.
- 2009 Aug;39(Suppl):279-286.
PURPOSE: Gene therapy (ex vivo) has recently been used as a means of delivering bone morphogenetic proteins (BMPs) to sites of tissue regeneration. In the present study, we investigated the... -
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- Human Adenovirus Type 5 as a Delivery Vector is Not Neutralized in Field Serum Samples of Cattle, Pig, and Goat of Republic of Korea
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Kim SM, Lee HS, Lee KN, Park JH, Ko YJ, Kim B
- KMID: 1726977
- J Bacteriol Virol.
- 2014 Sep;44(3):269-273.
- doi: 10.4167/jbv.2014.44.3.269
Human adenovirus type 5 (hAd5) vectors have been demonstrated to be useful vehicles for gene expressions in animals. However, it has not been reported whether hAd5 transduction might be hampered... -
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- Construction of Recombinant p53 Adenovirus ( Ad5CMVp53 ) for Cervical Cancer Gene Therapy
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An WS, Han YJ, Cho SD, Kim JW, Lee JM, Namkoong S, Kim SJ, Kim JK, Park YS, Yang JM, Park SH
- KMID: 2260966
- Korean J Obstet Gynecol.
- 1998 May;41(5):1384-1392.
Human papillomavirus (HPV) has been identified in the majority of invasive cervical cancer patient and has been found to contribute in a significant way to the genesis of human cervical... -
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- Synergistic growth inhibition by combination of adenovirus mediated p53 transfer and cisplatin in ovarian cancer cell lines
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Ryu SY, Kim K, Lee WS, Kwon HC, Lee KH, Kim CM, Kang SB
- KMID: 2055649
- J Gynecol Oncol.
- 2009 Mar;20(1):48-54.
- doi: 10.3802/jgo.2009.20.1.48
OBJECTIVE: This study was to investigate the synergistic growth inhibitory effect by combination of adenovirus mediated p53 gene transfer and cisplatin in ovarian cancer cell lines with different p53 gene... -
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- Models of Experimental Brain Tumors
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Ha YS
- KMID: 2068178
- J Korean Neurosurg Soc.
- 1984 Jun;13(2):237-244.
Despite concentrated basic and clinical research efforts including the initial successful combination of surgery, radiotherapy and chemotherapy with BCNU, significant progress in the treatment of human brain tumors have been... -
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- Novel Role of Invariant Natural Killer T-cell in Glycemic Control: Regulation by human Adenovirus 36
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Park S, Nam JH
- KMID: 2286277
- J Bacteriol Virol.
- 2013 Sep;43(3):229-232.
- doi: 10.4167/jbv.2013.43.3.229
Obesity is associated with a state of chronic low-grade inflammation. This abnormal inflammation state may cause metabolic dysfunction. Many studies have supported the claim that immune cells such as adipose... -
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- The Yesterday, Today, and Tomorrow of Pathogen-induced Obesity
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Na HN, Nam JH
- KMID: 2271025
- Korean J Obes.
- 2013 Dec;22(4):187-196.
The American Medical Association officially declared obesity a disease. However, obesity is caused by genetic, social, environmental, and physiological factors. Among the many factors, infection by some pathogens has a... -
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- Effects of Integrin avB5 and av B53 on the Adenovirus - Mediated Gene Transduction
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Park JY, Joo SY, Jeon HS, Chang HJ, Kam S, Kim IS
- KMID: 2175115
- J Korean Cancer Assoc.
- 2000 Apr;32(2):422-430.
PURPOSE: Human adenovirus, commonly used as a vector for gene therapy, enters host cells by receptor mediated endocytosis. Since integrin av B5 of cell surface promotes endocytosis of adenovirus and subsequent disruption... -
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- Epidemiological Investigation of the Outbreak of Acute Respiratory Infection caused by Adenovirus Type B55 in a Physical Education School in 2017
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Song J, Lee H, Cho E
- KMID: 2450868
- Infect Chemother.
- 2019 Jun;51(2):119-129.
- doi: 10.3947/ic.2019.51.2.119
BACKGROUND: On May 19, 2017, the cluster of 6 acute respiratory infections due to adenovirus in the swimming department of a physical education school (School J) was reported to Korea... -
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- Distribution and Characterization of Airborne Respiratory Pathogens in Public Facilities
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Hwang SJ, Yun HC, Ku PT, Sim JH, Cha YW, Lee MO
- KMID: 2452064
- J Bacteriol Virol.
- 2018 Dec;48(4):121-129.
- doi: 10.4167/jbv.2018.48.4.121
Respiratory infections, which are caused by airborne pathogens, are the most common disease of all ages worldwide. This study was conducted to characterize the airborne respiratory pathogens in the public... -
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- Identification of Viral Pathogens for Lower Respiratory Tract Infection in Children at Seoul During Autumn and Winter Seasons of the Year of 2008-2009
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Kim KH, Kim JH, Kim KH, Kang C, Kim KS, Chung HM, Kim DS
- KMID: 2278957
- Korean J Pediatr Infect Dis.
- 2010 Jun;17(1):49-55.
PURPOSE: The Purposes of this study are to identify the circulating etiologic viruses of acute lower respiratory tract infection in children and to understand the relation with clinical diagnosis. METHODS: We... -
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- Countering the Effects of Chronic Inflammation in Obesity
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Dhurandhar NV
- KMID: 2271086
- Korean J Obes.
- 2014 Jun;23(2):73-78.
Obesity is linked with a chronic low grade inflammation of non-infectious origin, typically marked by a preponderance of inflammatory cytokines, and a reduced presence of anti-inflammatory cytokines in adipose tissue... -
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- Adenovirus-mediated p53 tumor suppressor gene therapy against subcutaneous HuH7 hepatoma cell line nodule of nude mice
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Choi JY, Park YM, Byun BH, Kim BS, Hong EG, Shin DY, Seong YR, Im DS
- KMID: 646305
- J Korean Med Sci.
- 1999 Jun;14(3):271-276.
- doi: 10.3346/jkms.1999.14.3.271
Mutations of the tumor-suppressor gene p53 have been found in 30-50% cases of hepatocellular carcinoma (HCC). In this study, E1-negative adenoviral vector encoding wild-type p53 under the control of the... -
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- Potentials and limitations of adenovirus-p53 gene therapy for brain tumors
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Hong YK, Joe YA, Yang YJ, Lee KS, Son BC, Jeun SS, Chung DS, Cho KK, Park CK, Kim MC, Kim HK, Yung WK, Kang JK
- KMID: 1128631
- J Korean Med Sci.
- 2000 Jun;15(3):315-322.
- doi: 10.3346/jkms.2000.15.3.315
We investigated the antineoplastic potentials of recombinant adenovirus containing wild-type p53 cDNA (Ad5CMV-p53) for malignant gliomas. In four human glioma cell lines (U-251 and LG expressing endogenous mutant p53, and... -
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- Active Surveillance of Pertussis in Infants Under 6 Months of Age: A Single Center Experience from 2011 to 2013
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Han YI, Choi JY, Lee H, Lee TJ
- KMID: 1720814
- Korean J Pediatr Infect Dis.
- 2014 Aug;21(2):114-120.
PURPOSE: The objective of this study was to assess and investigate the epidemiology of pertussis in infants under 6 months of age. METHODS: A prospective study was conducted between October 1,... -
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- Distribution of Adenoviral Vector in Brain after Intravenous Administration
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Jin JY, Moon CI, Moon CI, Kang WS, Jeong DC
- KMID: 1099803
- J Korean Med Sci.
- 2003 Feb;18(1):108-111.
- doi: 10.3346/jkms.2003.18.1.108
The delivery of transgenes to the central nervous system (CNS) can be a valuable tool to treat CNS diseases. Various systems for the delivery to the CNS have been developed;... -
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