Korean J Pathol.  2013 Jun;47(3):299-303.

Imprint Cytology of Soft Tissue Myoepithelioma: A Case Study

Affiliations
  • 1Department of Pathology, Yeungnam University College of Medicine, Daegu, Korea. joonhyukchoi@ynu.ac.kr
  • 2Department of Orthopedic Surgery, Yeungnam University College of Medicine, Daegu, Korea.

Abstract

Soft tissue myoepithelioma is a rare neoplasm composed of myoepithelial cells. Here, we describe the cytologic features of soft tissue myoepithelioma arising on the right forearm in an 18-year-old man. The excised tumor (3.0x1.8x1.5 cm) was well-demarcated, yellow-gray, soft, and myxoid. The cytologic smears showed round to spindle, epithelioid, and plasmacytoid cells in the myxoid background. The nuclei were uniform, round to ovoid, with finely distributed chromatin and eosinophilic or pale cytoplasm. The tumor cells demonstrated immunoreactivity for cytokeratin (AE1/AE3), epithelial membrane antigen, S100 protein, and glial fibrillary acidic protein. Electron microscopy showed intermediate filaments, desmosomes, and basal lamina.

Keyword

Soft tissue; Myoepithelioma; Cytology

MeSH Terms

Basement Membrane
Chromatin
Cytoplasm
Desmosomes
Eosinophils
Forearm
Glial Fibrillary Acidic Protein
Intermediate Filaments
Keratins
Microscopy, Electron
Mucin-1
Myoepithelioma
Chromatin
Glial Fibrillary Acidic Protein
Keratins
Mucin-1
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