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Anaplastic Transformation of Metastatic Papillary Thyroid Carcinoma in a Cervical Lymph Node: a Timeline and Short Review

Cinamon U, Horev Y, Vaknine H

Anaplastic thyroid cancer (ATC) is accepted as the transformation of a pre-existing glandular papillary thyroid carcinoma (PTC). Anaplastic transformation of a neck PTC metastasis in a lymph node is extraordinary....
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Bilateral Breast Metastases from Epstein-Barr Virus-Associated Gastric Cancer during Pregnancy: Is There a Method to Its Madness?

Quaquarini E, Vanoli A, Frascaroli M, Viglio A, Lucioni M, Presti D, Lobascio G, Pietrabissa A, Bernardo A, Paulli M

Breast metastases of extramammary malignant neoplasms are rare, with an incidence of 0.3%–2.7% among all malignant mammary tumors. Breast metastases from gastric carcinoma are very rare (
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Diagnostic Value of CYFRA 21-1 Measurement in Fine-Needle Aspiration Washouts for Detection of Axillary Recurrence in Postoperative Breast Cancer Patients

Won SY, Kim EK, Moon HJ, Yoon JH, Park VY, Kim MJ

PURPOSE: The objective of this study was to evaluate the diagnostic value and threshold levels of cytokeratin fragment 21-1 (CYFRA 21-1) in fine-needle aspiration (FNA) washouts for detection of lymph...
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Clear cell odontogenic carcinoma: a mini review

Kim YH, Seo EJ, Park JK, Jang IH

Clear cell odontogenic carcinoma (CCOC), a very rare neoplasm located mostly in the mandible, has been regarded as a benign tumor. However, due to the accumulation of case reports, CCOC...
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A Report of Bone Marrow Metastasis of Colon Cancer as a Primary Diagnosis, Supported by Cytokeratin Immunohistochemical Staining

Kim B, Lee KT

Bone marrow metastasis of colon cancer is rare. Here, we report a 56-year-old female patient who presented with pancytopenia. She was diagnosed with colon cancer accompanied by lung and axial...
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Primary Malignant Melanoma of the Breast: A Report of Two Cases

Koh J, Lee J, Jung SY, Kang HS, Yun T, Kwon Y

Primary malignant melanoma of the breast (PMMB) is a rare tumor with only a few case reports available in the literature. We report two cases of PMMB, one derived from...
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Squamous Cell Carcinoma of the Extrahepatic Common Hepatic Duct

Kang M, Kim NR, Chung DH, Cho HY, Park YH

We report a rare case of hilar squamous cell carcinoma. A 62-year-old Korean woman complaining of nausea was referred to our hospital. Her biliary computed tomography revealed a 28 mm-sized...
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A renal oncocytoma in a Maltese dog with renal cysts

Kim JU, Park J, Kim G, Chang D, Ahn B

A renal oncocytoma was diagnosed in an 8-year-old female Maltese dog with a history of renal cysts. Tumor cells were not detected until six months after observation of renal cysts....
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Pathologic differential diagnosis of metastatic carcinoma in the liver

Park JH, Kim JH

The liver is one of the most common sites to which malignancies preferentially metastasize. Although a substantial number of liver malignancies are primary tumors, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma,...
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A large thymic mass with persistent active tissue in an elderly cadaver

Tripathy P, Chaudhary , Gaikwad MR, Britto NJ

Thymus is an encapsulated organ having its bilateral origin from the third pharyngeal pouch. It appears to be a single organ but actually it is bilobed. It attains its maximum...
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A Nasal Myoepithelioma Removed through Preoperative Embolization and Endoscopic Surgery: A Case Report and Literature Review

Kang JW, Im SK, Song CE, Jung SY

Myoepithelioma is a rare benign tumor, most frequently located in the salivary gland. However, involvement of an extra-salivary gland is even rarer and very few cases involving the nasal cavity...
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Beta-Catenin Downregulation Contributes to Epidermal Growth Factor-induced Migration and Invasion of MDAMB231 Cells

Kwon A, Park HJ, Baek JH

We previously demonstrated that epidermal growth factor (EGF) enhances cell migration and invasion of breast cancer cells in a SMAD ubiquitination regulatory factor 1 (SMURF1)-dependent manner and that SMURF1 induces...
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Necessity of In Situ Hybridization Test of Human Epidermal Growth Factor Receptor 2 (HER2) Status in Breast Cancer Patients with Equivocal HER2 Immunohistochemistry Results

Paik HJ, Choi HJ, Ryu JM, Park S, Kim I, Lee SK, Yu J, Kim SW, Nam SJ, Lee JE

PURPOSE: Accurate human epidermal growth factor receptor 2 (HER2) status is important in predicting prognosis and providing treatment for HER2-positive breast cancer patients. However, performing in situ hybridization (ISH) can...
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Investigation of Immune-Regulatory Effects of Mageumsan Hot Spring via Protein Microarray In Vitro

Hahn HJ, Kim JS, Kim YH, Lee YB, Yu DS, Kim JW

BACKGROUND: Empirical evidences for efficacy of hot spring (HS) water in inflammatory skin disorders have not been substantiated with sufficient, immunological “hard evidence”. Mageumsan HS water, characterized by its weakly-alkaline...
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Mammary Paget's disease without underlying malignancy of the breast

Jang N, Kang S, Bae YK

Mammary Paget's disease (MPD) is usually accompanied by underlying breast malignancy; however, a few cases have been reported as only skin lesions without any evidence of malignancy of the breast...
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Seromucinous component in endometrioid endometrial carcinoma as a histological predictor of prognosis

Miyamoto M, Takano M, Aoyama T, Soyama H, Yoshikawa , Tsuda H, Furuya K

OBJECTIVE: In 2014 World Health Organization criteria, seromucinous carcinoma was defined as a new histological subtype in ovarian carcinomas, but “seromucinous carcinoma” was not defined in endometrial carcinomas. The aim...
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Colloid Carcinoma of the Uterine Cervix and Its Immunohistochemical Analysis: A Case Report

Koc N, Arinkan SA, Ozbay NO, Selcuk S

Colloid carcinoma, which is a very rare tumor of the uterine cervix, is composed of an excessive amount of mucus and a relative paucity of tumoral glandular cells within them....
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Angiomyolipoma of the Liver without a Fat Component, Mimicking a Hepatocellular Carcinoma

Woo YM, Ryu SH, Min JW, Kim MR, Park TY, Moon JS, Kang YK

Angiomyolipoma (AML) is a rare benign mesenchymal tumor in the liver, which is composed of blood vessels, smooth muscle, and adipose cells. The proportion of each component varies, making a...
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Cytokeratin 13, Cytokeratin 17, and Ki-67 Expression in Human Acquired Cholesteatoma and Their Correlation With Its Destructive Capacity

Hamed MA, Nakata S, Shiogama K, Suzuki K, Sayed RH, Nishimura , Iwata N, Sakurai K, Badawy BS, Inada K, Tsuge H, Tsutsumi Y

OBJECTIVES: Cholesteatoma is a nonneoplastic destructive lesion of the temporal bone with debated pathogenesis and bone resorptive mechanism. Both molecular and cellular events chiefly master its activity. Continued research is...
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The Detection of Messenger RNA for Carcinoembryonic Antigen and Cytokeratin 20 in Peritoneal Washing Fluid in Patients with Advanced Gastric Cancer

Kim YJ, Chung WC, Choi S, Jung YD, Lee J, Chae SY, Jun KH, Chin HM

BACKGROUND/AIMS: Peritoneal micrometastasis is known to play an important role in the recurrence of gastric cancer. However, its effects remain equivocal. Herein, we examine the messenger RNA (mRNA) as tumor...
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