Korean J Dermatol.  2008 Feb;46(2):245-248.

A Case of Milium-like Syringoma on Vulva

Affiliations
  • 1Department of Dermatology, College of Medicine, Dong-A University, Busan, Korea. mucca@hanmail.net

Abstract

Milium-like syringoma is a rare variant of syringoma first described by Friedman and Butler in 1987. Clinically, it presents as milium, but histologically reveals syringoma with overlying keratin filled epidermoid cysts. It occurs predominantly on the periorbital area of middle-aged women. Syringomas on the genital area have rarely been reported. The lower portion of the cysts and keratin materials show positivity for CEA and negativity for CK7. The pathogenesis is not well defined, but there are some hypotheses, which include pruritus and increasing hormonal receptors (estrogen and progesterone receptors). We report a case of milium-like syringoma on the vulva.

Keyword

Milium-like syringoma; Vulva

MeSH Terms

Epidermal Cyst
Female
Humans
Keratins
Progesterone
Pruritus
Syringoma
Vulva
Keratins
Progesterone
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