Korean J Med.  2016 Apr;90(4):361-364. 10.3904/kjm.2016.90.4.361.

Healthcare-associated Endocarditis by PVL-negative ST 72 SCCmec Type IV MRSA

Affiliations
  • 1Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. helppl@hallym.ac.kr
  • 2Department of Laboratory Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.

Abstract

The prevalence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been increasing worldwide. In Korea, the most common genotype of CA-MRSA is the Panton-Valentine leukocidin-negative, sequence type 72 Staphylococcal cassette chromosome (SCC) mec type IV clone. However, within Korean hospitals, this strain is still not commonly reported. In this study, we describe a case of infective endocarditis caused by Panton-Valentine leukocidin-negative MRSA (ST72-SCCmec type IV A clone). Infection occurred after open reduction and internal fixation due to a right humerus fracture with cerebral hemorrhage. Initially, the patient was treated with linezolid, but with the onset of severe thrombocytopenia, the patient was switched to vancomycin therapy.

Keyword

Methicillin-resistant staphylococcus aureus; Endocarditis; Linezolid

MeSH Terms

Cerebral Hemorrhage
Clone Cells
Endocarditis*
Genotype
Humans
Humerus
Korea
Methicillin-Resistant Staphylococcus aureus*
Prevalence
Thrombocytopenia
Vancomycin
Linezolid
Vancomycin
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