Korean J Med.
2009 Sep;77(3):367-370.
Two patients with acquired hemophilia successfully treated with combination therapy including therapeutic plasmapheresis
- Affiliations
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- 1Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea. lisa1114@naver.com
- 2Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Abstract
- Acquired hemophilia is a rare disorder associated with fatal bleeding caused by the development of autoantibodies against factor VIII. Here, we report the cases of two young women with acquired hemophilia who presented with massive internal hemorrhage and purpura. Both patients were successfully treated with combination therapy including factor VIII or factor VIII bypassing agent, immunosuppressants, and therapeutic plasmapheresis.
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