Korean J Intern Med.
2000 Jul;15(2):135-137.
Acquired hemophilia successfully treated with oral immunosuppressive therapy
- Affiliations
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- 1Department of Internal Medicine, Chonnam National University Medical School, Kwangju, Korea.
- 2Department of Clinical Pathology, Chonnam National University Medical School, Kwangju, Korea.
Abstract
- Acquired hemophilia is a rare disorder associated with serious bleeding in nonhemophilic patients. We had a 40-year-old woman who was diagnosed as acquired hemophilia with a factor VIII inhibitor level of 27.5 BU/mL. She was presented with gross hematuria and severe right shoulder pain, and was successfully treated with daily oral cyclophosphamide and prednisone for 2 weeks. After the remission, the doses of prednisone and cyclophosphamide were slowly decreased and she remained in complete remission without further bleeding episodes.
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