Korean J Med.  2003 Nov;65(Suppl 3):S767-S772.

A case of parathyroid carcinoma with meningioma

• Ju HS
• Koh JH
• Hong TW
• Shim MS
• Kim MJ
• Lee KG
• Chung CH

Abstract

Parathyroid carcinoma is a very rare disease which comprising 0.1~5% of hyperparathyroidism, and it usually presents with marked hypercalcemia. Clinically, it shows hypercalcemia due to the effect of excessive secretion of parathyroid hormone, bone disease, renal involvement and palpable neck mass. It is known that hyperparathyroidism is induced mostly by parathyroid adenoma but it can be seen in parathyroid hyperplasia, hyperparathyroid carcinoma, rarely associated with familial or multiple endocrine neoplasia. Parathyroid carcinoma can be diagnosed with distant metastasis or local invasion. Treatment is complete resection of primary cancerous lesion and local tissue. Since recurrence or distant metastases are frequent, radiological studies should be done when hypercalcemia is recurred. Sometimes, other tumors can causes hypercalcemia. There are several reports of parathyroid cancer associated with multiple endocrine neoplasia, but has never been reported of parathyroid carcinoma associated with meningioma. We experienced a parathyroid carcinoma with meningioma in 68 year old woman and report the case with the review of literatures.

Keyword

Parathyroid Neoplasms; Meningioma; Hypercalcemia

MeSH Terms

Aged
Bone Diseases
Female
Humans
Hypercalcemia
Hyperparathyroidism
Hyperplasia
Meningioma*
Multiple Endocrine Neoplasia
Neck
Neoplasm Metastasis
Parathyroid Hormone
Parathyroid Neoplasms*
Rare Diseases
Recurrence
Parathyroid Hormone