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Inhibitory Effect of Rosae Multiflorae Fructus Extracts on the Receptor Activator of NF-κB Ligand-Induced Osteoclastogenesis through Modulation of P38- and Ca2⁺-Mediated Nuclear Factor of Activated T-Cells Cytoplasmic 1 Expression

Park KH, Gu DR, Kim MS, Lee SH

BACKGROUND: Rosae Multiflorae fructus (RMF), known to have anti-inflammatory and antioxidant properties, has been used as a traditional remedy for inflammatory diseases such as arthritis in Eastern Asia. However, its...
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The association of potassium intake with bone mineral density and the prevalence of osteoporosis among older Korean adults

Ha J, Kim SA, Lim K, Shin S

BACKGROUND/OBJECTIVES: Osteoporosis is characterized by low bone mass and results in vulnerability to fracture. Calcium and vitamin D are known to play an important role in bone health. Recently, potassium...
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Hypertrophic osteopathy in a cat with cardiac interventricular septal defect

de Sousa F, Bianchi MV, Taunde PA, Bandinelli MB, Fett RR, Driemeier , Pavarini S

A 3-year-old mixed-breed female cat was diagnosed with a ventricular septal defect of the heart through an echocardiogram. After a 9-month treatment, progressive and diffuse hard thickening of all limbs...
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A comparison of 6 osteoporosis risk assessment tools among postmenopausal women in Kuala Lumpur, Malaysia

Toh LS, Lai PS, Wu DB, Bell BG, Dang CP, Low BY, Wong KT, Guglielmi , Anderson C

OBJECTIVES: To compare and assess the performance of 6 osteoporosis risk assessment tools for screening osteoporosis in Malaysian postmenopausal women. METHODS: Six osteoporosis risk assessments tools (the Simple Calculated Osteoporosis Risk...
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Piperlongumine suppressed osteoclastogenesis in RAW264.7 macrophages

Jin SM, Kang HM, Park DB, Yu SB, Kim IR, Park BS

Piperlongumine (PL) is a natural product found in long pepper (Piper longum). The pharmacological effects of PL are well known, and it has been used for pain, hepatoprotection, and asthma...
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Anorexia Nervosa and Osteoporosis: Pathophysiology and Treatment

Steinman J, Shibli-Rahhal A

Anorexia nervosa (AN) affects 2.9 million people, many of whom experience bone loss and increased fracture risk. In this article, we review data on the underlying pathophysiology of AN-related osteoporosis...
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Relationship between the Progression of Kyphosis in Thoracolumbar Osteoporotic Vertebral Compression Fractures and Magnetic Resonance Imaging Findings

Jun DS, Baik JM, Kwon HM

PURPOSE: To examine the relationship between the progression of a kyphotic deformity and the magnetic resonance imaging (MRI) findings in conservatively treated osteoporotic thoracolumbar compression fracture patients. MATERIALS AND METHODS: This...
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Short Bowel Syndrome as the Leading Cause of Intestinal Failure in Early Life: Some Insights into the Management

Goulet O, Abi Nader , Pigneur B, Lambe C

Intestinal failure (IF) is the critical reduction of the gut mass or its function below the minimum needed to absorb nutrients and fluids required for adequate growth in children. Severe...
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Diabetes and bone

Hygum K, Starup-Linde J, Langdahl B

Bone disease is a serious complication to diabetes. Patients with type 1 diabetes (T1D) and type 2 diabetes (T2D) suffer from an increased risk of fracture, most notably at the...
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Simultaneous Estimation of the Fat Fraction and Râ‚‚* Via Tâ‚‚*-Corrected 6-Echo Dixon Volumetric Interpolated Breath-hold Examination Imaging for Osteopenia and Osteoporosis Detection: Correlations with Sex, Age, and Menopause

Kim D, Kim SK, Lee SJ, Choo HJ, Park JW, Kim KY

OBJECTIVE: To investigate the relationships of T2 *-corrected 6-echo Dixon volumetric interpolated breath-hold examination (VIBE) imaging-based fat fraction (FF) and R2 * values with bone mineral density (BMD); determine their associations with...
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Effects of Parity and Breastfeeding Duration on Bone Density in Postmenopausal Women

Lee EN

PURPOSE: This study aimed to identify the effect of parity and breastfeeding duration and the occurrence of lumbar vertebral and femoral neck osteoporosis in Korean postmenopausal women. METHODS: This study analyzed...
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Extracts of Flavoparmelia sp. Inhibit Receptor Activator of Nuclear Factor-κB Ligand-Mediated Osteoclast Differentiation

Kim KJ, Lee Y, Jeong MH, Hur JS, Son YJ

BACKGROUND: Osteoporosis is a geriatric disease with diminished bone density. The increase in the number of patients and medical expenses due to a global aging society are recognized as problems....
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Increased Risk of Osteoporosis in Gastric Cancer Survivors Compared to General Population Control: A Study with Representative Korean Population

Jeong SM, Shin DW, Lee JE, Jin SM, Kim S

PURPOSE: Although several studies have suggested that osteoporosis is common in survivors of gastric cancer (GC), no study to date has directly assessed the risk for osteoporosis in GC survivors...
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Association between Body Fat and Bone Mineral Density in Normal-Weight Middle-Aged Koreans

Kim DH, Lim H, Chang S, Kim JN, Roh YK, Choi MK

BACKGROUND: Osteoporosis and osteopenia are characterized by reduced bone mineral density (BMD) and increased fracture risk. Although the risk of fractures is higher in underweight people than in overweight people,...
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Risks and benefits of menopausal hormone therapy

Yoon BK

Menopausal hormone therapy (MHT) was widely used to improve quality of life by controlling menopausal symptoms, including vasomotor symptoms and urogenital atrophy. Furthermore, observational studies consistently reported beneficial effects of...
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Effects of Thyrotropin Suppression on Bone Health in Menopausal Women with Total Thyroidectomy

Kim EH, Jeon YK, Pak K, Kim IJ, Kim SJ, Shin S, Kim BH, Kim SS, Lee BJ, Lee JG, Goh TS, Kim K

BACKGROUND: This study examined the change in the trabecular bone score (TBS), areal bone mineral density (aBMD), and osteoporosis in postmenopausal women who underwent thyrotropin (TSH)-suppressive therapy for treating papillary...
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Effect of Vitamin D on Bone Mineral Density Changes in Patients with Breast Cancer Receiving Adjuvant Aromatase Inhibitor Therapy

Park SH, Kim EY, Park CH

PURPOSE: We assessed bone mineral density (BMD) changes with aromatase inhibitor (AI) treatment in women with breast cancer and determined whether BMD T-scores changed with vitamin D supplementation. METHODS: This single-center,...
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Efficacy of zoledronic acid in older prostate cancer patients undergoing androgen deprivation therapy

Kojima I, Naito Y, Yamamoto A, Terashima , Sho N, Nagayama J, Okada Y, Nagai T

OBJECTIVES: The purpose of this study is to evaluate the efficacy of annual zoledronic acid treatment in Japanese patients with nonmetastatic prostate cancer during androgen deprivation therapy (ADT). METHODS: This is...
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Outcomes following Treatment of Geriatric Distal Femur Fractures with Analyzing Risk Factors for the Nonunion

Jeong SY, Lee JH, Park KC

PURPOSE: Many international journals have published studies on the results of distal femoral fractures in elderly people, but only a few studies have been conducted on the Korean population. The...
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Giant Cell Reparative Granuloma in the Temporal Bone of a 4-Month-Old Infant

Choi Y, Chung JW

Giant cell reparative granuloma (GCRG) is a rare benign bone disease of unknown causes. Trauma is a suspected cause or contributor to the onset of GCRG, of which only a...
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