J Bone Metab.  2017 Nov;24(4):201-206. 10.11005/jbm.2017.24.4.201.

Bone Density Status in Bleeding Disorders: Where Are We and What Needs to Be Done?

• Mansouritorghabeh H
• Rezaieyazdi Z

• KMID: 2397552
• DOI: http://doi.org/10.11005/jbm.2017.24.4.201

Abstract

Bleeding disorders, including hemophilia, can be seen in every ethnic population in the world. Among various bleeding disorders, reduced bone density has been addressed in hemophilia A. In recent years, there has been an increasing interest in addressing osteopenia and osteoporosis in hemophilia A. There is little or no study about the possible susceptibility of other individuals with bleeding disorders to reduced bone density. Questions have been raised about the role of blood coagulation factors in bone mineralization. This review provides new insight and ideas for further survey in the field of bleeding disorders and reduced bone density.

Keyword

Hemophilia A; Hemophilia B; Osteoporosis; Reduced bone density; von Willebrand diseases

MeSH Terms

Blood Coagulation Factors
Bone Density*
Bone Diseases, Metabolic
Calcification, Physiologic
Hemophilia A
Hemophilia B
Hemorrhage*
Osteoporosis
von Willebrand Diseases
Blood Coagulation Factors