Endocrinol Metab.  2018 Mar;33(1):133-134. 10.3803/EnM.2018.33.1.133.

An Unusual Case of Meningioma Showing Increased CaSR Expression with Parathyroid Carcinoma

Affiliations
  • 1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. cchung@yonsei.ac.kr
  • 2Department of Medicine, Korea University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea.

Abstract

No abstract available.


MeSH Terms

Meningioma*
Parathyroid Neoplasms*

Figure

  • Fig. 1 Computed tomography scan of the neck showing 1×1.2 cm sized left cervical mass with low density, consistent with recurrent parathyroid carcinoma (arrow). Adapted from Ju et al. [1].

  • Fig. 2 (A) Magnetic resonance imaging of the meningioma. A 3×4 cm sized extra-axial tumor along the left frontal convexity consistent with meningioma is noted (arrow). Adapted from Ju et al. [1]. (B) Immunohistochemical localization of calcium sensing receptor (CaSR) in meningioma. Strong CaSR-antibody (diluted 1:500, Novus Biologicals) reactivity in meningioma tissue is notable (×200).


Reference

1. Ju HS, Koh JH, Hong TW, Shim MS, Kim MJ, Lee KG, et al. A case of parathyroid carcinoma with meningioma. Korean J Med. 2003; 65:Suppl 3. S767–S772.
2. Saidak Z, Mentaverri R, Brown EM. The role of the calcium-sensing receptor in the development and progression of cancer. Endocr Rev. 2009; 30:178–195.
Article
3. Brennan SC, Thiem U, Roth S, Aggarwal A, Fetahu ISh, Tennakoon S, et al. Calcium sensing receptor signalling in physiology and cancer. Biochim Biophys Acta. 2013; 1833:1732–1744.
Article
4. Chattopadhyay N, Evliyaoglu C, Heese O, Carroll R, Sanders J, Black P, et al. Regulation of secretion of PTHrP by Ca(2+)-sensing receptor in human astrocytes, astrocytomas, and meningiomas. Am J Physiol Cell Physiol. 2000; 279:C691–C699.
5. Kim YL, Jang YW, Kim JT, Sung SA, Lee TS, Lee WM, et al. A rare case of primary hyperparathyroidism associated with primary aldosteronism, Hurthle cell thyroid cancer and meningioma. J Korean Med Sci. 2012; 27:560–564.
6. Marini F, Falchetti A, Del Monte F, Carbonell Sala S, Gozzini A, Luzi E, et al. Multiple endocrine neoplasia type 1. Orphanet J Rare Dis. 2006; 1:38.
Full Text Links
  • ENM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr