J Korean Soc Ther Radiol Oncol.  2010 Jun;28(2):111-116. 10.3857/jkstro.2010.28.2.111.

Nonfunctional Parathyroid Carcinoma: A Case Report

• Choi SG

• KMID: 1460160
• DOI: http://doi.org/10.3857/jkstro.2010.28.2.111

Abstract

Parathyroid carcinoma is a rare endocrine malignancy accounting for 0.5% to 4.0% of all cases of hyperparathyroidism and commonly present as hypercalcemia and parathyroid hormone (PTH) elevation. Nonfunctional parathyroid carcinoma does not show symptoms of hyperparathyroidism and only showed a vague indication of being pathologic, even when detected late. The optimal treatment is en bloc resection of the cancer, but frequent local recurrence after surgery has been reported. Adjuvant local treatment such as radiotherapy may improve the likelihood local control in cases with incompletely resected or microscopic residual tumor. The results of this study point to a case of nonfunctional parathyroid carcinoma treated by external beam radiotherapy after en-bloc resection of cancer.

Keyword

Nonfunctional parathyroid carcinoma; Radiotherapy

MeSH Terms

Accounting
Hypercalcemia
Hyperparathyroidism
Neoplasm, Residual
Parathyroid Hormone
Parathyroid Neoplasms
Recurrence
Parathyroid Hormone