J Endocr Surg.  2022 Dec;22(4):123-126. 10.16956/jes.2022.22.4.123.

Benign Recurrent Primary Hyperparathyroidism After Parathyroid Carcinoma

• Jeoffrey SMH
• McCoy KL
• Gibson CE

• KMID: 2538526
• DOI: http://doi.org/10.16956/jes.2022.22.4.123

Abstract

This report describes the rare occurrence of a parathyroid adenoma 15 years after the resection of a right-sided parathyroid carcinoma, with recurrence of clinical manifestations of hyperparathyroidism. We report the case of a 41-year-old female who returned to the clinic with bone pain, memory difficulties and fatigue. After a thorough assessment, a hyperechoic nodule of parathyroid origin was detected and resected. The resected lesion was located inferior to the left thyroid lobe, measuring 1.3×0.7×0.6 cm and weighing 602 mg; histopathology was consistent with a parathyroid adenoma. Recurrent primary hyperparathyroidism due to benign adenoma, after prior surgery for parathyroid carcinoma, is a rare phenomenon. Early recognition, diagnosis and intervention are essential to prevent and/or reduce associated morbidity and mortality.

Keyword

Primary hyperparathyroidism; Parathyroid carcinoma