Korean J Head Neck Oncol.  2022 May;38(1):25-29. 10.21593/kjhno/2022.38.1.25.

A Case of Parathyroid Carcinoma with Spontaneous Infarction

Affiliations
  • 1Department of Otorhinolaryngology Head and Neck Surgery, Daegu Catholic University School of Medicine, Daegu, Korea

Abstract

Parathyroid carcinoma is very rare malignant neoplasm, accounting for less than 0.005% of all cancers. Most parathyroid carcinoma is a functioning tumor that causes hyperparathyroidism, leading to hypercalcemia. We report a parathyroid carcinoma case that was suspicious for spontaneous infarction of cancer, leading to resolution of hypercalcemia. A 29-year-old male visited our hospital presenting with right neck swelling and pain. He has been experiencing frequent urolithiasis for four years but laboratory tests showed normal serum calcium level. Right vocal cord paresis was identified with laryngoscopy. Ultrasonography revealed a 3.7 × 3.5 cm mass in the right thyroid containing a focal cystic portion. Computed tomography confirmed the presence of a low-density right thyroid mass. Right thyroid lobectomy was performed and pathological evaluation revealed parathyroid carcinoma with central necrosis. We report this very rare case with a literature review.

Keyword

Necrosis; Parathyroid neoplasms; Parathyroid cancer; Parathyroid glands
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