Korean J Med.
1997 Sep;53(3):431-435.
A Case of Methotrexate Induced Liver Cirrhosis
Abstract
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Methotrexate has been used to treat refractory psoriasis for many years. Despite its well-established clinical efficacy, drawbacks to methotrexate usage include a number of deleterious effects including hepatotoxicity, bone marrow suppression, and interstitial pneumonitis. We experienced a case of liver cirrhosis m patient with active psoriasis receiving long-term ora1 methotrexate therapy, and reported this case with review of literature.