Korean J Med.  1997 Sep;53(3):431-435.

A Case of Methotrexate Induced Liver Cirrhosis

Abstract

Methotrexate has been used to treat refractory psoriasis for many years. Despite its well-established clinical efficacy, drawbacks to methotrexate usage include a number of deleterious effects including hepatotoxicity, bone marrow suppression, and interstitial pneumonitis. We experienced a case of liver cirrhosis m patient with active psoriasis receiving long-term ora1 methotrexate therapy, and reported this case with review of literature.

Keyword

Methotrexate; Psoriasis; Liver cirrhosis

MeSH Terms

Bone Marrow
Humans
Liver Cirrhosis*
Liver*
Lung Diseases, Interstitial
Methotrexate*
Psoriasis
Methotrexate
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