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Impact of liver cirrhosis on the clinical outcomes of patients with COVID-19: a nationwide cohort study of Korea

Jeon D, Son M, Choi J

Background/Aims: The impact of liver cirrhosis (LC) on the clinical outcomes of patients with coronavirus disease 2019 (COVID-19) remains elusive. This study evaluated the association between LC and the development...
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Gastroduodenal artery steal syndrome treated with coil embolization after orthotopic liver transplantation

Vu J, Beltran-Perez J, Bordlee B

Gastroduodenal artery steal syndrome is an uncommon complication occurring after orthotopic liver transplantation (OLT) that results in hypoperfusion of the hepatic artery increasing the risk for graft dysfunction. Its non-specific...
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Direct Bilirubin Is More Valuable than Total Bilirubin for Predicting Prognosis in Patients with Liver Cirrhosis

Lee HA, Jung JY, Lee YS, Jung YK, Kim JH, An H, Yim HJ, Jeen YT, Yeon JE, Byun KS, Um SH, Seo YS

Background/Aims: Most prognostic prediction models for patients with liver cirrhosis include serum total bilirubin (TB) level as a component. This study investigated prognostic performance of serum direct bilirubin (DB) and...
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Hepatopulmonary Syndrome with Finger Clubbing

Kim HK, Kim WK, Kim JH, Lee JW, Chung WJ, Kwon OS, Kim JH

Hepatopulmonary syndrome is a rare lung complication of liver cirrhosis, caused by pulmonary microvascular vasodilation that induces abnormal arterial oxygenation. Typical findings on physical examination are finger clubbing and cyanosis....
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Two-Dimensional Shear Wave Elastography Predicts Liver Fibrosis in Jaundiced Infants with Suspected Biliary Atresia: A Prospective Study

Chen H, Zhou L, Liao B, Cao Q, Jiang H, Zhou W, Wang G, Xie X

Objective: This study aimed to evaluate the role of preoperative two-dimensional (2D) shear wave elastography (SWE) in assessing the stages of liver fibrosis in patients with suspected biliary atresia (BA)...
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Hepcidin Levels and Pathological Characteristics in Children with Fatty Liver Disease

Tsutsumi N, Nishimata S, Shimura M, Kashiwagi Y, Kawashima H

Purpose: Hepcidin levels have previously been reported to be correlated with liver damage.However, the association between hepcidin levels and liver fibrosis in children with fatty liver disease remains unclear. This...
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Partial Virological Response after 2 Years of Entecavir Therapy Increases the Risk of Hepatocellular Carcinoma in Patients with Hepatitis B Virus-Associated Cirrhosis

Shin SK, Yim HJ, Kim JH, Lee CU, Yeon JE, Suh SJ, Jung YK, Kim YS, Kim JH, Kwon OS

Background/Aims: The clinical significance of partial virological response (PVR) in patients undergoing antiviral therapy is not well known. This study investigated whether PVR after 2 years of entecavir (ETV) therapy...
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Management of Patients with Chronic Liver Disease: The Era of the COVID-19 Pandemic

Lee YR

Pandemic of coronavirus disease 2019 (COVID-19) has caused many changes in the healthcare system and patients with preexisting advanced liver disease, notably cirrhosis, are associated with a severe course and...
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A need for patient-centered care in managing patients with liver cirrhosis

Yoon EL

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Association between new-onset liver cirrhosis and suicide risk in South Korea: A nationwide cohort study

Jang SY, Rou WS, Kim SH, Lee BS, Eun HS

Background/Aims: Current evidence suggests that liver cirrhosis (LC) causes severe psychological stress and depression, which are risk factors for suicide. Although previous studies reported the association between LC and suicidal...
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Evaluation and management of extrahepatic manifestations of nonalcoholic fatty liver disease

Wijarnpreecha K, Aby ES, Ahmed A, Kim D

Nonalcoholic fatty liver disease (NAFLD) is a multisystemic disease and a rapidly growing cause of chronic liver disease in children and adults worldwide. Diagnosis and management of extrahepatic manifestations of...
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Comorbidities and Prescribed Medications in Korean Patients with Chronic Hepatitis C: A Nationwide, Population-Based Study

Chung JW, Choi HY, Ki M, Jang ES, Jeong SH

Background/Aims: Extrahepatic comorbidities and comedication are important to consider in the treatment of chronic hepatitis C (CHC) patients with direct-acting antivirals (DAAs) due to the risk of drug-drug interaction (DDI)...
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Environmental risk factors and comorbidities of primary biliary cholangitis in Korea: a case-control study

Kim KA, Kim YS, Park SH, Chung WJ, Choi DH, Jang ES, Jeong SH

Background/Aims: The risk factors for the development of primary biliary cholangitis (PBC) is unclear. This study aimed to investigate the risk factors associated with PBC in Korea through a questionnaire...
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Two Cases of Fungemia after Endoscopic Variceal Obturation for Gastric Variceal Bleeding

Choi SI, Yoon EL

Fever is a common complication of endoscopic variceal obturation (EVO) therapy for gastric variceal bleeding. However, fungemia related to EVO therapy has not yet been reported. Herein, we report two...
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Diffusion-Weighted Imaging for Differentiation of Biliary Atresia and Grading of Hepatic Fibrosis in Infants with Cholestasis

Kim J, Shin HJ, Yoon H, Han SJ, Koh H, Kim MJ, Lee MJ

Objective: To determine whether the values of hepatic apparent diffusion coefficient (ADC) can differentiate biliary atresia (BA) from non-BA or be correlated with the grade of hepatic fibrosis in infants...
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Effectiveness of 4-Week Oral Taurine Treatment for Muscle Cramps in Patients with Liver Cirrhosis: A Single-Arm Pilot Study

Jang ES, Hwang SH, Kim JW, Jeong SH

Purpose: Painful muscle cramps are a common complication in liver cirrhosis patients, and no effective treatment is available. This pilot study aimed to evaluate whether taurine supplementation improves muscle cramps in...
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The cut-off value of transient elastography to the value of hepatic venous pressure gradient in alcoholic cirrhosis

Ryu SR, Yoo JJ, Kang SH, Jeong SW, Kim MY, Cho YK, Chang Y, Kim SG, Jang JY, Kim YS, Baik SK, Kim YJ, Park SY, Baymbajav B

Background/Aims: The hepatic venous pressure gradient (HVPG) reflects portal hypertension, but its measurement is invasive. Transient elastography (TE) is a noninvasive method for evaluating liver stiffness (LS). We investigated the...
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Noninvasive markers for esophageal varices in children with cirrhosis

Rahmani P, Farahmand F, Heidari G, Sayarifard A

Background: The diagnosis of esophageal varices (EV) is based on the findings of esophagogastroduodenoscopy (EGD), biopsy, and serum markers. Thus, noninvasive cost-effective tests through which high-risk EV children can be...
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Impact of respiratory motion on liver stiffness measurements according to different shear wave elastography techniques and region of interest methods: a phantom study

Lee JH, Lee SM, Yoon JH, Kim MJ, Ha HI, Park SJ, Kim ES, Lee K, Lee JM

Purpose: This study quantified the impact of respiratory motion on liver stiffness measurements according to different shear wave elastography (SWE) techniques and region of interest (ROI) methods, using liver fibrosis...
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Diagnostic Performance of Serum Asialo α1 -Acid Glycoprotein Levels to Predict Liver Cirrhosis

Lim DH, Kim M, Jun DW, Kwak MJ, Yoon JH, Lee KN, Lee HL, Lee OY, Yoon BC, Choi HS, Kang BK

Background/Aims: To date, studies on various noninvasive techniques have been suggested to evaluate the degree of liver fibrosis. We aimed to investigate the diagnostic performance of se-rum asialo α1-acid glycoprotein...
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