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Correlation of HLA-Cw6 Positivity with Clinical Characteristics and Treatment Efficacy in Korean Patients with Psoriasis

Kim SM, Lee H, Lee ES

Background: Psoriasis is a multifactorial, chronic immunological disease, in which a specific allele HLA-Cw6 is associated with various clinical manifestations. However, information regarding this genetic factor in Korean patients with...
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Efficacy and Safety of Risankizumab for the Treatment of Moderate to Severe Psoriasis in Korea: A Real-Life Experience

Ko BC, Lee SM, Park HJ

  • KMID: 2531075
  • Korean J Dermatol.
  • 2022 Jun;60(5):307-315.
Background: Risankizumab is a humanized immunoglobulin G1 monoclonal antibody that selectively binds to the p19 subunit of interleukin-23. Risankizumab has demonstrated rapid and excellent therapeutic effects in several clinical trials....
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Comparison of Th1 and Th17 Inflammatory Cytokine Profiles Between Chronic Plaque and Acute Guttate Psoriasis

Ju HJ, Park HJ, Choi IH, Lee KH, Kwon MY, Park CJ

Background: The phenotypic heterogeneity of psoriasis is suspected to reflect differences in its pathogenesis, but not yet completely elucidated. Studies of the Th1 and Th17 cytokines associated with different phenotypes...
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Risk of Psoriasis in Postgastrectomy Gastric Cancer Survivors: A Nationwide Population-Based Cohort Study

Kim BR, Lee DH, Shim HI, Kim JW, Park S, Shin CM, Han K, Youn SW

Background: Although patients with psoriasis have an increased risk of cancers, little is known about the risk of psoriasis in cancer patients. Objective: We aimed to comparatively analyze the incidence and...
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Association Between Short-Term PASI90 Achievement and Drug Survival of Biologics in Patients with Psoriasis

Choi S, Oh S, Yoon HS

Background: With accumulating evidence that achieving a 90% improvement in the Psoriasis Area and Severity Index score (PASI90) has better correlation with improved healthrelated quality of life as compared to...
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Psoriatic Serum Induce an Abnormal Inflammatory Phenotype and a Decreased Immunosuppressive Function of Mesenchymal Stem Cells

Wang F, Hou R, Li J, Zhao X, Wang Q, Zhang K, Li X

Background and Objectives: Mesenchymal stem cells (MSCs) have immunomodulatory function and participate in the pathogenesis of many immunoregulation-related diseases, including psoriasis. Previously, we found that MSCs from psoriatic lesions overexpress...
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Effects of interleukin-17 inhibitors on hepatic fibrosis index in patients with psoriasis and metabolic dysfunction-associated fatty liver disease: Directed acyclic graphs

Takamura S, Teraki Y, Katayama E, Kawaguchi T, Kawaguchi M, Nakano D, Tsutsumi T, Nagoshi S, Nakama T, Torimura T

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Long-Term Analysis of Ustekinumab Therapy for Moderate-to-Severe Psoriasis in Korea

Kim Y, Bae KN, Son JH, Shin K, Kim H, Ko HC, Kim MB, Shin BS, Kim B

  • KMID: 2527677
  • Korean J Dermatol.
  • 2022 Mar;60(3):151-158.
Background: Ustekinumab is a humanized monoclonal antibody targeting interleukin (IL)-12 and IL-23. Although popular, data on its long-term efficacy and safety in Korean patients with psoriasis are limited. Objective: To evaluate...
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Successful Treatment of Recalcitrant Palmoplantar Pustulosis with Secukinumab: A Case Report

Min J, Her Y

  • KMID: 2526792
  • Korean J Dermatol.
  • 2022 Feb;60(2):140-142.
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A Case of Nummular Eczema-Like Eruption after Secukinumab Treatment

Eun DH, Kim D, Lee J, Yoon TY, Lee JY

  • KMID: 2526788
  • Korean J Dermatol.
  • 2022 Feb;60(2):135-138.
Secukinumab is an anti-interleukin 17A monoclonal antibody used for treating chronic plaque psoriasis. Eczematous eruption is a relatively unknown adverse effect of secukinumab. A 32-year-old man developed eczematous eruptions on...
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Efficacy and Safety of Oral Alitretinoin in Various Refractory Dermatologic Diseases: A Retrospective Study

Shon U, Choi MS, Park BC, Kim MH

  • KMID: 2526766
  • Korean J Dermatol.
  • 2022 Feb;60(2):91-98.
Background: Patients with dermatologic diseases refractory to conventional treatments including corticosteroids, immunosuppressants, and phototherapy require new treatment options. Limited studies have investigated the efficacy of alitretinoin for various diseases. Objective: This...
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Defining the Relationship between Daily Exposure to Particulate Matter and Hospital Visits by Psoriasis Patients

Lee EH, Ryu D, Hong NS, Kim JY, Park KD, Lee WJ, Lee SJ, Kim SH, Do Y, Jang YH

Background: Although particulate matter likely provokes inflammatory reactions in those with chronic skin disorders like atopic dermatitis, no study has examined the relationship between particulate matter and psoriasis exacerbation. Objective: This...
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Differences in Clinical Responses to Ustekinumab Treatment among Body Regions: Results from a Real-World Prospective, Observational, and Multi-Center Study in Korea

Son SW, Yu DY, Kim Y, Ahn HH, Jang YH, Roh JY, Lee YB, Lee JY, Kim MH, Lee Y, Park GH, Yoon HS, Youn SW, on behalf of the Stelara PMS investigators

Background: In psoriasis treatment, not all body regions improve simultaneously after clinical interventions. Objective: This study was aimed at evaluating clinical responses across body regions, which may differentially influence patient treatment...
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Principal Component Analysis to Differentiate Patients with Palmoplantar Pustulosis from Those with Palmoplantar Pustular Psoriasis

Kim TH, Kim JS, Kwon JE, Park B, Lee ES

Background: Palmoplantar pustulosis (PPP) is initiated from the acrosyringium. However, it is unclear whether PPP should be considered a distinct entity or should be classified into the spectrum of pustular...
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The Relationship between Systemic Anti-Psoriatic Treatment and Positive Interferon-Gamma Release Assay Rate in Moderate-Severe Korean Psoriasis Patients

Yang SY, Chun EJ, Kim JK, Kim SS, Kim CW

  • KMID: 2525566
  • Korean J Dermatol.
  • 2022 Jan;60(1):1-6.
Background: The relationship between latent tuberculosis and the use of certain biologics is well known, but the relationship between the test for latent tuberculosis results and psoriasis itself or systemic...
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Association of Psoriasis with Serum Vitamin D and Lipid Levels: A Clinical Review of Korean Patients in a Single Tertiary Referral Center

Park HJ, Lee HJ, Choi YJ, Kim WS, Lee GY

  • KMID: 2524130
  • Korean J Dermatol.
  • 2021 Dec;59(10):749-760.
Background: Psoriasis is a chronic inflammatory autoimmune disease. Some studies have demonstrated a relationship of psoriasis with vitamin D (Vit D) deficiency or serum lipid levels. Objective: We aimed to compare...
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Clinical Features and Treatment Considerations When Switching Biologics in Korean Patients with Severe Psoriasis: A Retrospective Single-Centered Study

Kim TH, Kim DC, Lee ES

  • KMID: 2522540
  • Korean J Dermatol.
  • 2021 Nov;59(9):707-712.
Background: Since the advent of biologics, they have been an efficient treatment for severe psoriasis vulgaris. Psoriasis that is refractory to biologics is associated with factors, such as old age,...
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In Vitro Models Mimicking Immune Response in the Skin

Moon S, Kim DH, Shin JU

The skin is the first line of defense of our body, and it is composed of the epidermis and dermis with diverse immune cells. Various in vitro models have been...
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A Case of Cutaneous Purpureocillium lilacinum Infection Looking like Psoriasis

Ha NG, Park KD, Bang YJ, Jun JB, Choi JS, Lee WJ

Purpureocillium lilacinum is a saprophytic fungus with a ubiquitous environmental distribution, and it can be detected in soil samples and decaying materials worldwide. It has been reported as an emerging...
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Histopathological and Immunohistochemical Differentiation between Psoriasis and Seborrheic Dermatitis of the Scalp: Based on Langerin and CD1a

Yoon JH, Park HR, Park EJ, Kim KJ, Kim KH

  • KMID: 2520802
  • Korean J Dermatol.
  • 2021 Sep;59(8):634-639.
Background: Psoriasis and seborrheic dermatitis are difficult to distinguish if the lesion is localized to the scalp. Objective: To validify the use of langerin and CD1a as markers of Langerhans cells...
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