Korean J Med.  1997 Mar;52(3):419-423.

A Case of Multifocal Cerebral Infarction Associated with Idiopathic Hypereosinophilic Syndrome

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea.

Abstract

The idiopathic hypereosinophilic syndrome represent a heterogenous group of disorders with common features of prolonged eosinophilia of an undetectable cause and organ system dysfunction. Recently, we experienced a case of idiopathic hypereosinophilic syndrome with multifocal cerebral infarction. The patient was 33-year-old male and visited our hospital with right upper extremity weakness and headache. The blood eosinophil counts were 8,316/mma and the marrow showed eosinophils were predominant and in mature forms The two-dimensional echocardiogram showed hyperechoic density at left ventricular apical wall without thrombus formation. Multifocal infarctions were seen at left cerebellar hemisphere, left thalamus, right frontal lobe and left periventricular white matter on brain MRI scan. No cause for hypereosinophilia was found. He was treated with prednisone and hydroxyurea.

Keyword

Hypereosinophilic syndrome; cerebral infarction

MeSH Terms

Adult
Bone Marrow
Brain
Cerebral Infarction*
Eosinophilia
Eosinophils
Frontal Lobe
Headache
Humans
Hydroxyurea
Hypereosinophilic Syndrome*
Infarction
Magnetic Resonance Imaging
Male
Prednisone
Thalamus
Thrombosis
Upper Extremity
Hydroxyurea
Prednisone
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